Wang, Chengcheng et al. published their research in Dyes and Pigments in 2022 | CAS: 1552-42-7

Crystal violet lactone (cas: 1552-42-7) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Quality Control of Crystal violet lactone

Preparation and property optimization of bistable electrochromic microcapsules was written by Wang, Chengcheng;Li, Jiashuang;Zhang, Liping;Fu, Shaohai. And the article was included in Dyes and Pigments in 2022.Quality Control of Crystal violet lactone This article mentions the following:

In the improvement of stability and lifetime of bistable electrochromic (EC) materials, the microcapsule technique was used to protect the EC materials in a polymer shell, which was named bistable EC microcapsules (BEC-Ms). However, the particle size and shell thickness of microcapsules will affect their properties, such as response time, coloration efficiency, and bistable property. In this study, BEC-Ms was prepared via solvent evaporation method filled with PMMA as the shell and the mixture of crystal violet lactone (CVL), tetrabutylammonium perchlorate (TBAP), and phase change material (PCM) as the core. The particle size and shell thickness of microcapsules were adjusted and systematically investigated by controlling the emulsification rate and mass ratio of polymer shell to core. The optimized BEC-Ms with 2 μm size and 22.94 nm thickness showed excellent performance including fast response time (about 1 s), far lower than the safety of human body drive voltage (2 V), coloration efficiency (932 cm2 C-1), and good bistability (216 h). This approach provides a viable and alternative to flexible energy-efficient wearable display-related devices and smart textiles. In the experiment, the researchers used many compounds, for example, Crystal violet lactone (cas: 1552-42-7Quality Control of Crystal violet lactone).

Crystal violet lactone (cas: 1552-42-7) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Quality Control of Crystal violet lactone

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Burlingame, Mark A. et al. published their research in ACS Combinatorial Science in 2011 | CAS: 4790-79-8

7-Methoxybenzofuran-2-carboxylic acid (cas: 4790-79-8) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.HPLC of Formula: 4790-79-8

Simple One-Pot Synthesis of Disulfide Fragments for Use in Disulfide-Exchange Screening was written by Burlingame, Mark A.;Tom, Christopher T. M. B.;Renslo, Adam R.. And the article was included in ACS Combinatorial Science in 2011.HPLC of Formula: 4790-79-8 This article mentions the following:

Disulfide exchange screening is a method for evaluating the binding of small mol. fragments to proteins that have at least one accessible cysteine. While operationally simple, it does require a large library of small fragment mols. bearing disulfide-containing side chains. These specialized fragments are not available com. and this has limited the adoption of the method. We report here a convenient one-pot procedure that enables facile preparation of disulfide screening fragments while also producing less of an environmental impact. The new synthetic method involves the initial formation of sym. disulfides, followed by a disulfide exchange reaction in which the sym. dimer is converted into the final screening fragment by introduction of a solubilizing “cap”. The method is amenable to parallel synthetic methods and can be carried out in air without the need for the specialized equipment typically required for performing organic synthesis. In the experiment, the researchers used many compounds, for example, 7-Methoxybenzofuran-2-carboxylic acid (cas: 4790-79-8HPLC of Formula: 4790-79-8).

7-Methoxybenzofuran-2-carboxylic acid (cas: 4790-79-8) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.HPLC of Formula: 4790-79-8

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Nagase, Kenichi et al. published their research in Scientific Reports in 2022 | CAS: 24280-93-1

(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid (cas: 24280-93-1) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.COA of Formula: C17H20O6

Chromatography columns packed with thermoresponsive-cationic-polymer-modified beads for therapeutic drug monitoring was written by Nagase, Kenichi;Takagi, Hikaru;Nakada, Hideo;Ishikawa, Haruki;Nagata, Yoshiko;Aomori, Tohru;Kanazawa, Hideko. And the article was included in Scientific Reports in 2022.COA of Formula: C17H20O6 This article mentions the following:

Therapeutic drug monitoring, which is used to determine appropriate drug doses, is critical in pharmacol. therapy. In this study, we developed thermoresponsive chromatog. columns with various cationic properties for effective therapeutic drug monitoring. Thermoresponsive cationic copolymer poly(N-isopropylacrylamide-co-Bu methacrylate-co-N,N-dimethylaminopropyl acrylamide) (P(NIPAAm-co-BMA-co-DMAPAAm))-modified silica beads, which were used as the chromatog. stationary phase, were prepared by modifying the radical initiator of the silica beads, followed by radical polymerization Characterization of the prepared silica beads demonstrated that thermoresponsive polymers with various cationic properties successfully modified the beads. The elution behavior of several steroids in the prepared bead-packed columns at various temperatures indicated that the optimal column operating temperature was 30 °C. Appropriate measurement conditions for 13 drugs were investigated by varying the cationic properties of the columns and the pH of the mobile phase. Drug concentrations in serum samples were determined using the developed columns and mobile phases with a suitable pH. Voriconazole concentrations in human serum samples were determined using the developed columns with all-aqueous mobile phases. We anticipate that the developed chromatog. columns can be used for therapeutic drug monitoring because drug concentrations can be measured using all-aqueous mobile phases that are suitable in clin. settings. In the experiment, the researchers used many compounds, for example, (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid (cas: 24280-93-1COA of Formula: C17H20O6).

(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid (cas: 24280-93-1) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.COA of Formula: C17H20O6

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Gless, Bengt H. et al. published their research in Journal of Organic Chemistry in 2018 | CAS: 3326-34-9

5-Amino-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 3326-34-9) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.COA of Formula: C20H13NO5

Direct peptide cyclization and one-pot modification using the MeDbz linker was written by Gless, Bengt H.;Olsen, Christian A.. And the article was included in Journal of Organic Chemistry in 2018.COA of Formula: C20H13NO5 This article mentions the following:

The one-pot synthesis and modification of cyclic peptides through a self-cleaving on-resin protocol is described. We apply Dawson’s MeDbz linker to achieve direct intramol. peptide cyclization by thioesterification followed by S → N acyl shift. This native chem. ligation approach requires no activating additive and allows direct modification of the crude cyclic peptides in one-pot. The strategy was applied to synthesize 5 cyclic peptide natural products of varying ring size. Finally, one-pot modifications include desulfurization, fluorophore conjugation, and intramol. disulfide formation. In the experiment, the researchers used many compounds, for example, 5-Amino-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 3326-34-9COA of Formula: C20H13NO5).

5-Amino-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 3326-34-9) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.COA of Formula: C20H13NO5

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Ohashi, Nami et al. published their research in Journal of Peptide Science in 2009 | CAS: 200115-86-2

H-Arg(Pbf)-OH (cas: 200115-86-2) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Computed Properties of C19H30N4O5S

Synthesis of protein kinase Cδ C1b domain by native chemical ligation methodology and characterization of its folding and ligand binding was written by Ohashi, Nami;Nomura, Wataru;Kato, Mai;Narumi, Tetsuo;Lewin, Nancy E.;Blumberg, Peter M.;Tamamura, Hirokazu. And the article was included in Journal of Peptide Science in 2009.Computed Properties of C19H30N4O5S This article mentions the following:

The C1b domain of protein kinase Cδ (PKCδ), a potent receptor for ligands such as diacylglycerol and phorbol esters, was synthesized by utilizing native chem. ligation. With this synthetic strategy, the domain was efficiently constructed and shown to have high affinity ligand binding and correct folding. The C1b domain has been utilized for the development of novel ligands for the control of phosphorylation by PKC family members. This strategy will pave the way for the efficient construction of C1b domains modified with fluorescent dyes, biotin, etc. In the experiment, the researchers used many compounds, for example, H-Arg(Pbf)-OH (cas: 200115-86-2Computed Properties of C19H30N4O5S).

H-Arg(Pbf)-OH (cas: 200115-86-2) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Computed Properties of C19H30N4O5S

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Aina, Valentina et al. published their research in Langmuir in 2014 | CAS: 3326-34-9

5-Amino-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 3326-34-9) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Formula: C20H13NO5

New Formulation of Functionalized Bioactive Glasses to Be Used as Carriers for the Development of pH-Stimuli Responsive Biomaterials for Bone Diseases was written by Aina, Valentina;Magistris, Claudio;Cerrato, Giuseppina;Martra, Gianmario;Viscardi, Guido;Lusvardi, Gigliola;Malavasi, Gianluca;Menabue, Ledi. And the article was included in Langmuir in 2014.Formula: C20H13NO5 This article mentions the following:

The aim of the present contribution is to prepare a functionalized bioactive glass potentially useful as prosthetic material, but also able to release organic mols. in response to a change of the pH environment. By this approach it is possible to develop devices which can be used for a triggered drug release in response to specific stimuli; this is an attractive research field, in order to avoid either systemic and/or local toxic effects of drugs. In particular, in the present paper we report data related to the development of a new formulation of bioactive glasses, their functionalization with organic mols. to obtain a pH-sensitive bond, their physicochem. characterization and in vitro bioactivity in simulated biol. fluids (SBF), and organic mol. delivery tests at different pH. The glass functionalization, by means of a covalent reaction, allows us to produce a model of pH-responsive bioactive biomaterial: when it is exposed to specific pH changes, it can favor the release of the organic mols. directly at the target site. Cysteamine and 5-aminofluorescein are used as model mols. to simulate a drug. The materials, before and after the different functionalization steps and in vitro release tests at different pH, have been characterized by means of different exptl. techniques such as X-ray powder diffraction (XRPD), Raman, FTIR and fluorescence spectroscopies, N2 adsorption, thermogravimetric (TGA) and elemental anal. In the experiment, the researchers used many compounds, for example, 5-Amino-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 3326-34-9Formula: C20H13NO5).

5-Amino-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 3326-34-9) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Formula: C20H13NO5

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Gupta, Juhi et al. published their research in Bioresource Technology in 2019 | CAS: 1563-38-8

2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Category: benzofurans

Production and characterization of extracellular polymeric substances (EPS) generated by a carbofuran degrading strain Cupriavidus sp. ISTL7 was written by Gupta, Juhi;Rathour, Rashmi;Singh, Rashmi;Thakur, Indu Shekhar. And the article was included in Bioresource Technology in 2019.Category: benzofurans This article mentions the following:

The present study demonstrates EPS production by Cupriavidus sp. ISTL7 along with its capability to remediate a toxic carbamate pesticide, carbofuran. The strain ISTL7 efficiently degraded approx. 98% of carbofuran (400 ppm) within 96 h. GC-MS anal. showed catabolic metabolites of degradation which included carbofuran-7-phenol, methylamine, 2-hydroxy-3-(3-methylpropan-2-ol)benzene-N-methyl-carbamate etc. EPS production from the mineral medium supplemented with carbofuran was observed to be 3.112 ± 0.3682 g L-1. FTIR confirmed its carbohydrate composition and the monomeric sugars: glucose, xylose, sorbitol and fructose were identified by GC-MS anal. The toxic potential of degradation experiment and the produced EPS was evaluated on HepG2 (mammalian liver cell line). The cytotoxicity of carbofuran was reduced upon bacterial degradation and the formed EPS was found to be non-toxic as inferred from percentage cell viability. The present research can possibly influence the development strategies of biol. remediation. In the experiment, the researchers used many compounds, for example, 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8Category: benzofurans).

2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Category: benzofurans

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Du, Guoxin et al. published their research in Medicinal Chemistry Research in 2022 | CAS: 128851-73-0

6-Bromobenzofuran (cas: 128851-73-0) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.Reference of 128851-73-0

Design, synthesis, and LFA-1/ICAM-1 antagonist activity evaluation of Lifitegrast analogues was written by Du, Guoxin;Du, Weiwei;An, Yuanlong;Wang, Minnan;Hao, Feifei;Tong, Xiaochu;Gong, Qi;He, Xiangdong;Jiang, Hualiang;He, Wei;Zheng, Mingyue;Zhang, Donglei. And the article was included in Medicinal Chemistry Research in 2022.Reference of 128851-73-0 This article mentions the following:

In this study, designed and synthesized some new structure compounds that were analogs to Lifitegrast, and their biol. activities were evaluated by in vitro cell-based assay and also by in vivo mouse dry eye model. The results demonstrated that one of these analogs of Lifitegrast (compound I = Ar1-X = (benzofuran-6-ylmethyl)carbamoyl, Ar2 = (methylsulfonyl)phenyl ) showed good LFA-1/ICAM-1 antagonist activity in in vitro assay; meanwhile, it also significantly reduced ocular surface epithelial cells damage, increased goblet cell d. in dry eye mouse and highly improved the symptoms of dry eye mouse. In the experiment, the researchers used many compounds, for example, 6-Bromobenzofuran (cas: 128851-73-0Reference of 128851-73-0).

6-Bromobenzofuran (cas: 128851-73-0) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.Reference of 128851-73-0

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Vene, Jean et al. published their research in Compt. rend. in 1952 | CAS: 4741-62-2

5-Methoxyisobenzofuran-1(3H)-one (cas: 4741-62-2) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Application In Synthesis of 5-Methoxyisobenzofuran-1(3H)-one

Activation energy and frequency factor in the alkaline hydrolysis of phthalides was written by Vene, Jean;Tirouflet, Jean;Carrie, Robert. And the article was included in Compt. rend. in 1952.Application In Synthesis of 5-Methoxyisobenzofuran-1(3H)-one This article mentions the following:

The alk. (0.002 M) hydrolysis is studied at 15°, 25°, 35°, and 45° in 20% EtOH (by weight) of phthalides (0.002 M) mono-substituted in the benzene nucleus in the 4, 5, 6, or 7 position by the groups: NH2, OCH3, Cl, and Br. For each of the derivatives in the 5, 6, and 7 positions and for the 4-methoxy-phthalide the factors PZ and E of the Arrhenius equation, k = PZ e-E/RT, remain constant within the limit of exptl. error. The ortho effect of substituents halogenated in the 7 position, responsible for the low value of the factor PZ in the case of o-halobenzoic esters, is considerably lessened for the phthalides. In the experiment, the researchers used many compounds, for example, 5-Methoxyisobenzofuran-1(3H)-one (cas: 4741-62-2Application In Synthesis of 5-Methoxyisobenzofuran-1(3H)-one).

5-Methoxyisobenzofuran-1(3H)-one (cas: 4741-62-2) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Application In Synthesis of 5-Methoxyisobenzofuran-1(3H)-one

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Clematis, Davide et al. published their research in Chemosphere in 2021 | CAS: 16423-68-0

Sodium 2′,4′,5′,7′-tetraiodo-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-bis(olate) (cas: 16423-68-0) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.Recommanded Product: 16423-68-0

Electro-Fenton, solar photoelectro-Fenton and UVA photoelectro-Fenton: Degradation of Erythrosine B dye solution was written by Clematis, Davide;Panizza, Marco. And the article was included in Chemosphere in 2021.Recommanded Product: 16423-68-0 This article mentions the following:

The treatment of Erythrosine B, selected as a model compound, has been comparatively studied by electrochem. advanced oxidation processes (EAOPs) such as electro-Fenton, UVA photoelectro-Fenton and solar photoelectro-Fenton at constant c.d. Experiments are performed in a one-compartment cell with a BDD anode, and a com. carbon felt cathode at pH = 3, treating a volume of 0.3 L in each test. The irradiation plays a crucial role in the increasing of hydroxyl radical production and in the recover of iron catalyst. A faster color and COD removal degradation are achieved under the light application. UVA photoelectro-Fenton and solar photoelectro-Fenton processes allow degrading COD entirely in 90 min, while a conventional electro-Fenton does not reach 90% COD removal after 2 h. Energy consumptions are a substantial factor in process selection. Photo electro-Fenton with a UVA-100 W lamp has one of the best removal performance, but it becomes not suitable for application due to high energy demand, up to 515.6 kWh m-3, and the UVA system requires the main fraction of this energy. Possible alternatives are proposed to contain costs: the first is the reduction of UVA lamp power to 25 W, maintaining a high-performance removal with an Ec decreasing to 187.9 kWh m-3. Nevertheless, the lowest and competitive energy demands is obtained working with a solar photoelectro-Fenton system, where energy consumption are only related to the electrochem. process (20.9 kWh m-3), and removal is complete. In the experiment, the researchers used many compounds, for example, Sodium 2′,4′,5′,7′-tetraiodo-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-bis(olate) (cas: 16423-68-0Recommanded Product: 16423-68-0).

Sodium 2′,4′,5′,7′-tetraiodo-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-bis(olate) (cas: 16423-68-0) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.Recommanded Product: 16423-68-0

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem