Ferro, Noel et al. published their research in Journal of Chemical Information and Modeling in 2006 | CAS: 62119-70-4

2-Benzofuranacetic acid (cas: 62119-70-4) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.COA of Formula: C10H8O3

Coulomb and Overlap Self-Similarities: A Comparative Selectivity Analysis of Structure-Function Relationships for Auxin-like Molecules was written by Ferro, Noel;Gallegos, Ana;Bultinck, Patrick;Jacobsen, Hans-Joerg;Carbo-Dorca, Ramon;Reinard, Thomas. And the article was included in Journal of Chemical Information and Modeling in 2006.COA of Formula: C10H8O3 This article mentions the following:

Auxins are defined mainly by a set of physiol. actions, but the structure-effect relationship still is based on chem. intuition. Currently a well-defined auxin mol. structure is not available. The existence of different auxin binding proteins and mechanisms of auxin action, the wide diversity of the auxin mols., and the pleiotropic effects of auxin imply a completely different mechanism as described for the animal hormone concept. Here, we present a computational approach dealing with semiempirical optimizations of the auxin mols. themselves, which represent a number of about 250 different chem. structures. Our approach uses mol. quantum similarity measures and addnl. quantum variables for the anal. of auxin-like mols. The finding of similarities in mols. by focusing basically on their electron structure results in new insights in the relationship of the different auxin groups. Addnl. statistical anal. allows the identification of relationships between similarity groups and their biol. activity, resp. It is postulated that the auxin-like mol. recognition depends more on specific mol. assembling states than on a specific ring system or side chain. In the experiment, the researchers used many compounds, for example, 2-Benzofuranacetic acid (cas: 62119-70-4COA of Formula: C10H8O3).

2-Benzofuranacetic acid (cas: 62119-70-4) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.COA of Formula: C10H8O3

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Ramella, Vincenzo et al. published their research in European Journal of Organic Chemistry in 2016 | CAS: 62119-70-4

2-Benzofuranacetic acid (cas: 62119-70-4) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Product Details of 62119-70-4

Palladium-Catalyzed Dearomatizing Difunctionalization of Indoles and Benzofurans was written by Ramella, Vincenzo;He, Zhiheng;Daniliuc, Constantin G.;Studer, Armido. And the article was included in European Journal of Organic Chemistry in 2016.Product Details of 62119-70-4 This article mentions the following:

A palladium-catalyzed dearomatizing difunctionalization of N-Boc-indoles and benzofurans to give tricyclic indolines and 2,3-dihydrobenzofurans with a fully substituted carbon center was described. Product formation occurred under mild conditions at room temperature with com. available aryl boronic acids and 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) as a mild oxidant in good yields. In the experiment, the researchers used many compounds, for example, 2-Benzofuranacetic acid (cas: 62119-70-4Product Details of 62119-70-4).

2-Benzofuranacetic acid (cas: 62119-70-4) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Product Details of 62119-70-4

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Li, Ya-Lan et al. published their research in Asian Journal of Organic Chemistry in 2021 | CAS: 62119-70-4

2-Benzofuranacetic acid (cas: 62119-70-4) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Application In Synthesis of 2-Benzofuranacetic acid

Chemo- and Site-Selective Fischer Esterification Catalyzed by B(C6F5)3 was written by Li, Ya-Lan;Pang, Jin-Yu;Lou, Ji-Cong;Sun, Wen-Wu;Liu, Ji-Kai;Wu, Bin. And the article was included in Asian Journal of Organic Chemistry in 2021.Application In Synthesis of 2-Benzofuranacetic acid This article mentions the following:

A direct and catalytic dehydrative esterification of carboxylic acids RC(O)OH [R = hept-1-yn-1-yl, 2-(naphthalen-2-yl)ethyl, (1-methyl-1H-indol-3-yl)methyl, 1-([(benzyloxy)carbonyl]amino)ethyl, etc.] with alcs. R1OH (R1 = Et, cyclohexyl, 2,3-dihydroxypropyl, etc.) is described. B(C6F5)3 is shown to be a highly effective catalyst for the Fischer esterification, providing esters RC(O)OR1 in high to excellent yields. This esterification shows excellent chemo- and site-selective monoesterification of various polyols R1OH without any protection step, including bio-derived mol. glycerol. In the experiment, the researchers used many compounds, for example, 2-Benzofuranacetic acid (cas: 62119-70-4Application In Synthesis of 2-Benzofuranacetic acid).

2-Benzofuranacetic acid (cas: 62119-70-4) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Application In Synthesis of 2-Benzofuranacetic acid

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Degenhardt, Charles R. et al. published their research in Synthetic Communications in 1982 | CAS: 62119-70-4

2-Benzofuranacetic acid (cas: 62119-70-4) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Computed Properties of C10H8O3

Use of tetraethyl dimethylaminomethylenediphosphonate in the synthesis of benzothiophene-2-acetic acid and other carboxylic acids was written by Degenhardt, Charles R.. And the article was included in Synthetic Communications in 1982.Computed Properties of C10H8O3 This article mentions the following:

Aldehydes I (R = H, Me) reacted with Me2NCH[P(O)(OEt)2]2 (II) to yield condensation products III, which were hydrolyzed to acids IV. I (R = H) was treated with II and NaH, and the III (R = H) obtained was heated with HCl to give IV (R = H). Similarly, 2-benzofuranacetic acid and Me(CH2)8CH2CHO were prepared from 2-benzofurancarboxaldehye and Me(CH2)8CHO. In the experiment, the researchers used many compounds, for example, 2-Benzofuranacetic acid (cas: 62119-70-4Computed Properties of C10H8O3).

2-Benzofuranacetic acid (cas: 62119-70-4) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Computed Properties of C10H8O3

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Ran, Chuan-Kun et al. published their research in ACS Catalysis in 2022 | CAS: 62119-70-4

2-Benzofuranacetic acid (cas: 62119-70-4) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Category: benzofurans

Visible-Light Photoredox-Catalyzed Carboxylation of Activated C(sp3)-O Bonds with CO2 was written by Ran, Chuan-Kun;Niu, Ya-Nan;Song, Lei;Wei, Ming-Kai;Cao, Yi-Fei;Luo, Shu-Ping;Yu, Yu-Ming;Liao, Li-Li;Yu, Da-Gang. And the article was included in ACS Catalysis in 2022.Category: benzofurans This article mentions the following:

A visible-light photoredox-catalyzed carboxylation of activated C(sp3)-O bonds with CO2 under mild and transition-metal-free conditions was reported. A variety of benzyl alcs. and derivatives, RCH(R1)OR2 (R = 4-phenylphenyl, 6-methoxynaphthalen-2-yl, 1-benzofuran-2-yl, etc.; R1 = H, Me, cyclohexyl, propan-2-yl, etc.; R2 = H, Piv, Ac) bearing primary, secondary, and more challenging tertiary C(sp3)-O bonds, undergo carboxylation with CO2, generating valuable aryl acetic acids RCH(R1)COOH, such as ibuprofen, naproxen, fenoprofen, and flurbiprofen, with broad substrate scope and good functional group tolerance. Moreover, this strategy is also applicable to other carboxylates of α-hydroxyl amides, esters, and nitriles, as well as allyl alcs., representing a practical method for aliphatic carboxylic acid synthesis. In the experiment, the researchers used many compounds, for example, 2-Benzofuranacetic acid (cas: 62119-70-4Category: benzofurans).

2-Benzofuranacetic acid (cas: 62119-70-4) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Category: benzofurans

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Ran, Chuan-Kun et al. published their research in ACS Catalysis in 2022 | CAS: 62119-70-4

2-Benzofuranacetic acid (cas: 62119-70-4) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Category: benzofurans

Visible-Light Photoredox-Catalyzed Carboxylation of Activated C(sp3)-O Bonds with CO2 was written by Ran, Chuan-Kun;Niu, Ya-Nan;Song, Lei;Wei, Ming-Kai;Cao, Yi-Fei;Luo, Shu-Ping;Yu, Yu-Ming;Liao, Li-Li;Yu, Da-Gang. And the article was included in ACS Catalysis in 2022.Category: benzofurans This article mentions the following:

A visible-light photoredox-catalyzed carboxylation of activated C(sp3)-O bonds with CO2 under mild and transition-metal-free conditions was reported. A variety of benzyl alcs. and derivatives, RCH(R1)OR2 (R = 4-phenylphenyl, 6-methoxynaphthalen-2-yl, 1-benzofuran-2-yl, etc.; R1 = H, Me, cyclohexyl, propan-2-yl, etc.; R2 = H, Piv, Ac) bearing primary, secondary, and more challenging tertiary C(sp3)-O bonds, undergo carboxylation with CO2, generating valuable aryl acetic acids RCH(R1)COOH, such as ibuprofen, naproxen, fenoprofen, and flurbiprofen, with broad substrate scope and good functional group tolerance. Moreover, this strategy is also applicable to other carboxylates of α-hydroxyl amides, esters, and nitriles, as well as allyl alcs., representing a practical method for aliphatic carboxylic acid synthesis. In the experiment, the researchers used many compounds, for example, 2-Benzofuranacetic acid (cas: 62119-70-4Category: benzofurans).

2-Benzofuranacetic acid (cas: 62119-70-4) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Category: benzofurans

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem