Use of tetraethyl dimethylaminomethylenediphosphonate in the synthesis of benzothiophene-2-acetic acid and other carboxylic acids was written by Degenhardt, Charles R.. And the article was included in Synthetic Communications in 1982.Computed Properties of C10H8O3 This article mentions the following:
Aldehydes I (R = H, Me) reacted with Me2NCH[P(O)(OEt)2]2 (II) to yield condensation products III, which were hydrolyzed to acids IV. I (R = H) was treated with II and NaH, and the III (R = H) obtained was heated with HCl to give IV (R = H). Similarly, 2-benzofuranacetic acid and Me(CH2)8CH2CHO were prepared from 2-benzofurancarboxaldehye and Me(CH2)8CHO. In the experiment, the researchers used many compounds, for example, 2-Benzofuranacetic acid (cas: 62119-70-4Computed Properties of C10H8O3).
2-Benzofuranacetic acid (cas: 62119-70-4) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Computed Properties of C10H8O3
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem