Electric Literature of 64175-51-5, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.64175-51-5, Name is 2-(Benzofuran-3-yl)acetic acid, molecular formula is C10H8O3. In a Article，once mentioned of 64175-51-5
The design and synthesis of a series of novel inhibitors of protein kinase C (PKC) is described.These 2,3-bisarylmaleimides were derived from the structural lead provided by the indolocarbazoles, staurosporine and K252a.Optimum activity required the imide NH, both carbonyl groups, and the olefinic bond of the maleimide ring. 2,3-Bisindolylmaleimides were the most active, and the potency of these was improved by a chloro substituent at the 5-position of one indole ring (compound 28, IC50 0.11 muM).In a series of (phenylindolyl)maleimides, nitro compound 74 was most active (IC50 0.67 muM).Naphthalene 19 and benzothiophene 21 showed greater than 100-fold selectivity for inhibition of PKC over the closely related cAMP-dependent protein kinase (PKA).
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 64175-51-5, and how the biochemistry of the body works.Electric Literature of 64175-51-5
Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H2661O – PubChem