Continuous-Flow Synthesis of Perfluoroalkyl Ketones via Perfluoroalkylation of Esters Using HFC-23 and HFC-125 under a KHMDS-Triglyme System was written by Fujihira, Yamato;Iwasaki, Hiroto;Sumii, Yuji;Adachi, Hiroaki;Kagawa, Takumi;Shibata, Norio. And the article was included in Bulletin of the Chemical Society of Japan in 2022.Recommanded Product: 1646-27-1 This article mentions the following:
Herein, a method for the chem. transformation of two HFCs, viz was described. HFC-23 and HFC-125, based on the continuous-flow perfluoroalkylation of esters to synthesize the pharmaceutically and agrochem. vital trifluoromethyl and pentafluoroethyl ketones. The combination of a potassium base and a glyme solvent system was found to be the most effective. The proposed method was attractive for industrial use because it allows the consumption of a large volume of HFCs, promotes the synthesis of high-value medicinal compounds, and serves as an ideal alternative to the current HFC decomposition processes like thermal plasma treatment. In the experiment, the researchers used many compounds, for example, Methyl benzofuran-2-carboxylate (cas: 1646-27-1Recommanded Product: 1646-27-1).
Methyl benzofuran-2-carboxylate (cas: 1646-27-1) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Recommanded Product: 1646-27-1
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem