Tag: 200-300

Gram scale synthesis of Fe/Fe_xO_y core-shell nanoparticles and their incorporation into matrix-free superparamagnetic nanocomposites was written by Watt, John;Bleier, Grant C.;Romero, Zachary W.;Hance, Bradley G.;Bierner, Jessica A.;Monson, Todd C.;Huber, Dale L.. And the article was included in Journal of Materials Research in 2018.Name: 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione This article mentions the following:

Significant reductions recently seen in the size of wide-bandgap power electronics have not been accompanied by a relative decrease in the size of the corresponding magnetic components. To achieve this, a new generation of materials with high magnetic saturation and permeability are needed. Here, we develop gram-scale syntheses of superparamagnetic Fe/Fe_xO_y core-shell nanoparticles and incorporate them as the magnetic component in a strongly magnetic nanocomposite. Nanocomposites are typically formed by the organization of nanoparticles within a polymeric matrix. However, this approach can lead to high organic fractions and phase separation; reducing the performance of the resulting material. Here, we form aminated nanoparticles that are then cross-linked using epoxy chem. The result is a magnetic nanoparticle component that is covalently linked and well separated By using this ‘matrix-free’ approach, we can substantially increase the magnetic nanoparticle fraction, while still maintaining good separation, leading to a superparamagnetic nanocomposite with strong magnetic properties. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Name: 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.Name: 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

An examination of analysis of histamine in food for health risk management was written by Hanaishi, Ryuji;Yamamoto, Akemi. And the article was included in Aomori-ken Kankyo Hoken Senta Kenkyu Hokoku in 2019.Formula: C17H10O4 This article mentions the following:

A rapid anal. method of histamine in food for health risk management cases was explored. As a basic technique, the present authors adopted a method already reported by Kikuchi et al. (Hiroyuki Kikuchi et al., 2012), in which the eluted solution purified by solid-phase extraction using a C18 cartridge and a strongly acidic cation exchange resin cartridge was derivatized with fluorescamine. The method was modified using tetrabutylammonium hydroxide (TBAH) as a base in the eluted solution in the purification step to shorten the time required for anal. At the time of drawing a calibration line based on the results of standard solution measurement, percent differences were calculated and the ranges of the calibration line were determined, and spike recovery rates were calculated using sardine dried whole. Using the TBAH method, sufficient recovery rates were obtained, suggesting that the TBAH method was useful as an anal. method in health risk management. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Formula: C17H10O4).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.Formula: C17H10O4

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

“One-Pot” Synthesis of γ-Pyrones from Aromatic Ketones/Heteroarenes and Carboxylic Acids was written by Sun, Xiangyu;Gong, Ming;Huang, Mengmeng;Li, Yabo;Kim, Jung Keun;Kovalev, Vladimir;Shokova, Elvira;Wu, Yangjie. And the article was included in Journal of Organic Chemistry in 2020.Related Products of 38220-75-6 This article mentions the following:

Despite the various attractive properties of γ-pyrones, there are still some deficiencies in their synthetic approaches such as lower atom economy, multistep processes, and prefunctionalization of the reagents. In this work, an efficient and simple (CF₃CO)₂O/CF₃SO₃H-mediated “one-pot” approach was realized to produce γ-pyrones by applying aromatic ketones/heteroarenes and carboxylic acids as the starting materials. The target products were isolated in moderate to excellent yields. The reaction mechanism was studied by d. functional theory calculational methods. The results of exptl. and theor. investigations not only helped us explain the reason of high selectivity formation of β-diketones but also proved that 1,3,5-ketones might be important intermediates for the cyclization to afford γ-pyrones. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Related Products of 38220-75-6).

1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Related Products of 38220-75-6

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Synthesis and biological activities of some new substituted benzofuranopyridines was written by Tirlapur, Vijay Kumar;Basawaraj, Raga;Prasad, Y. Rajendra. And the article was included in Indian Journal of Heterocyclic Chemistry in 2010.Safety of 1-(5-Bromobenzofuran-2-yl)ethanone This article mentions the following:

The condensation of 2-acetyl-5-bromobenzofuran, aldehydes, and Et cyanoacetate or malononitrile in EtOH in the presence of NH₄OAc gave 2-oxo-1,2-dihydro- and 2-amino-4-aryl-6-(5-bromobenzofur-2-yl)nicotinonitriles, resp. All the newly synthesized compounds were characterized by IR, ¹H NMR and mass spectra and were evaluated for their antitubercular, antibacterial, and antifungal activity. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Safety of 1-(5-Bromobenzofuran-2-yl)ethanone).

1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Safety of 1-(5-Bromobenzofuran-2-yl)ethanone

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Direct Production of Microstructured Surfaces for Planar Chromatography Using 3D Printing was written by Macdonald, Niall P.;Currivan, Sinead A.;Tedone, Laura;Paull, Brett. And the article was included in Analytical Chemistry (Washington, DC, United States) in 2017.Reference of 38183-12-9 This article mentions the following:

Through optimization of the printing process and orientation, a suitably developed surface area was realized upon a 3-dimensional printed polymer substrate to facilitate chromatog. separations in a planar configuration. Using an Objet Eden 260VS 3-dimensional printer, polymer thin layer chromatog. platforms were directly fabricated without any addnl. surface functionalization and successfully applied to the separation of various dye and protein mixtures The print material was characterized using gas chromatog. coupled to mass spectrometry and spectroscopic techniques such as IR and Raman. Preliminary studies included the separation of colored dyes, whereby the separation performance could be visualized optically. Subsequent separations were achieved using fluorescent dyes and fluorescently tagged proteins. The separation of proteins was affected by differences in the isoelec. point (pI) and the ion exchange properties of the printed substrate. The simple chromatog. separations are the 1st achieved using an unmodified 3-dimensional printed stationary phase. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Reference of 38183-12-9).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Reference of 38183-12-9

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Distinct Morphological Transitions of Photoreactive and Thermoresponsive Vesicles for Controlled Release and Nanoreactors was written by Yao, Chenzhi;Wang, Xiaorui;Liu, Guhuan;Hu, Jinming;Liu, Shiyong. And the article was included in Macromolecules (Washington, DC, United States) in 2016.Electric Literature of C17H10O4 This article mentions the following:

The construction of intelligent vesicular nanocarriers and nanoreactors has received increasing interests due to their potential in mimicking natural counterparts such as cells and organelles. Herein, we report thermoresponsive and photoreactive vesicles could be fabricated from amphiphilic block copolymers (BCPs), poly(N-isopropylacrylamide)-b-poly(2-((((2-nitrobenzyl)oxy)carbonyl)amino)ethyl acrylate) (PNIPAM-b-PNBOCA), which were synthesized via consecutive reversible addition-fragmentation chain transfer (RAFT) polymerizations The resulting BCPs self-assembled into vesicles when temperatures were lower than the lower critical solution temperature (LCST) of PNIPAM blocks (defined as LCST₀). However, the resulting vesicles irreversibly formed collapsed vesicles upon temperature rise (T > LCST₀), and a further temperature increase (T > T_agg,0) led to the formation of irregular aggregates of collapsed vesicles. On the other hand, upon UV irradiation, the initially hydrophobic PNBOCA bilayers underwent aminolysis-induced crosslinking and hydrophobic-to-hydrophilic transition, resulting in elevated LCST (defined as LCST_uv). Although the thermo-induced collapse of PNIPAM coronas (T > LCST_uv) and the formation of aggregates of cross-linked vesicles (T > T_agg,uv) were observed, the initially vesicular morphol. could be restored when cooling to lower than LCST_uv, as opposed to irreversible morphol. transition without UV irradiation The vesicular assemblies were engineered as nanocarriers for both hydrophilic (doxorubicin hydrochloride, DOX) and hydrophobic (Nile red, NR) payloads. The corelease profiles could be delicately regulated by both temperature variations and UV irradiation Interestingly, DOX release could be also regulated by thermo-induced vesicle collapse without recourse to UV irradiation or by near-IR (NIR) irradiation-induced vesicle collapse in the presence of photothermal agents coloaded within vesicular interiors as a result of the relatively low glass transition temperature of PNBOCA blocks. Moreover, nanoreactors were constructed by loading glucose oxidase (GO_x) into the aqueous interiors of the vesicles, allowing for activating fluorogenic reactions by UV irradiation and temperature change. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Electric Literature of C17H10O4).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Electric Literature of C17H10O4

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

A convenient, bio-inspired approach to the synthesis of multi-functional, stable fluorescent silica nanoparticles using poly(ethylene-imine) was written by Bauer, Christina A.;Chi, Gregory;Likens, Olivia Q.;Brown, Sandra M.. And the article was included in Nanoscale in 2017.Synthetic Route of C17H10O4 This article mentions the following:

Branched poly(ethylene-imine) can be tagged with luminescent dyes (e.g., fluorescein isothiocyanate and tetramethylrhodamine isothiocyanate) and used to precipitate spherical silica particles from 10s-to-100s of nm diameter size under mild conditions. These dye-PEI/SiO₂ nanoparticles are highly compatible with polar solvents to give bright fluorescent suspensions, and detailed photophys. characterization reveals well-separated dye moieties with an approx. homogeneous dispersion of dye-PEI conjugate throughout the SiO₂ matrix. Reaction of PEI amine groups incorporated at the particle surface affords a simple method for post-synthesis functionalization of these materials, and the formation of FITC/Eosin-Y fluorescence resonance energy transfer pair-tagged particles and SiO₂@Au core-shell nanocomposites using this strategy is demonstrated. This bio-inspired approach to multi-functional SiO₂ nanoparticles provides a range of potential advantages over traditional “inorganic” syntheses of similar materials, as it proceeds through a scalable, single-step reaction using inexpensive reagents, enables efficient incorporation of luminescent species into the resulting particles with very limited dye aggregation, and provides nanoparticles that do not require post-synthesis modification for further conjugation with species of interest. The method offers a simple means to generate complex nanocomposites, whereby a host of desired species can be incorporated both inside and on the surface of biocompatible SiO₂ nanoparticles. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Synthetic Route of C17H10O4).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.Synthetic Route of C17H10O4

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Synthesis and antimicrobial activity of fused isatin and diazepine derivatives derived from 2-acetyl benzofuran was written by Kenchappa, R.;Bodke, Y. D.;Telkar, S.;Nagaraja, O.. And the article was included in Russian Journal of General Chemistry in 2017.Formula: C10H7BrO2 This article mentions the following:

Acetyl benzofurans reacted with isatins in the presence of pyridine to give corresponding 3-[2-(1-benzofuran-2-yl)-2-oxoethyl]-3-hydroxy-1,3-dihydro-2H-indol-2-one derivatives I [R = H, Br; R¹ = H, Cl, MeO, etc.]. Dehydration of the latter in acidic media led to the corresponding α,β-unsaturated ketones II. The structures of newly synthesized compounds I and II were established on the basis of anal. and spectral data. The synthesized benzofuranyl(phenyl)dihydrospiro[1,4-diazepine]indolones III were screened for their antibacterial and antifungal activities. Compounds III [R = R¹ = Br; R = Br, R¹ = Cl; R = Br, R¹ = O₂N] displayed excellent antimicrobial activity. The synthesized compounds III were studied for docking on the enzyme glucosamine-6-phosphate synthase. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Formula: C10H7BrO2).

1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.Formula: C10H7BrO2

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Syntheses of biscationic, trypanocidal 1-benzofuran compounds was written by Dann, Otto;Char, Helmut;Griessmeier, Helmut. And the article was included in Liebigs Annalen der Chemie in 1982.Synthetic Route of C10H7BrO2 This article mentions the following:

Benzofurans I [R = CN, H₂N, C(:NH)NH₂ (Am), 2-imidazolidinyl, NHC(:NH)NH₂, NHCH:NMe₂, R¹ = NH₂, NHC(:NH)NH₂, NHCH:NMe₂, Br, CN, Am, 2-imidazolidinyl] were prepared by substitution of 2,5-(OH)RC₆H₃CHO with 4-R¹C₆H₄CH₂X (X = Cl, Br) followed by intramol. cyclocondensation. Addnl. obtained were II (R² = CO₂H, Ac, CO₂Et, CO₂Me, CHO, CH₂OH, CH₂Br, CH₂CN, CH₂CO₂H, R³ = Br, CN), II (R² = CONHC₆H₄R¹-4), and III [R = CN, Am, C(OEt):NH, X = NNHAm, NNHCSNH₂, NNHC₆H₄CN-4, NNHC₆H₄Am-4, O] and a number of alkenylene and alkylene bis(benzofurans). Arylated formamidine derivatives were prepared by reacting amine hydrochlorides with DMF in the presence of cyanamide. Selected derivatives had trypanosomicidal activity. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Synthetic Route of C10H7BrO2).

1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Synthetic Route of C10H7BrO2

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Simultaneous determination of 16 sulfonamide residues in beef by high performance liquid chromatography-fluorescence detection with online post-column derivatization was written by Xu, Xu;Xiao, Yuancan;Geng, Dandan;Pi, Li;Dong, Qi;Hu, Fengzu. And the article was included in Sepu in 2016.Category: benzofurans This article mentions the following:

In this study, we investigated the effects of the four kinds of derivatization reagents, including fluorescamine, o-phthaladehyde, fluorescein isothiocyanate isomer and 2,3-naphthalenedicarboxaldehyde. A high performance liquid chromatog. with fluorescence detection method for the rapid determination of 16 sulfonamide residues in beef was developed by using improved QuEChERS method for sample pretreatment and fluorescamine for online post-column derivatization. The beef samples were extracted with acetonitrile containing 1% (volume/volume) acetic acid, cleaned-up by QuEChERS method, injected for online post-column derivatization with fluorescamine, and then analyzed with fluorescence detection. Under the optimized conditions of QuEChERS and chromatog., the 16 sulfonamide residues showed good linearities in the range of 0.024-2.533 mg/L with the correlation coefficients (γ) higher than 0.992. The limits of detection of the method were 1.6 to 8.2 μg/kg. The average recoveries of the 16 sulfonamide residues were in the range of 66.6%-109.5% with the relative standard deviations from 0.9% to 9.9%. The method has the advantages of rapidity, simplicity, high sensitivity and better purification effect. It is suitable for the rapid determination of the sulfonamide residues in beef. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Category: benzofurans).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Category: benzofurans

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem