Dann, Otto et al. published their research in Liebigs Annalen der Chemie in 1982 | CAS: 38220-75-6

1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Synthetic Route of C10H7BrO2

Syntheses of biscationic, trypanocidal 1-benzofuran compounds was written by Dann, Otto;Char, Helmut;Griessmeier, Helmut. And the article was included in Liebigs Annalen der Chemie in 1982.Synthetic Route of C10H7BrO2 This article mentions the following:

Benzofurans I [R = CN, H2N, C(:NH)NH2 (Am), 2-imidazolidinyl, NHC(:NH)NH2, NHCH:NMe2, R1 = NH2, NHC(:NH)NH2, NHCH:NMe2, Br, CN, Am, 2-imidazolidinyl] were prepared by substitution of 2,5-(OH)RC6H3CHO with 4-R1C6H4CH2X (X = Cl, Br) followed by intramol. cyclocondensation. Addnl. obtained were II (R2 = CO2H, Ac, CO2Et, CO2Me, CHO, CH2OH, CH2Br, CH2CN, CH2CO2H, R3 = Br, CN), II (R2 = CONHC6H4R1-4), and III [R = CN, Am, C(OEt):NH, X = NNHAm, NNHCSNH2, NNHC6H4CN-4, NNHC6H4Am-4, O] and a number of alkenylene and alkylene bis(benzofurans). Arylated formamidine derivatives were prepared by reacting amine hydrochlorides with DMF in the presence of cyanamide. Selected derivatives had trypanosomicidal activity. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Synthetic Route of C10H7BrO2).

1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Synthetic Route of C10H7BrO2

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem