Direct Alkoxycarbonylation of Heteroarenes via Cu-Mediated Trichloromethylation and In Situ Alcoholysis was written by Luo, Wenkun;Jiang, Kai;Li, Yingwei;Jiang, Huanfeng;Yin, Biaolin. And the article was included in Organic Letters in 2020.SDS of cas: 1646-27-1 This article mentions the following:
An efficient approach for direct alkoxycarbonylation of furans I (R1 = iso-Pr, cyclopentyl, benzyl, etc.) as well as other heteroarenes, e.g., thiazole via a one-step copper-mediated reaction of three components (i.e., heteroarene, alc., and CHCl3) was reported. The copper additive was confirmed to simultaneously promote the reaction in three pathways: oxidant cracking, single electron transfer, and alcoholysis. By means of this protocol, various functionalized furancarboxylates II (R2 = Me, cyclopentyl, etc) and other heteroarenecarboxylates, e.g., Me benzo[d]thiazole-2-carboxylate were facilely obtained in moderate to good yields. In the experiment, the researchers used many compounds, for example, Methyl benzofuran-2-carboxylate (cas: 1646-27-1SDS of cas: 1646-27-1).
Methyl benzofuran-2-carboxylate (cas: 1646-27-1) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.SDS of cas: 1646-27-1
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem