Tag: M.W:200-300

127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, belongs to benzofurans compound, is a common compound. SDS of cas: 127264-14-6In an article, once mentioned the new application about 127264-14-6.

Compounds according to formula (I) are effective for the treatment of broncho-obstructive and inflammatory diseases.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3810O – PubChem

Application of 84102-69-2, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 84102-69-2, Ethyl (5-bromobenzofuran)-2-carboxylate, introducing its new discovery.

The present invention provides an antifungal agent that has superior antifungal action and is also superior in terms of physical properties, safety and metabolic stability. The present invention discloses a compound represented by the formula (I): (wherein X represents an oxygen atom, a sulfur atom or -NH-, R1 represents a hydrogen atom, a halogen atom, a cyano group, an amino group or a substituent, and R2 and R3 independently represent a hydrogen atom, a halogen atom, a hydroxyl group or a substituent, except for a case in which R2 and R3 are both hydrogen atoms), and an antifungal agent containing the above compound.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 84102-69-2. In my other articles, you can also check out more blogs about 84102-69-2

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H4031O – PubChem

Synthetic Route of 501892-90-6, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 501892-90-6, molcular formula is C10H7BrO3, introducing its new discovery.

Background: Two germ line Fc-gamma receptor (FCGR) polymorphisms, rs1801274 [FCGR2A; His(H)131Arg(R)] and rs396991 [FCGR3A; Phe(F)158Val(V)], produce altered proteins through amino acid substitutions. We previously reported that the FCGR2A H/H genotype was associated with longer overall survival (OS) in cetuximab-treated chemotherapy-refractory patients with metastatic colorectal cancer. Here, we aimed to replicate and extend this finding in the Canadian Clinical Trials Group CO.20 trial. Methods: After germ line DNA genotyping, polymorphic relationships with survival were assessed using log-rank tests and hazard ratios (HR) from Cox proportional hazard models, adjusting for known prognostic factors. The dominant genetic inheritance model was used for the main analysis. Results: Of 592 wild-type KRAS patients treated with cetuximab, those with the FCGR2A H/H genotype (n = 165, 28%) had improved OS (HR: 0.66, P < 0.001; median absolute benefit, 1.3 months) compared to those with R/- genotype (n = 427, 72%). Patients with H/R had intermediate results under a codominant genetic inheritance model (HR: 0.72, P = 0.003). No significant associations were found between FCGR3A genotype and OS. In an exploratory analysis, patients with the combination of FCGR2A H/H + FCGR3A F/F genotype had significantly better OS (HR: 0.33, P = 0.003; median absolute benefit, 12.5 months) than patients with the combination of double-variant R/R + V/V genotype. Progression-free survival results were similar to OS. Toxicity rates were not associated with either polymorphism. Conclusions: The FCGR2A genotype was associated with efficacy but not with toxicity in wild-type KRAS, cetuximab-treated colorectal cancer patients. FCGR3A genotype may modulate the relationship between FCGR2A polymorphism and outcome. FCGR2A is a promising biomarker for clinical management for these patients. The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 501892-90-6 is helpful to your research. Synthetic Route of 501892-90-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3980O – PubChem

Application of 286836-04-2, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 286836-04-2, Name is 5-Bromo-7-fluorobenzofuran, molecular formula is C8H4BrFO. In a Patent，once mentioned of 286836-04-2

The present invention provides serotonergic benzofurans of Formula (I) where A, R, R1, R2, R3, and R4 are as described in the specification.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 286836-04-2. In my other articles, you can also check out more blogs about 286836-04-2

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3634O – PubChem

Electric Literature of 253429-31-1, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.253429-31-1, Name is 7-Bromo-4-fluorobenzofuran, molecular formula is C8H4BrFO. In a article，once mentioned of 253429-31-1

The present invention provides the compounds of the following formula:Wherein the variables are as defined in the specification and a method for inhibiting the reuptake of seretonin, antagonizing the 5-HT 1A receptor and antagonizing the 5-HT 2A receptor which comprises administering to a subject in need of such treatment an effective amount of the compound of above formula.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 253429-31-1

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3644O – PubChem

652-12-0, Name is Tetrafluorophthalic anhydride, belongs to benzofurans compound, is a common compound. Computed Properties of C8F4O3In an article, once mentioned the new application about 652-12-0.

A series of zinc(II) porphyrinimide dyads (ZP-Im), in which an electron donating ZP moiety is directly connected to an electron accepting imide moiety in the meso position, have been prepared for the examination of energy gap dependence of intramolecular electron transfer reactions with large electronic coupling. The nearly perpendicular conformation of the imide moiety towards the porphyrin plane has been revealed by X-ray crystal structures. The energy gap for charge separation, 1Zp*-Im ? ZP+ – Im-, is varied by changing the electron accepting imide moiety to cover a range of about 0.8 eV in DMF. Definitive evidence for electron transfer has been obtained in three solvents (toluene, THF, and DMF) through picosecond-femtosecond transient absorption studies, which have allowed us to determine the rates of photoinduced charge separation, 1ZP*-Im?ZP+-Im-, and subsequent thermal charge recombination ZP+-Im-? ZP-Im. The free-energy gap dependence (energy gap law) has been probed from the normal to the nearly top region for the charge separation rate alone, and only the inverted region for the charge recombination rate. Although both of the energy gap dependencies can be approximately reproduced by means of the simplified semiclassical equation, when we take into consideration the effect of the high frequency vibrations replaced by one mode of averaged frequency, many features, including the effects of solvent polarity and the electron tunneling matrix element on the energy gap law, differ considerably from those of the previously studied porphyrin – quinone systems, which have weaker interchromophore electronic interactions.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3780O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Product Details of 805250-17-3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 805250-17-3, Name is Methyl 2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate, molecular formula is C11H12O4

The invention relates to a kind of formula (I) a novel nitrogen-containing heterocyclic derivatives, its preparation method and a pharmaceutical composition containing the derivative as a preparation for the treatment of diabetes, metabolic syndrome pharmaceutical use. The nitrogen-containing heterocyclic derivatives have an excellent hypoglycemic activity in vivo, it can be used for the prevention or treatment of diabetes. (by machine translation)

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Product Details of 805250-17-3, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 805250-17-3, in my other articles.

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3541O – PubChem

Reference of 10242-11-2, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 10242-11-2, molcular formula is C9H5BrO3, introducing its new discovery.

Compounds of formula (I) wherein X is a fluorine or a chlorine atom; the methyl groups located at the 2- and 5-position of the piperazine ring are in trans-configuration to each other; Y is NH or O; R1 is selected front hydrogen, chloro, bromo, nitro, methyl or trifluoromethyl; R2 is selected from hydrogen, halo, methyl, trifluoromethyl, methoxy or trifluoromethoxy; or a pharmaceutically acceptable salt or solvate thereof, The invention also relates to pharmaceutical compositions containing a compound of formula (I) together with a pharmaceutically acceptable carrier. Included are also processes for the preparation of compounds of formula (I), as well as methods for treating mammals suffering from inflammatory, autoimmune, proliferative or hyperproliferative diseases by administering a compound having the formula (I) to said mammal.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 10242-11-2 is helpful to your research. Reference of 10242-11-2

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3904O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Quality Control of 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, molecular formula is C10H11BrO

A process for preparing substituted pyrrolidine compounds, including (5)-2-{l-[2- (2,3-dihydrobenzofuran-5-yl)ethyl]-3-pyrrolidinyl}-2,2-diphenylacetamide hydrobromide, commonly known in the art as darifenacin, comprising reacting a pyrrolidine compound with a benzofuran derivative in the presence of a phase-transfer catalyst.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Quality Control of 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 127264-14-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3833O – PubChem

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Product Details of 10242-11-2, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 10242-11-2, name is 5-Bromobenzofuran-2-carboxylic acid. In an article，Which mentioned a new discovery about 10242-11-2

Mono-acylated o-phenylendiamines derivatives of formula I wherein X and R are as described herein, have been found useful for the treatment of diseases mediated by the inhibition of histone deacetylase, such as cancer.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 10242-11-2, help many people in the next few years.Product Details of 10242-11-2

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3905O – PubChem