Category: 127264-14-6

Synthetic Route of 127264-14-6, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran,introducing its new discovery.

The invention relates to a darifenacin intermediate – 2, 3 – dihydro – 5 – benzofuran acetic acid. By the P-hydroxy-acetic acid and bromo acetaldehyde acetal as the starting material, the presence of O – alkylation reaction under a condition of the corresponding ether compound; then by esterification reaction to obtain the corresponding ester; in PPA (poly phosphoric acid) under the action of the, cyclization to obtain 2, 3 – benzofuran – 5 – acetate; 2, 3 – benzofuran – 5 – acetic acid layer which hydrolysis, to acidify the corresponding carboxylic acid; obtained by catalytic hydrogenation of 2, 3 – dihydro – 5 – benzofuran acetic acid; or the first 2, 3 – benzofuran – 5 – acetate obtained by catalytic hydrogenation of 2, 3 – dihydro – 5 – benzofuran acetic acid esters; and hydrolyzed, acidified to obtain 2, 3 – dihydro – 5 – benzofuran acetic acid. The method of the invention by simple and safe, each reaction raw materials are cheap and easy to obtain, the reaction yield is high, and is particularly suitable for industrial production of 2, 3 – dihydro – 5 – benzofuran acetic acid. (by machine translation)

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 127264-14-6, and how the biochemistry of the body works.Synthetic Route of 127264-14-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3825O – PubChem

Application of 127264-14-6, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, molecular formula is C10H11BrO. In a Patent，once mentioned of 127264-14-6

Amines of the following formula: STR1 where the variables are defined in the specification are useful in the treatment of diseases associated with altered motility and/or tone of smooth muscle.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 127264-14-6. In my other articles, you can also check out more blogs about 127264-14-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3805O – PubChem

Electric Literature of 127264-14-6, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, molecular formula is C10H11BrO. In a Article，once mentioned of 127264-14-6

1,1-Diarylalkanes are important structural frameworks which are widespread in biologically active molecules. Herein, we report a reductive relay cross-coupling of alkyl bromides with aryl bromides by nickel catalysis with a simple nitrogen-containing ligand. This method selectively affords 1,1-diarylalkane derivatives with good to excellent yields and regioselectivity.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 127264-14-6. In my other articles, you can also check out more blogs about 127264-14-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3838O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Product Details of 127264-14-6, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, molecular formula is C10H11BrO

The present invention discloses an improved process for producing darifenacin, the process comprising decarboxylating (2S,4R)-4-hydroxy-2-pyrrolidine carboxylic acid followed by in situ tosylation to give l-tosyl-3-(R)-(-)-hydroxypyrrolidine, tosylating the l-tosyl-3-(R)-(-)-hydroxypyrrolidine with methyl-p-toluenesuolphonate to give l-tosyl-3- (S)-(-)-tosyloxy pyrrolidine, reacting l-tosyl-3-(S)-(-)-tosyloxy pyrrolidine with diphenyl acetonitrile in presence of a base to give 3-(S)-(+)-(l-cyano-l,l-diphenylmethyl)-l- tosylpyrrolidine, de-protecting 3-(S)-(+)-(l-cyano-l,l-diphenylmethyl)-l- tosylpyrrolidine in the presence of phenol in acidic medium to give 3-(S)-(+)-(l-cyano- 1,1-diphenylmethyl) pyrrolidine, hydrolyzing 3-(S)-(+)-(l-cyano-l,l-diphenylmethyl) pyrrolidine followed by salt formation to obtain 3-(S)-(+)-(l-carbamoyl-l,l- diphenylmethyl)pyrrolidine.L-(+)-tartrate, condensing 3-(S)-(+)-( 1 -carbamoyl- 1,1- diphenylmethyl)pyrrolidine-L(+)-tartrate with 5-(2-bromoethyl)-2,3-dihydrobenzofuran employing a base in a solvent to give darifenacin.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Product Details of 127264-14-6, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 127264-14-6, in my other articles.

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3835O – PubChem

Application of 127264-14-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, molecular formula is C10H11BrO. In a Patent，once mentioned of 127264-14-6

The invetion is a method of treating irritable bowel syndrome with a compound selected from the formula STR1 wherein R, R 1, m, n p are as defined in the specification, or a pharmaceutically acceptable salt thereof.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 127264-14-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3808O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, SDS of cas: 127264-14-6, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, molecular formula is C10H11BrO

Disclosed herein are substituted pyrrolidine-based muscarinic receptor modulators of Formula I, process of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, SDS of cas: 127264-14-6, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 127264-14-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3834O – PubChem

Synthetic Route of 127264-14-6, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 127264-14-6, 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, introducing its new discovery.

Compounds of the formula STR1 and the pharmaceutically acceptable salts thereof, wherein: Y is a direct link, –CH 2 –, –(CH 2) 2 –, –CH 2 O– or –CH 2 S–; R is –CN or –CONH 2 ; and R 1 is STR2 where X and X 1 are each independently O or CH 2 ; and m is 1, 2 or 3, are muscarinic receptor antagonists useful in the treatment of diseases and conditions associated with the altered motility and/or tone of smooth muscle, such as irritable bowel syndrome.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 127264-14-6. In my other articles, you can also check out more blogs about 127264-14-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3819O – PubChem

Application of 127264-14-6, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, molecular formula is C10H11BrO. In a Patent，once mentioned of 127264-14-6

The present invention relates to compounds acting as muscarinic receptor antagonists, to methods of preparing such derivatives, to compositions comprising them and therapeutic use thereof.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 127264-14-6. In my other articles, you can also check out more blogs about 127264-14-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3811O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, name: 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, molecular formula is C10H11BrO

A highly regioselective Ni-catalyzed electrochemical reductive relay cross-coupling between an aryl halide and an alkyl halide has been developed in an undivided cell. Various functional groups are tolerated under these mild reaction conditions, which provides an alternative approach for the synthesis of 1,1-diarylalkanes.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, name: 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 127264-14-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3836O – PubChem

Electric Literature of 127264-14-6, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, molecular formula is C10H11BrO. In a article，once mentioned of 127264-14-6

A new copper-catalyzed trifluoromethylarylation reaction of alkynes has been developed. The transformation represents the first example of endo-type carbotrifluoromethylation of unsaturated carbon-carbon bonds and provides efficient access to a variety of CF3-substituted dihydronaphthalenes and chromenes.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 127264-14-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3842O – PubChem