Category: 127264-14-6

Chemistry is traditionally divided into organic and inorganic chemistry. Application In Synthesis of 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 127264-14-6

The present invention relates to novel and improved processes for the preparation of intermediates of darifenacin, darifenacin and its pharmaceutically acceptable salts. Darifenacin is chemically known as 3 -(S)-(-)-(l -carbamoyl- 1,1 -diphenylmethyl)-l- [2- (2,3-dihydro benzofuran-5-yl)ethyl]pyrrolidine and represented by formula-2. The invention also relates to the novel polymorphs of the pharmaceutically acceptable salts of darifenacin and the methods for their re aration.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3832O – PubChem

Synthetic Route of 127264-14-6, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, molecular formula is C10H11BrO. In a Patent，once mentioned of 127264-14-6

A compound of the formula (IA) or (IB), useful in treating diseases associated with the altered motility and/or tone of smooth muscle, such as irritable bowel syndrome, of the formula:- and their pharmaceutically-acceptable salts, where Y is-CH?CH?-,-CH=CH-,-CH?-S-,-CH?-O-,-O-or-S-; and X is a group of the formula:- wherein m is 1 or 2; R1 and R2 are each independently H or C?-C? alkyl or together represent-(CH?)n-where n is an integer of from 2 to 5; R3 is H or C?-C? alkyl; Z is a direct link,-CH?-,-(CH? )?-,-CH?O-or-CH?S-; and R? is pyridyl, pyrazinyl, thienyl or a group of the formula:- where either R? and R? are each independently selected from H, C?-C? alkyl, C?-C? alkoxy, halo,-CF?,-CN,-(CH?) pNR? R?,-OCO(C?-C? alkyl),-CO(C?-C? alkyl),-CH(OH)(C?-C? alkyl),-C(OH) (C?-C? alkyl)?,-SO?NH?,-NHSO?(C?-C? alkyl),-(CH?)pOH,-(CH?)p COO(C?-C? alkyl),-(CH?)pCONR? R?, or R? and R? together represent-(CH?)q-,-O(CH?) rO-or-O(CH? )t-where in the latter the oxygen atom is attached to the 3-or 4-position of the benzene ring; R? and R? are each independently H or C?-C? alkyl; p is 0, 1 or 2; q is 3, 4 or 5; r is 1, 2 or 3; and t is 2, 3 or 4.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 127264-14-6. In my other articles, you can also check out more blogs about 127264-14-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3821O – PubChem

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. HPLC of Formula: C10H11BrO, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 127264-14-6, name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran. In an article，Which mentioned a new discovery about 127264-14-6

The invention relates to a darifenacin intermediate – 2, 3 – dihydro – 5 – benzofuran acetic acid for the preparation of the new method. Under the action of the Lewis acid, by 2, 3 – dihydrobenzofuran as the starting material, and oxalyl chloride single ethyl ester via Friedel – Crafts acylation reaction to obtain the corresponding acyl compound; obtained after the hydrolysis of alpha – keto acid sodium salt; reuse Wolff – Kishner – Huang min reaction, the carbonyl reduction into methylene, acidified by 2, 3 – dihydro – 5 – benzofuran acetic acid. The method of the invention by simple and safe, each reaction raw materials are cheap and easy to obtain, the reaction yield is high, in particular suitable for industrialized production 2, 3 – dihydro – 5 – benzofuran acetic acid. (by machine translation)

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3824O – PubChem

Electric Literature of 127264-14-6, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran,introducing its new discovery.

Compounds of the formula I STR1 wherein X, Y and v are as defined below, novel intermediates used in their synthesis, and the pharmaceutically acceptable salts of such compounds and intermediates. The compounds of formula I and the novel intermediates used in their synthesis are muscarinic receptor antagonists that are selected for smooth muscle muscarinic sites and are useful in the prevention and treatment of diseases associated with altered motility or tone of smooth muscle, such as irritable bowel syndrome, diverticular disease, urinary incontinence, aesophageal achalasia, and chronic obstructive airways disease.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3818O – PubChem

Synthetic Route of 127264-14-6, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 127264-14-6, molcular formula is C10H11BrO, introducing its new discovery.

Selective muscarinic receptor antagonists of formula (I): STR1 wherein R 1 and R 2 are both optionally substituted phenyl, the broken line is an optional bond, X is > COH–, > SiOH–or CH–when the double bond is absent or is > C= when the double bond is present, X being attached to a carbon atom of A, A is selected from certain piperidine and pyrrolidine groups, n is 1 to 3 and R 3 is optionally substituted phenyl or thienyl, pyridyl or pyrazinyl.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 127264-14-6 is helpful to your research. Synthetic Route of 127264-14-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3806O – PubChem

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 127264-14-6, name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, introducing its new discovery. Formula: C10H11BrO

MUSCARINIC RECEPTOR ANTAGONISTS OF THE FOLLOWING FORMULAE: STR1 Muscarinic receptor antagonists, useful especially in the treatment of irritable bowel syndrome, of formula (IA) or (IB) or a pharmaceutically acceptable salt thereof, where R 2 and R 3 are each independently H, halo or C 1 -C 4 alkyl; m is 0, 1 or 2; n is 1, 2 or 3; Y is a direct link, O or S; with the proviso that when n is 1, Y is a direct link; Het is a group of formula (A) or (B), where p is 0, 1 or 2, q is 1, 2 or 3, and r is 0, 1, 2 or 3, with the proviso that the sum of p, q and r is at least 3, the N atom of “”Het”” being attached to the group (CH 2) n in formula (IA) and to the H atom in formula (IB); and R 1 is a group of formula (a), (b) or Het 1, where R 4 and R 5 are each independently H, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, –(CH 2) t OH, halo, trifluoromethyl, cyano, –(CH 2) t NR 6 R 7, –CO(C 1 -C 4 alkyl), –OCO(C 1 -C 4 alkyl), CH(OH)(C 1 -C 4 alkyl), –C(OH)(C 1 -C 4 alkyl) 2, –SO 2 NH 2, –(CH 2) t CONR 6 R 7 or –(CH 2) t COO(C 1 -C 4 alkyl); R 6 and R 7 are each independently H or C 1 -C 4 alkyl; t is 0, 1 or 2; X and X 1 are each independently O or CH 2 ; s is 1, 2 or 3; and Het 1 is pyridyl, pyrazinyl or thienyl.

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 127264-14-6, and how the biochemistry of the body works.Formula: C10H11BrO

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3807O – PubChem

127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, belongs to benzofurans compound, is a common compound. name: 5-(2-Bromoethyl)-2,3-dihydrobenzofuranIn an article, once mentioned the new application about 127264-14-6.

The invention provides named compounds of formula (I), wherein R4 is a N-substituted quinuclidine (I) pharmaceutical compositions containing them and a process for preparing the pharmaceutical compositions. Their use in therapy for? the treatment of conditions mediated by M3 muscarinic receptors, such as chronic obstructive pulmonary disease is also disclosed.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3815O – PubChem

Chemistry is traditionally divided into organic and inorganic chemistry. Product Details of 127264-14-6, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 127264-14-6

The present invention is directed to a novel, industrially viable and cost effective process for manufacturing (3 S)- 1 -[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-a,a-diphenyl-3-pyrrolidineacetamide hydrobromide also known as Darifenacin hydrobromide.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3830O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Formula: C10H11BrO, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 127264-14-6, Name is 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, molecular formula is C10H11BrO

The present invention provides compounds of Formula I, II, III or IV, or pharmaceutically acceptable salts and solvates thereof, which are useful as inhibitors of human immunodeficiency virus (HIV) and are also useful for the treatment of HIV infections in HIV- infected mammals, including humans. The present invention also provides pharmaceutical compositions comprising compounds of Formula I1 II, III or IV, and their pharmaceutically acceptable salts and solvates.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Formula: C10H11BrO, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 127264-14-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3814O – PubChem

Related Products of 127264-14-6, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 127264-14-6, molcular formula is C10H11BrO, introducing its new discovery.

The invention belongs to the technical field, of indomethacin synthesis, and discloses a synthesis method, of indomethacin and analogues thereof in :position introduction of an indole C2 position into an alkyl, aromatic ring or a heteroaromatic ring; to introduce the aroyl C3 at position of the indole; in the indole N1 position to solve the problem . of the existing indomethacin synthesis method in the later modification and structure-effect relation research of indomethacin molecules on the basis of the synthesis strategy. (by machine translation)

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 127264-14-6 is helpful to your research. Related Products of 127264-14-6

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3816O – PubChem