Category: benzofurans

Application of 652-12-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.652-12-0, Name is Tetrafluorophthalic anhydride, molecular formula is C8F4O3. In a Article，once mentioned of 652-12-0

In this paper we report the design, synthesis and pharmacological evaluation of a new series of phenyl sulfonamide derivatives 2a-h and 3-8 planned by structural modification on the anti-inflammatory prototype LASSBio-468 (1). Among the synthesized analogues, the tetrafluorophthalimide LASSBio-1439 (2e) stands out showing an in vitro anti-TNF-a effect similar to the standard thalidomide. The relevance of tetrafluorination of the phthalimide nucleus was also confirmed by the anti-inflammatory profile of 2e, through oral administration, in a murine model of pulmonary inflammation. The corresponding tetrafluorocarboxyamide metabolite LASSBio-1454 (15), generated from partial hydrolysis of the derivative 2e, presented a significant in vitro effect and a pronounced anti-inflammatory activity in vivo.

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Benzofuran – Wikipedia,
Benzofuran | C8H3717O – PubChem

Related Products of 66826-78-6, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 66826-78-6, Name is 5-Bromo-2,3-dihydrobenzofuran,introducing its new discovery.

The present invention relates to novel compounds of the formula I and the N-oxides, stereoisomers, tautomers and agriculturally or veterinarily acceptable salts thereof wherein C1 is C or CH; C2 is C or CH; A1 is N or C; A2 is N, C(R2), N(R3), O, S or C(R4,R5); and A3 is N, O, S, N(R6), C(R7) or C(R8,R9); where one or two non-adjacent bonds in the 5-membered ring formed by C1, C2, A1, A2 and A3 are double bonds, while the others are single bonds, provided that the bond between A1 and A2 or the bond between A1 and C1 or the bond between A2 and A3 or the bond between C1 and C2 or the bond between A3 and C2 is a double bond further provided that at least one of A1, A2 and A3 is N, N(R3) or N(R6), and where Ar, R1, R2, R3, R4,R5, R6, R7, R8, R9 and (R)k are as defined in the claims and in the description, which are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.

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Benzofuran – Wikipedia,
Benzofuran | C8H3347O – PubChem

Application of 166599-84-4, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 166599-84-4, Name is Benzofuran-4-carboxylic acid,introducing its new discovery.

Processes for preparing azacitidine. Further included are processes for the preparation of crystalline azacitidine crystalline Form (I) and mixtures of azacitidine crystalline Forms (I) and (II).

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Benzofuran – Wikipedia,
Benzofuran | C8H1613O – PubChem

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 125-20-2, name is Thymolphthalein, introducing its new discovery. Safety of Thymolphthalein

To optimize the anaerobic digestion of grape pomace under mesophilic conditions, continuous digesters were operated at different hydraulic retention times (HRT) (30, 20, 15 and 10 days) equivalent to organic loading rates (OLR) of 2.5, 3.7, 5.7 and 7.3 kg COD m?3 d?1, respectively. At HRTs of 30 and 20 days, steady state conditions were observed with methane yields of 0.984 ± 0.013 NL d?1 and 1.362 ± 0.018 NL d?1, respectively. The HRT of 15 days was found critical because of acids accumulation through the experiments. When the OLR of 5.7 kg COD m?3 d?1 was reached, methane production was found to be instable. Finally, at HRT of 10 days, a failure of the system was observed due to the washing of the methanogenic microorganisms. Regarding the degradability of the lignocellulosic fractions, the maximum reduction yields for hemicellulose and cellulose were noted for HRTs of 30 and 20 days, while lignin was not degraded throughout the different experiments. For an optimization of the process, HRT of 20 days can therefore be recommended for productive use in large-scale applications.

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Benzofuran – Wikipedia,
Benzofuran | C8H4293O – PubChem

Electric Literature of 54802-10-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.54802-10-7, Name is 3-Aminobenzofuran-2-carboxamide, molecular formula is C9H8N2O2. In a Article，once mentioned of 54802-10-7

The focus of this study was the development of a new synthetic method for quinazolinones based on the principles of Green Chemistry. Quinazolinones were synthesized from 2-aminobenzamide using methanol as both the C1 source and a green solvent in the presence of base Cs2CO3. Additionally, a commercially available, economical copper complex was used as a catalyst in the reaction. The desired products were achieved in moderate to high yield with up to 99 % isolated yield.

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Benzofuran – Wikipedia,
Benzofuran | C8H2818O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Recommanded Product: 54008-77-4, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 54008-77-4, Name is 2-Bromobenzofuran, molecular formula is C8H5BrO

A simple, efficient, regioselective, and scalable palladium-catalyzed hydroxycarbonylation of heteroaryl halides to corresponding carboxylic acids using acetic-formic anhydride in presence of Pd(OAc)2, dppf, and diisopropylethyl amine in dimethyl formamide at 80-90 C in excellent yields. Taylor & Francis Group, LLC.

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Benzofuran – Wikipedia,
Benzofuran | C8H3229O – PubChem

Application of 57319-65-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.57319-65-0, Name is 6-Aminoisobenzofuran-1(3H)-one, molecular formula is C8H7NO2. In a Article，once mentioned of 57319-65-0

A method was developed for the synthesis of 1-oxo-1H-isothiochromenes from 2-benzofuran-1(3H)-one (phthalide). 3-Bromo-6-chloro- and 3,6-dibromo-2- benzofuran-1(3H)-ones were prepared by the bromination of 6-chloro- and 6-bromo-2-benzofuran-1(3H)-ones and were converted by hydrolysis into 5-chloro- or 5-bromo-2-formylbenzoic acids. The condensation of these acids with rhodanine followed by recyclization gave 7-chloro- and 7-bromo-1-oxo-1H-isothiochromene- 3-carboxylic acids.

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Benzofuran – Wikipedia,
Benzofuran | C8H1409O – PubChem

Related Products of 1563-38-8, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 1563-38-8, Name is 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol,introducing its new discovery.

Compounds of general formula (I), wherein R1 selected from phenyl, pyridinyl, thiophenyl, furanyl, imidazolyl, and triazolyl; where each R1 phenyl ring and R1 heteroaromatic ring may optionally and independently be further substituted by 1, 2 or 3 substituents selected from straight and branched C1-C6 alkyl, NO2, CF3, C1-C6 alkoxy, chloro, fluoro, bromo, and iodo.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H2329O – PubChem

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. category: benzofuran, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 125-20-2, name is Thymolphthalein. In an article，Which mentioned a new discovery about 125-20-2

One of the options under development for carbon capture, utilization and storage (CCUS) is referred to as the Abo Akademi (AA) route, which is a two-stage route using serpentinite rock and ammonium sulphate to produce magnesium hydroxide that is subsequently carbonated in a gas-solid reactor. An issue for the process is to find a suitable way to precipitate and separate magnesium hydroxide and iron oxides from the obtained aqueous solution. Research presented in this paper will give some results from the separation of precipitated magnesium and iron oxides and hydroxides, as well as magnesium (hydro)carbonates (which are produced in the case where CO2 is fed to the solution at the same time). Experiments were done with analytical grade magnesium and iron sulphates as well as with serpentinite rock-derived magnesium and iron sulphate solutions. Inclined settlers were used and solutions were pumped into the settlers at different flow rates. Precipitation of the species was done either in a mixer before the solution was pumped to the settler or in the inclined settler itself. Most experiments were run at ambient temperature. Recirculation was used in some experiments in order to try to increase the precipitation and sedimentation efficiency. It was shown possible to achieve continuous separation of the solids from the suspensions. Increased temperature did not seem to affect settling of the magnesium hydroxide particles. Separation in inclined settlers would dictate very low pumping rates to avoid a too turbulent environment in the settling zone. Sedimentation was enhanced by applying wet (aqueous) carbonation thus achieving a magnesium (hydro)carbonate product with larger particle size than the suggested magnesium hydroxide separated according to the conventional AA route. Effort needs still to be put to optimizing the separation step in order to create a continuous flow combined with preceding process steps.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H4327O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Recommanded Product: Benzofuran-6-ol, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 13196-11-7, Name is Benzofuran-6-ol, molecular formula is C8H6O2

A series of 4-benzofuranyloxynicotinamide derivatives were identified to be novel, potent, and orally available TGR5 agonists. Among them, compound 9r had the highest potency in vitro (hTGR5 EC50 = 0.28 nM, mTGR5 EC 50 = 0.92 nM). Further in vivo studies disclosed that 9r could effectively lower the blood glucose, but meantime caused an increase in the gallbladder volume of mice. Subsequent research toward eliminating the gallbladder toxicity resulted in compound 19 with low permeability. Although the EC50 of mTGR5 of 19 was larger one order than that of 9r, it still had good glucose-lowing activity. Nevertheless, 19 also caused the adverse effects to the gallbladder. The drug levels detection disclosed that the concentration of 19 was only lower than that of 9r in plasma but was higher in bile and gallbladder tissue. This result indicated that low exposure in plasma could not guarantee low exposure in bile and gallbladder tissue, and thus resulting in the gallbladder toxicity of 19.

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Benzofuran – Wikipedia,
Benzofuran | C8H427O – PubChem