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Chemistry is traditionally divided into organic and inorganic chemistry. Product Details of 13196-11-7, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 13196-11-7

Described herein are compounds, including pharmaceutically acceptable salts thereof, methods of making such compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat, prevent or diagnose blood-based diseases, disorders or conditions.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H399O – PubChem

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A series of 4-benzofuranyloxynicotinamide derivatives were identified to be novel, potent, and orally available TGR5 agonists. Among them, compound 9r had the highest potency in vitro (hTGR5 EC50 = 0.28 nM, mTGR5 EC 50 = 0.92 nM). Further in vivo studies disclosed that 9r could effectively lower the blood glucose, but meantime caused an increase in the gallbladder volume of mice. Subsequent research toward eliminating the gallbladder toxicity resulted in compound 19 with low permeability. Although the EC50 of mTGR5 of 19 was larger one order than that of 9r, it still had good glucose-lowing activity. Nevertheless, 19 also caused the adverse effects to the gallbladder. The drug levels detection disclosed that the concentration of 19 was only lower than that of 9r in plasma but was higher in bile and gallbladder tissue. This result indicated that low exposure in plasma could not guarantee low exposure in bile and gallbladder tissue, and thus resulting in the gallbladder toxicity of 19.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H427O – PubChem

Reference of 13196-11-7, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.13196-11-7, Name is Benzofuran-6-ol, molecular formula is C8H6O2. In a article，once mentioned of 13196-11-7

3-(S)-Pyrimidin-5-yl-9-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl)-nonanoic acid (5e) and 3-(S)-(methylpyrimidin-5-yl)-9-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl)-nonanoic acid (5f) were identified as potent and selective antagonists of the alpha(v)beta(3) receptor. These compounds have excellent in vitro profiles (IC(50) = 0.07 and 0.08 nM, respectively), significant unbound fractions in human plasma (6 and 4%), and good pharmacokinetics in rat, dog, and rhesus monkey. On the basis of the efficacy shown in an in vivo model of bone turnover following once-daily oral administration, these two compounds were selected for clinical development for the treatment of osteoporosis.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H414O – PubChem

Chemistry is traditionally divided into organic and inorganic chemistry. name: Benzofuran-6-ol, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 13196-11-7

Methods of preparation and purification of a compound, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA -1 mediated diseases are also disclosed.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H406O – PubChem

Related Products of 13196-11-7, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.13196-11-7, Name is Benzofuran-6-ol, molecular formula is C8H6O2. In a article，once mentioned of 13196-11-7

The invention discloses a PD – 1/PD – L1 small molecule inhibitor and its preparation and use. In particular, the invention discloses the structure of a compound represented by the formula L, its stereoisomer or a tautomer thereof, or a pharmaceutically acceptable salt, hydrate or solvate, specific defined in the specification. Also discloses the use of such compounds in inhibiting PD – 1/PD – L1 has excellent effect. (by machine translation)

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H404O – PubChem

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. SDS of cas: 13196-11-7, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 13196-11-7, name is Benzofuran-6-ol. In an article，Which mentioned a new discovery about 13196-11-7

The invention provides a compound of formula (I) indicated by the nucleoside phosphorus amide compound, and the compound as an anti-viral drug use. The invention of the formula (I) compound can inhibit the replication of virus RNA, can be used as a hepatitis c virus (HCV) NS5B polymerase inhibitors. The compounds of this invention having a NS5B polymerase inhibitory effect at the same time, its small hepatocyte toxicity. (by machine translation)

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H402O – PubChem

Related Products of 13196-11-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.13196-11-7, Name is Benzofuran-6-ol, molecular formula is C8H6O2. In a Article，once mentioned of 13196-11-7

Efficient stereoselective syntheses of 5- and 6-[2,3]-dihydrobenzofuran beta-amino acids are described. These 3-aryl beta-amino acids are aspartic acid mimetics that are structurally related to known benzodioxole systems. In many cases, the benzodioxole can inhibit and induce cytochrome P-450; neither of these dihydrobenzofuran beta-amino esters is a potent inhibitor of several human P-450 enzymes. (C) 2000 Elsevier Science Ltd.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H413O – PubChem

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Recommanded Product: 13196-11-7, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 13196-11-7, name is Benzofuran-6-ol. In an article，Which mentioned a new discovery about 13196-11-7

Benzofuran derivatives and benzofuransare presented as scaffolds in complex molecules and have attracted much attention and prevalent interest due to their interesting biological activity. They also exist in several numbers of naturally occurring compounds and exhibiting biological activity. In this review, we will try to underscore the reactivity of benzofurans through comprehension and giving a full perspective to the readers.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H417O – PubChem

Synthetic Route of 13196-11-7, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 13196-11-7, molcular formula is C8H6O2, introducing its new discovery.

A novel ligand-free palladium-catalyzed C-2 arylation of benzofurans has been developed using N?-acyl arylhydrazines as the coupling partners and TEMPO as an oxidant. This protocol features a wide functional-group tolerance and highly regioselective products with good to excellent yields.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 13196-11-7 is helpful to your research. Synthetic Route of 13196-11-7

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H410O – PubChem

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An optimized process for the preparation of 6-hydroxybenzofuran is described. This process consists of three steps: the reaction of 2-hydroxy-4-methoxybenzaldehyde with chloroacetic acid, the formation of the 6-methoxybenzofuran in acetic anhydride, and the demethylation with sodium 1-dodecanethiolate to afford the desired product. The entire process is safe, cost effective, environmentally benign, and scalable. A production scale of over 2.6 kg product was achieved in good overall yield.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H423O – PubChem