Quality Control of (R)-Ethyl 4-chloro-3-hydroxybutanoate. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: (R)-Ethyl 4-chloro-3-hydroxybutanoate, is researched, Molecular C6H11ClO3, CAS is 90866-33-4, about Synthesis of negamycin and its derivatives as potential therapeutic agents for Duchenne muscular dystrophy.
A symposium report. A total synthesis of (+)-negamycin, a dipeptidic antibiotic containing a hydrazine peptide bond and its derivatives, using ah asym. Michael addition of chiral methoxybornyl-10-benzylamine as the pivotal step, is reported. This compound was successfully synthesized with an overall yield of 26% in 13 steps and exhibited a similar biol. activity to gentamicin in restoring dystrophin expression in skeletal and cardiac muscles of max mice, an animal model of Duchenne muscular dystrophy.
Compounds in my other articles are similar to this one((R)-Ethyl 4-chloro-3-hydroxybutanoate)Quality Control of (R)-Ethyl 4-chloro-3-hydroxybutanoate, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem