Name: (R)-Ethyl 4-chloro-3-hydroxybutanoate. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: (R)-Ethyl 4-chloro-3-hydroxybutanoate, is researched, Molecular C6H11ClO3, CAS is 90866-33-4, about Sequential pretreatment of bamboo shoot shell and biosynthesis of ethyl (R)-4-chloro-3-hydroxybutanoate in aqueous-butyl acetate media. Author is Gu, Ting; Wang, Bingqian; Zhang, Ziwei; Wang, Ziteng; Chong, Ganggang; Ma, Cuiluan; Tang, Yajie; He, Yucai.
Organic solvent of low log P value could be used to remove hemicellulose and lignin in bamboo shoot shell (BSS). Combination pretreatment with biocompatible Bu acetate (Log P = 1.7, 10 v%) and dilute sodium acetate (NaAc, 2 wt%) was chosen to pretreat BSS by autoclaving (110°C, 40 min, pretreatment severity factor Log R0 = 3.2) for enhancing enzymic in situ saccharification of BSS. In the BSS-hydrolyzates, soluble sugars (500 mM glucose, 419.3 mM xylose, 29.9 mM cellobiose and 129.4 mM arabinose) significantly increased the intracellular NADH content and the biocatalytic activity of recombinant E. coli CCZU-H15 whole-cells when 500 mM Et 4-chloro-3-oxobutanoate (COBE) were biol. converted. Et (R)-4-chloro-3-hydroxybutanoate [(R)-CHBE] was obtained at 98.5% yield without extra addition of cofactor. In summary, this strategy involving combination pretreatment, enzymic hydrolysis without washing/detoxification, and bioreduction of COBE has high potential application for the effective biosynthesis of (R)-CHBE.
In some applications, this compound(90866-33-4)Name: (R)-Ethyl 4-chloro-3-hydroxybutanoate is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem