Category: 50551-57-0

Application of 50551-57-0, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 50551-57-0, Name is Ethyl 6-methoxybenzofuran-2-carboxylate, molecular formula is C12H12O4. In a Article，once mentioned of 50551-57-0

Modification of the 1,4-benzodioxan ring present in RX 781094 (1) has not previously been considered.This paper describes a number of analogues of this ring system, including compounds in which one of the oxygen atoms has been replaced by a methylene group and also those in which the ring size has been changed to give, for example, furan and thiophene derivatives.The dihydroxybenzofuranylimidazoline compound 7 is the only analogue possesing presynaptic antagonist potency and selectivity comparable to that of 1.In view of this result, a number of derivatives was prepared to determine the structure-activity relationships within this series.Many derivatives, as well as the parent compound 7, were found to possess presynaptic alpha2-adrenoreceptor antagonist and postsynaptic alpha1-adrenoreceptor partial agonist properties.Two of the selective presynaptic antagonists,13 and 14, possess greater potency and selectivity than that possessed by 1.The 5-chloro derivative 25 is twice as potent as 1 after oral administration but only about half as potent when given intravenously.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 50551-57-0. In my other articles, you can also check out more blogs about 50551-57-0

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3794O – PubChem

Application of 50551-57-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.50551-57-0, Name is Ethyl 6-methoxybenzofuran-2-carboxylate, molecular formula is C12H12O4. In a Article，once mentioned of 50551-57-0

1-Methyl-3-ethyl imidazolium bromide [meim]Br/basic alumina (Al2O3) has been found to promote the cyclocondensation of chloroacetone/chloroethyl acetate with salicylaldehydes under conventional as well as microwave irradiation to yield benzofuran derivatives.

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 50551-57-0, and how the biochemistry of the body works.Application of 50551-57-0

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3801O – PubChem

Synthetic Route of 50551-57-0, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 50551-57-0, Name is Ethyl 6-methoxybenzofuran-2-carboxylate, molecular formula is C12H12O4. In a Article，once mentioned of 50551-57-0

The BMP pathway is a promising new target for the design of therapeutic agents for the treatment of low bone mass. To enrich our understanding of SAR and based on our previously concluded structure-effect relationship, 23 derivatives were prepared in this work. The synthesis, up-regulating activities on BMP-2 expression, and bone loss prevention efficacies of these compounds in rats with glucocorticoid-induced osteoporosis are presented. The bone histology of the tested rats assessed through light microscopy showed that compounds 1, 21, 35, and 38 significantly increased the trabecula compared with the model group, and the trabecula of the groups treated with 8a was similar to that obtained with raloxifene and alfacalcidol. The compounds exhibited potential for development as anabolic agents.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 50551-57-0. In my other articles, you can also check out more blogs about 50551-57-0

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3802O – PubChem

Synthetic Route of 50551-57-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.50551-57-0, Name is Ethyl 6-methoxybenzofuran-2-carboxylate, molecular formula is C12H12O4. In a Patent，once mentioned of 50551-57-0

The present invention provides an aminostyrylbenzofuran compound of Formula (I), and a pharmaceutical composition comprising same. The pharmaceutical composition of the present invention comprising the compound of Formula (I), a pharmaceutically acceptable salt, an isomer, a hydrate, and a solvate thereof as an active ingredient can be useful for the prevention and treatment of degenerative brain diseases caused by accumulation of beta-amyloid.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 50551-57-0

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3790O – PubChem

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Formula: C12H12O4, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 50551-57-0, name is Ethyl 6-methoxybenzofuran-2-carboxylate. In an article，Which mentioned a new discovery about 50551-57-0

The first total chemical synthesis of a cis-syn furan-side photoproduct between a psoralen derivative and thymidine is described. The key step in the synthesis was an intramolecular [2 + 2] photocycloaddition, which directed the stereochemical course of the reaction to afford a product equivalent to that formed when a psoralen molecule is allowed to react at a 5′-TpA-3′ site in DNA. A model system consisting of a simple benzofuranyl acid tethered to the 5′ hydroxyl of thymidine showed that it was possible to bias the stereochemical outcome of the photochemical reaction in favor of the desired cis-syn product. Further refinement of the model system allowed for the elaboration of a benzofuran-thymidine photoproduct into a cis-syn 2-carbomethoxypsoralen furan-side thymidine monoadduct. The stereochemistry of all photoproducts as established by NMR and CD spectroscopy indicated that the cycloadditions occurred on the 3′ face of thymine, the equivalent of a psoralen monoadduct in a 5′-TpA-3′ site in DNA. Previously, the inability to program the sequence context of psoralen-DNA adducts has constrained certain biological studies, such as experiments aimed at deciphering the transcriptional effects of adducts at TATA sites. This method is a key step toward overcoming that problem.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 50551-57-0, help many people in the next few years.Formula: C12H12O4

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3798O – PubChem