HPLC of Formula: 50551-57-0On October 1, 2010 ,《Novel imidazoline compounds as partial or full agonists of D2-like dopamine receptors inspired by I2-imidazoline binding sites ligand 2-BFI》 was published in Bioorganic & Medicinal Chemistry. The article was written by Giorgioni, Gianfabio; Ambrosini, Dario; Vesprini, Cristian; Hudson, Alan; Nasuti, Cinzia; Di Stefano, Antonio; Sozio, Piera; Ciampi, Osele; Costa, Barbara; Martini, Claudia; Carrieri, Antonio; Carbonara, Giuseppe; Enzensperger, Christoph; Pigini, Maria. The article contains the following contents:
Based on the well known biol. versatility of the imidazoline nucleus, we prepared the novel derivatives 3a-k inspired by 2-BFI scaffold to assess imidazoline mols. as D2-like dopamine receptor ligands. Conservative chem. modifications of the lead structure, such as the introduction of an hydroxy group in the aromatic ring alone or associated with N-benzyl substitution, provided partial (3f)(I) or nearly full (3e and 3h) agonists, all endowed with D2-like potency comparable to that of dopamine. The experimental part of the paper was very detailed, including the reaction process of Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0HPLC of Formula: 50551-57-0)
Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0) belongs to benzofurans.HPLC of Formula: 50551-57-0Benzofurans containing one furan ring that have been implicated as psychoactive recreational drugs include 6-(2-aminopropyl)benzofuran (6-APB), 5-(2-aminopropyl)benzofuran (5-APB), 5-(2-ethylaminopropyl)benzofuran (5-EAPB), and 5-methylaminopropylbenzofuran (5-MAPB).
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem