COA of Formula: C12H12O4On October 15, 2008 ,《Aminostyrylbenzofuran derivatives as potent inhibitors for Aβ fibril formation》 was published in Bioorganic & Medicinal Chemistry Letters. The article was written by Byun, Ji Hun; Kim, HyeYun; Kim, YoungSoo; Mook-Jung, Inhee; Kim, Dong Jin; Lee, Won Koo; Yoo, Kyung Ho. The article contains the following contents:
The synthesis of a novel series of aminostyrylbenzofurans I (R1, R2 = H, Br, Cl, F, I, OH, OMe; R3 = NH2, NHMe, NMe2; R4 = H, OMe) and their inhibitory activities for Aβ fibril formation were described. All the synthesized compounds were evaluated by thioflavin T (ThT) assay and displayed potent inhibitory activities for Aβ fibril formation. Among them, compounds I (R1 = R4 = H; R2 = OMe; R3 = NMe2) and I (R1 = OMe, R2 = R4 = H; R3 = NHMe) exhibited excellent inhibitory activities (IC50 = 0.07 and 0.08 μM, resp.) than those of Curcumin (IC50 = 0.80 μM) and IMSB (IC50 = 8.00 μM) as reference compounds Both compounds were selected as promising candidates for further biol. evaluation. In the part of experimental materials, we found many familiar compounds, such as Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0COA of Formula: C12H12O4)
Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0) belongs to benzofurans.COA of Formula: C12H12O4Benzofurans containing one furan ring that have been implicated as psychoactive recreational drugs include 6-(2-aminopropyl)benzofuran (6-APB), 5-(2-aminopropyl)benzofuran (5-APB), 5-(2-ethylaminopropyl)benzofuran (5-EAPB), and 5-methylaminopropylbenzofuran (5-MAPB).
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem