A new application about Ethyl 6-methoxybenzofuran-2-carboxylate

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 50551-57-0. In my other articles, you can also check out more blogs about 50551-57-0

Application of 50551-57-0, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 50551-57-0, Name is Ethyl 6-methoxybenzofuran-2-carboxylate, molecular formula is C12H12O4. In a Article,once mentioned of 50551-57-0

Modification of the 1,4-benzodioxan ring present in RX 781094 (1) has not previously been considered.This paper describes a number of analogues of this ring system, including compounds in which one of the oxygen atoms has been replaced by a methylene group and also those in which the ring size has been changed to give, for example, furan and thiophene derivatives.The dihydroxybenzofuranylimidazoline compound 7 is the only analogue possesing presynaptic antagonist potency and selectivity comparable to that of 1.In view of this result, a number of derivatives was prepared to determine the structure-activity relationships within this series.Many derivatives, as well as the parent compound 7, were found to possess presynaptic alpha2-adrenoreceptor antagonist and postsynaptic alpha1-adrenoreceptor partial agonist properties.Two of the selective presynaptic antagonists,13 and 14, possess greater potency and selectivity than that possessed by 1.The 5-chloro derivative 25 is twice as potent as 1 after oral administration but only about half as potent when given intravenously.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 50551-57-0. In my other articles, you can also check out more blogs about 50551-57-0

Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3794O – PubChem