Tag: 125-20-2

Simple exploration of 125-20-2

125-20-2 Thymolphthalein 31316, abenzofuran compound, is more and more widely used in various.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.125-20-2,Thymolphthalein,as a common compound, the synthetic route is as follows.

preparation steps are: thymolphtaleine (5) (4.3 g, 10 mmol), TBAHS (3.4 g, 10 mmol), acetobromo-alpha-D-glucuronic acid methyl ester (4) (4.0 g, 10 mmol) dissolved in 30 ml of dichloromethane and cooled to 10 C, 30 ml of 1N potassium carbonate aqueous solution was added and then stirred at room temperature for 3 hours, and the mixture was separated and dried over anhydrous sodium sulfate. The organic phase was concentrated to dryness to give thymolphtaleine-alpha-acetyl-D-glucuronic acid methyl ester (6) (yield: 3.4 g, yield 46.7%).

125-20-2 Thymolphthalein 31316, abenzofuran compound, is more and more widely used in various.

Reference£º
Patent; Guangdong Younide Biological Technology Co., Ltd.; Sai Chi Bio-technology (Shanghai) Co., Ltd.; Su Hongwen; Lai Hua; Liang Weiye; Liu Zhiwen; (7 pag.)CN108129530; (2018); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem

New learning discoveries about 125-20-2

As the paragraph descriping shows that 125-20-2 is playing an increasingly important role.

125-20-2, Thymolphthalein is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

preparation method as follow: thymolphthalein (4.3 g, 10 mmol), TBAHS (3. 4 g, 10 mmol), 2-acetamido-3,4,6 -tri-O-acetyl -2-deoxy- A -D-glucopyranoside (3.65g, 10 mmol) dissolved in dichloromethane and cooled down to 10 degrees. After adding 30 ml of 1N potassium carbonate aqueous solution, the mixture was stirred at room temperature for 3 hours, and the mixture was separated and dried over anhydrous sodium sulfate. The organic phase is concentrated to dry column to obtain thymolphthalein-N-acetyl-3,4,6-O-triacetyl-beta-D-glucapyranoside (Yield 4.5 g, yield 61.2%).

As the paragraph descriping shows that 125-20-2 is playing an increasingly important role.

Reference£º
Patent; Guangdong Younide Biological Technology Co., Ltd.; Sai Chi Bio-technology (Shanghai) Co., Ltd.; Su Hongwen; Lai Hua; Liang Weiye; Liu Zhiwen; (6 pag.)CN108218926; (2018); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem