With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.125-20-2,Thymolphthalein,as a common compound, the synthetic route is as follows.
preparation steps are: thymolphtaleine (5) (4.3 g, 10 mmol), TBAHS (3.4 g, 10 mmol), acetobromo-alpha-D-glucuronic acid methyl ester (4) (4.0 g, 10 mmol) dissolved in 30 ml of dichloromethane and cooled to 10 C, 30 ml of 1N potassium carbonate aqueous solution was added and then stirred at room temperature for 3 hours, and the mixture was separated and dried over anhydrous sodium sulfate. The organic phase was concentrated to dryness to give thymolphtaleine-alpha-acetyl-D-glucuronic acid methyl ester (6) (yield: 3.4 g, yield 46.7%).
125-20-2 Thymolphthalein 31316, abenzofuran compound, is more and more widely used in various.
Reference£º
Patent; Guangdong Younide Biological Technology Co., Ltd.; Sai Chi Bio-technology (Shanghai) Co., Ltd.; Su Hongwen; Lai Hua; Liang Weiye; Liu Zhiwen; (7 pag.)CN108129530; (2018); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem