641-70-3, 3-Nitrophthalic anhydride is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A round bottom flask was charged with a solution of glacial acetic acid (75 ml) and alpha-amino glutarimide hydrochloride (8.5 g). Sodium acetate anhydrous (4.5 g) was added lot-wise to the solution at 25 C. to 30 C. followed by addition of 3-nitro phthalic anhydride (log) at the same temperature. The reaction mixture was stirred at 118 C. for 18 hr. After the completion of reaction, the reaction mass was cooled to 60 C. and the solvent was distilled off under vacuum to get the residue. To the residue obtained, water (100 ml) was added; the mixture was stirred for 1 hr at 25 C. to 30 C. and the mass filtered. The wet cake obtained was slurried with water (100 ml*2), filtered and dried in an air tray dryer until the water content was less than 0.5% to afford 2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione (14 g). Yield: 89.7%, Purity: 98%.
As the paragraph descriping shows that 641-70-3 is playing an increasingly important role.
Reference£º
Patent; Apicore US LLC; Kovi, Ravishanker; Bobbili, Veerabhadra Rao; Kannapan, Jayaraman; (13 pag.)US2017/260157; (2017); A1;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem