Category: benzofurans

Synthetic Route of 1563-38-8, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 1563-38-8, molcular formula is C10H12O2, introducing its new discovery.

The present invention provides a novel organophosphoric acid ester represented by the following formula, a process for its production and a pesticidal composition containing this ester as an active ingredient: STR1 where R1 is an alkyl group, R2 is an alkyl group or a thioalkyl group, each of R3, R4 and R5 is a hydrogen atom, a halogen atom, an alkylthio group, a nitro group, a cyano group, an alkyl group, an alkylsulfinyl group, an alkylsulfonyl group or a trifluoromethyl group, and X is an oxygen atom or a sulfur atom.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 1563-38-8 is helpful to your research. Synthetic Route of 1563-38-8

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H2300O – PubChem

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 26238-14-2, name is 5-(Trifluoromethyl)isobenzofuran-1,3-dione, introducing its new discovery. Recommanded Product: 26238-14-2

3-Nitroindenoisoquinoline human topoisomerase IB (Top1) poisons have potent antiproliferative effects on cancer cells. The undesirable nitro toxicophore could hypothetically be replaced by other functional groups that would retain the desired biological activities and minimize potential safety risks. Eleven series of indenoisoquinolines bearing 3-nitro bioisosteres were synthesized. The molecules were evaluated in the Top1-mediated DNA cleavage assay and in the National Cancer Institute’s 60 cell line cytotoxicity assay. The data reveal that fluorine and chlorine may substitute for the 3-nitro group with minimal loss of Top1 poisoning activity. The new information gained from these efforts can be used to design novel indenoisoquinolines with improved safety.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3663O – PubChem

24410-59-1, Name is 5-Fluorobenzofuran, belongs to benzofurans compound, is a common compound. Computed Properties of C8H5FOIn an article, once mentioned the new application about 24410-59-1.

The present invention provides a novel 1H-indazole compound having an excellent JNK inhibitory action. More specifically, it provides a compound represented by the following formula, a salt thereof or a hydrate of them. Wherein R1 is a C6-C14 aromatic cyclic hydrocarbon group etc.; R2, R4 and R5 each independently represent a hydrogen atom, a halogen atom, a cyano group etc.; L is a single bond, or a C1-C6 alkylene group etc.; X is a single bond, or a group represented by -CO-NH- or -NH-CO-, etc.; and Y is a C3-C8 cycloalkyl group, a C6-C14 aromatic cyclic hydrocarbon group or a 5- to 14-membered aromatic heterocyclic group etc.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H557O – PubChem

Synthetic Route of 10242-10-1, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 10242-10-1, 5-Chlorobenzofuran-2-carboxylic acid, introducing its new discovery.

Hypoglycemic 5-chromanyl, 2,3-dihydro-5-benzo[b]furanyl, 5-pyridyl, 5-quinolyl, 5-pyrrolyl, 5-indolyl, 5-thiazolyl, 5-oxazolyl, 5-isothiazolyl and 5-isoxazolyl oxazolidine-2,4-diones and the pharmaceutically acceptable salts thereof; certain 3-acylated derivatives thereof; a method of treating hyperglycemic animals therewith; and intermediates useful in the preparation of said compounds.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 10242-10-1. In my other articles, you can also check out more blogs about 10242-10-1

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3176O – PubChem

4265-16-1, Name is Benzo[b]furan-2-carboxaldehyde, belongs to benzofurans compound, is a common compound. Quality Control of Benzo[b]furan-2-carboxaldehydeIn an article, once mentioned the new application about 4265-16-1.

The present invention provides a novel pyridylaminoacetic acid compound represented by the following formula (1): (wherein R1, R2, R3, Y and Z are as defined in the description and claims), or a pharmacologically acceptable salt thereof. The pyridylaminoacetic acid compound has EP2 agonistic action and is therefore useful as a therapeutic and/or prophylactic agent for respiratory diseases such as asthma or chronic obstructive pulmonary disease.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H709O – PubChem

125-20-2, Name is Thymolphthalein, belongs to benzofurans compound, is a common compound. Safety of ThymolphthaleinIn an article, once mentioned the new application about 125-20-2.

THE modification MAIN objective with various of this types research of water-based is to improve polymer ink latexes printability during paper of papers manufacturing via their process. In order to achieve this target, various types of styrene-acrylate polymer latexes were used for modification of different types of papers. Styrene-acrylate latexes were prepared via emulsion polymerization of styrene with various acrylate monomers using emulsion polymerization technique. The effect of different emulsifying agents on the properties of the prepared emulsions was studied. The obtained results showed a significant improvement in degree of gloss and ink density on the polymer-coated papers which positively affect the ink ability, and ink holding properties of the modified paper. In addition, ink gloss and ink density of the coated papers improved with increasing the concentration of modifying latexes containing TexaponP as emulsifier. These promising results open the way to use polymer latexes in treatment of documented value which can be used in stabilization of disappearing ink on paper leading to prevent forgery.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H4301O – PubChem

Application of 50551-57-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.50551-57-0, Name is Ethyl 6-methoxybenzofuran-2-carboxylate, molecular formula is C12H12O4. In a Article，once mentioned of 50551-57-0

1-Methyl-3-ethyl imidazolium bromide [meim]Br/basic alumina (Al2O3) has been found to promote the cyclocondensation of chloroacetone/chloroethyl acetate with salicylaldehydes under conventional as well as microwave irradiation to yield benzofuran derivatives.

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 50551-57-0, and how the biochemistry of the body works.Application of 50551-57-0

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3801O – PubChem

Chemistry is traditionally divided into organic and inorganic chemistry. category: benzofuran, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 4265-25-2

Cathodic reduction of 3-bromochromenes led to a ring-opening reaction yielding o-allenylphenyl acetates.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H46O – PubChem

Related Products of 805250-17-3, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 805250-17-3, molcular formula is C11H12O4, introducing its new discovery.

The free fatty acid receptor 1 (FFA1) and peroxisome proliferator-activated receptors (PPARs) have attracted interest as potent targets for the treatment of metabolic syndrome such as type 2 diabetes. Based on the hypothesis that the dual agonists of PPARs and FFA1 would act as insulin sensitizers and secretagogues by simultaneous activation of PPARs and FFA1, we developed the design strategy to obtain dual PPARs/FFA1 agonist by hybrid FFA1 agonist 1 with PPARdelta agonist 2 in consideration of their structural similarity. As expected, systematic exploration of structure-activity relationship and molecular modeling, results in the discovery of lead compound 15, a pan agonist with relative balanced activities between FFA1, PPARgamma and PPARdelta. The dose-response relationship studies suggested that the pan agonist 15 suppressed the excursion of blood glucose levels in a dose-dependent manner. During a 5-days treatment in ob/ob mice, the pan agonist 15 (100 mg/kg) revealed sustained hypoglycemic effect, even proximity to the most advanced FFA1 agonist (TAK-875, 40 mg/kg), which might be attributed to its pan PPARs/FFA1 activities to simultaneous regulate the mechanism of insulin secretion and resistance. These positive results suggest that the dual PPARs/FFA1 agonists such as lead compound 15 might be novel therapeutic strategy to modulate the complex pathological mechanisms of type 2 diabetes.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 805250-17-3 is helpful to your research. Related Products of 805250-17-3

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3566O – PubChem

Chemistry is traditionally divided into organic and inorganic chemistry. Application In Synthesis of 2-Bromobenzofuran, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 54008-77-4

Methods for the conversion of aliphatic acids to alkyl halides have progressed significantly over the past century, however, the analogous decarboxylative bromination of aromatic acids has remained a longstanding challenge. The development of efficient methods for the synthesis of aryl bromides is of great importance as they are versatile reagents in synthesis and are present in many functional molecules. Herein we report a transition metal-free decarboxylative bromination of aromatic acids. The reaction is applicable to many electron-rich aromatic and heteroaromatic acids which have previously proved poor substrates for Hunsdiecker-type reactions. In addition, our preliminary mechanistic study suggests that radical intermediates are not involved in this reaction, which is in contrast to classical Hunsdiecker-type reactivity. Overall, the process demonstrates a useful method for producing valuable reagents from inexpensive and abundant starting materials.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3257O – PubChem