Category: benzofurans

Nath, Sarbasri published the artcileFast Synthesis of Benzofurans from Coumarins, Application In Synthesis of 50551-63-8, the main research area is coumarin zinc oxide catalyst microwave irradiation ring contraction; benzofuran preparation green chem.

A new solid support, Zinc oxide was used as a green catalyst for the ring contraction of coumarins to benzofurans. Employing microwave induced synthesis whenever possible, minimizing the use of toxic solvents. Benzofurans was achieved from coumarins by ring contraction reaction in single step. Microwave irradiation was used to shorten the reaction time and to improve the yield.

Journal of Ultra Chemistry published new progress about Benzofurans Role: SPN (Synthetic Preparation), PREP (Preparation). 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, Application In Synthesis of 50551-63-8.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Zhang, Bang-Le published the artcileA new efficient method for the total synthesis of linear furocoumarins, Product Details of C9H8O2, the main research area is furocoumarin total synthesis; psoralen total synthesis; benzofuran preparation; nitroalkyl phenol Nef oxidation intramol cyclocondensation.

A new efficient method for the synthesis of linear furocoumarins by a Nef reaction and intramol. cyclocondensation in one pot results in the construction of a benzofuran ring. This method provides a new strategy to furnish the benzofuran framework easily, and also allows the convenient synthesis of furocoumarin derivatives with different substituents on the coumarin ring by a subsequent Pechmann reaction. This strategy has also been applied to the preparation of four addnl. benzofuran derivatives

Synlett published new progress about Coumarins Role: SPN (Synthetic Preparation), PREP (Preparation). 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, Product Details of C9H8O2.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Fang, Huaquan published the artcileA Pincer Ruthenium Complex for Regioselective C-H Silylation of Heteroarenes, Quality Control of 50551-63-8, the main research area is pincer ruthenium complex catalyst regioselective silylation heteroarene; heteroaryl silane preparation regioselective Hiyama Denmark coupling iodobenzene.

A pincer Ru(II) catalyst for the highly efficient undirected silylation of O- and S-heteroarenes with (TMSO)2MeSiH and Et3SiH is described, producing heteroarylsilanes with exclusive C2-regioselectivity, good functional-group tolerance, and high turnover numbers (up to 1960). The synthetic utility of the silylated products is demonstrated by Pd-catalyzed Hiyama-Denmark cross-coupling under mild conditions. One-pot, two-step silylation and coupling procedures have been also developed.

Organic Letters published new progress about Aryl iodides Role: RCT (Reactant), RACT (Reactant or Reagent). 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, Quality Control of 50551-63-8.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Henry, Martyn C. published the artcileSynthesis of Benzo[b]furans by Intramolecular C-O Bond Formation Using Iron and Copper Catalysis, Category: benzofurans, the main research area is benzofuran preparation regioselective; aryl alkyl ketone halogenation arylation iron copper catalyst.

One-pot processes for the synthesis of benzo[b]furans from 1-aryl- or 1-alkylketones using nonprecious transition metal catalysts have been developed. Regioselective iron(III)-catalyzed halogenation of the aryl ring, followed by iron- or copper-catalyzed O-arylation allowed the synthesis of various structural analogs, including the benzo[b]furan-derived natural products corsifuran C, moracin F, and caleprunin B.

Organic Letters published new progress about Acetamides Role: RCT (Reactant), RACT (Reactant or Reagent). 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Category: benzofurans.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Graham, Samuel L. published the artcileTopically active carbonic anhydrase inhibitors. 3. Benzofuran- and indole-2-sulfonamides, HPLC of Formula: 50551-63-8, the main research area is benzofuransulfonamide preparation carbonic anhydrase inhibition; indolesulfonamide preparation carbonic anhydrase inhibition; carbonic anhydrase inhibition benzofuransulfonamide indolesulfonamide; ocular hypotensive benzofuransulfonamide indolesulfonamide; glaucoma treatment indolesulfonamide benzofuransulfonamide.

Derivatives of 2-benzofuran- and 2-indolesulfonamide (e.g., I, II) were prepared for evaluation as topically active ocular hypotensive agents. These compounds were excellent inhibitors of carbonic anhydrase and lowered intraocular pressure in a rabbit model of ocular hypertension. However, their development for clin. use was precluded because they cause dermal sensitization in guinea pigs. A correlation between electrophilicity, as assessed by in vitro reactivity with reduced glutathione, and dermal sensitization potential was further documented.

Journal of Medicinal Chemistry published new progress about Allergens Role: RCT (Reactant), RACT (Reactant or Reagent). 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, HPLC of Formula: 50551-63-8.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Zhou, Muxing published the artcileChiral Bicyclic Imidazole-Catalyzed Acylative Dynamic Kinetic Resolution for the Synthesis of Chiral Phthalidyl Esters, Computed Properties of 52010-22-7, the main research area is acylative dynamic kinetic resolution hydroxyphthalide bicyclic imidazole catalyst; enantioselective acylation hydroxyphthalide dynamic kinetic resolution; phthalidyl ester prodrug preparation acylative dynamic kinetic resolution; bicyclic imidazole; dynamic kinetic resolution; enantioselective acylation; organocatalyst; phthalidyl ester prodrugs.

Utilizing a chiral bicyclic imidazole organocatalyst, I, and adopting a continuous injection process, an alternative route has been developed for the efficient synthesis of chiral phthalidyl ester prodrugs via dynamic kinetic resolution of 3-hydroxyphthalides through enantioselective acylation (up to 99% ee). The computational studies suggest a general base catalytic mechanism differing from the widely accepted nucleophilic catalytic mechanism. The structure anal. of the key transition states shows that the CH-π interaction, and not the previously considered cation/π-π interactions between the catalyst and substrate, is the dominant factor giving rise to the observed stereocontrol.

Angewandte Chemie, International Edition published new progress about Acylation catalysts (stereoselective, kinetic resolution). 52010-22-7 belongs to class benzofurans, name is 4-Chlorophthalide, and the molecular formula is C8H5ClO2, Computed Properties of 52010-22-7.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem