On September 25, 2008, Cai, Xiong; Qian, Changgeng; Zhai, Haixiao published a patent.Computed Properties of 60770-67-4 The title of the patent was Preparation of imidazo[4,5-c]pyridine derivatives as HSP90 inhibitors. And the patent contained the following:
Title compounds represented by the formula I [wherein U = N or CH; W = H, halo, amino, etc.; X = absent, O, S, etc.; Y = independently H, halo, NO2, CN or alkyl; Z = (alkylcarbonyl)amino or (di)alkylamino; Q = (un)substituted (hetero)aryl or (Hetero)cycloalkyl; V = H, (un)substituted aryl, alkenyl, etc.; and geometric isomers, enantiomers, diastereomers, racemates, pharmaceutically acceptable salts, prodrugs and solvates thereof] were prepared as HSP90 inhibitors. For example, II was provided in a multi-step synthesis starting from N-(4-pentynyl)phthalimide. I were tested for inhibiting HSP90 chaperone activity in vitro assay and HSP90 competition binding (Fluorescence Polarization) assay. Thus, I and their pharmaceutical compositions are useful as HSP90 inhibitors for the treatment of HSP90 related diseases and disorders such as cancer, an autoimmune disease, or a neurodegenerative disease. The experimental process involved the reaction of 5-Iodobenzofuran(cas: 60770-67-4).Computed Properties of 60770-67-4
The Article related to imidazopyridine preparation hsp90 inhibitor cancer autoimmune neurodegenerative disease treatment, Heterocyclic Compounds (More Than One Hetero Atom): Imidazoles and other aspects.Computed Properties of 60770-67-4
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem