Month: November 2022

Olalere, Olusegun Abayomi published the artcileMicrostructural and microchemical characterization of valorized cola nitida pod wastes, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, the publication is Chemical Data Collections (2020), 100356, database is CAplus.

The inherent environmental effects of the accumulated kola nut pod waste products have become a subject of discussion among many researchers. The need then arises for their alternative use as nutraceutical bioproducts. The phys. and chem. anal. techniques are often required for the standardization of these bioproducts in order to determine and maintain their quality characteristics. The dataset presented in this study provided information on the chem. profile, physisorption and thermo-anal. screening of Cola nut pod extracts Six sets of physicochem. methods were employed to characterize the phenolic extracts The result obtained clearly revealed the presence of two-hundred and fifty-five phenolic bioactive. Also presented was the thermal stability, morphol. and microstructural surface area configuration of the Cola nitida pod extracts The information obtained from this study could be used in determining the quality of food wastes bioproducts in nutria-pharmaceutical applications.

Chemical Data Collections published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Farmer, Jennifer L. published the artcileSolvent Choice and Kinetic Isotope Effects (KIEs) Dramatically Alter Regioselectivity in the Directed ortho Metalation (DoM) of 1,5-Dichloro-2,4-dimethoxybenzene, Quality Control of 69626-75-1, the publication is Chemistry – A European Journal (2015), 21(5), 1888-1893, database is CAplus and MEDLINE.

The regioselective formation of the 6-lithio derivative of 1,5-dichloro-2,4-dimethoxybenzene (i.e., 12) by directed ortho metalation (DoM) with nBuLi in THF is described. Although literature reports suggest direct deprotonation at C6, time-course and labeling studies revealed that deprotonation rather occurs exclusively at C3 followed by isomerization of the anion to C6. By contrast, when DoM was performed in Et₂O, deprotonation again occurred selectively at C3, but now no isomerization occurs, and electrophilic capture produces the regioisomer of that produced in THF. In these labeling studies, deuterium has an enormous kinetic isotope effect (KIE) that suppresses not only the original DoM reaction at C3 when deuterium is present there, but also suppresses isomerization to C6 when the label is at that site. Remarkably, this protecting-group role of the deuterium is unique to THF; in ether, full deprotonation of the deuterium at C3 was observed

Chemistry – A European Journal published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Quality Control of 69626-75-1.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Kraus, George A. published the artcileCoupling reactions of methoxybutenynylcopper. A facile route to substituted indoles, Safety of 2-Iodobenzofuran, the publication is Tetrahedron Letters (1978), 3195-8, database is CAplus.

Cis-MeOCH:CHCCCu with 4,2-RR¹C₆H₃I (R = NO₂, H, Me, Cl, R¹ = H; R = H, R¹ = H, NO₂; R = MeO, R¹ = NO₂) in pyridine (85-125°, 10-12 h) gave 63-94% 4,2-RR¹C₆H₃CCCH:CHOMe (I). Cis–I (R = H, R¹ = NO₂) with KOH in refluxing MeOH (4 h) gave cis– and trans-2-O₂NC₆H₄CH:C(OMe)CH₂CH(OMe)₂ which on sequential hydrolysis (aqueous MeOH, ambient temperature, yield 55%) and reduction with Al-Hg (refluxing aqueous EtOH, yield 75%) gave indole II.

Tetrahedron Letters published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Safety of 2-Iodobenzofuran.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Kuete, V. published the artcileAntimicrobial activity of the methanolic extract and compounds from Morus mesozygia stem bark, HPLC of Formula: 56317-21-6, the publication is Journal of Ethnopharmacology (2009), 124(3), 551-555, database is CAplus and MEDLINE.

Aim of the study: This study was aimed at investigating the antimicrobial activity of the methanolic extract (MMB) and compounds isolated from the stem bark of Morus mesozygia, namely 3β-acetoxyurs-12-en-11-one (1), moracin Q (2), moracin T (3), artocarpesin (4), cycloartocarpesin (5), moracin R (6), moracin U (8), moracin C (9), and moracin M (10). Materials and Methods: The liquid microdilution assay was used in the determination of the minimal inhibitory concentration (MIC) and the minimal microbicidal concentration (MMC), against nine bacterial and two fungal species. Results: The results of the MIC determination showed that the compounds 3, 4, 8 and 9 were able to prevent the growth of all tested microbial species. All other samples showed selective activities. Their inhibitory effects were noted on 90.9% studied organisms for the crude extract, 81.8% for compound 6, 72.7% for compound 10, 63.6% for compound 1, 54.5% for compound 5, and 45.5% for compound 2. The lowest MIC value of 39 μg/mL was obtained with the crude extract against Escherichia coli. The corresponding value for compounds (5 μg/mL) was registered with compound 9 on Shigella dysenteriae and compound 3 on E. coli, S. dysenteriae, Pseudomonas aeruginosa, Salmonella typhi and Bacillus cereus. The lowest MIC value (39 μg/mL) observed with the crude extract (on E. coli) was only eightfold greater than that of gentamycin used as reference antibiotic (RA) while the corresponding value (5 μg/mL) recorded with compounds 3 and 9 was equal to that of RA on the corresponding microorganisms. Conclusions: The obtained results highlighted the interesting antimicrobial potency of M. mesozygia as well as that of the studied compounds, and provided scientific basis for the traditional use of this species.

Journal of Ethnopharmacology published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, HPLC of Formula: 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Kapche, Gilbert D. W. F. published the artcilePrenylated arylbenzofuran derivatives from Morus mesozygia with antioxidant activity, HPLC of Formula: 56317-21-6, the publication is Phytochemistry (Elsevier) (2009), 70(2), 216-221, database is CAplus and MEDLINE.

Five prenylated arylbenzofurans, moracins Q-U, were isolated from Morus mesozygia (Moraceae). Their structures were elucidated on the basis of spectroscopic evidence. Along with these compounds, 3β-acetoxyurs-12-en-11-one, marsformoxide, moracin C, moracin M, moracin K, artocarpesin, cycloartocarpesin, morachalcone A were also isolated. Four of the five compounds (moracins R-U) displayed potent antioxidant activity.

Phytochemistry (Elsevier) published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, HPLC of Formula: 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Steinhuebel, Dietrich P. published the artcileStereoselective Organo-Zinc Addition Reactions to 1,2-Dihydropyrans for the Assembly of Complex Pyran Structures, SDS of cas: 69626-75-1, the publication is Organic Letters (2002), 4(2), 293-295, database is CAplus and MEDLINE.

Nucleophilic addition of organo-zinc to 1,2-dihydropyranyl acetates represents a new, broadly defined method for the stereocontrolled synthesis of α-substituted pyrans. The products obtained from this process are versatile materials that can be used to construct C-glycosides and other functionalized pyran structures of import. The occurrence of pyranyl groups in both natural products and therapeutically active agents confers added value to the studies described herein.

Organic Letters published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C18H23N3O4S, SDS of cas: 69626-75-1.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Escobedo, P. published the artcileSmart facemask for wireless CO₂ monitoring, Name: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Nature Communications (2022), 13(1), 72, database is CAplus and MEDLINE.

The use of facemasks by the general population is recommended worldwide to prevent the spread of SARS-CoV-2. Despite the evidence in favor of facemasks to reduce community transmission, there is also agreement on the potential adverse effects of their prolonged usage, mainly caused by CO2 rebreathing. Herein we report the development of a sensing platform for gaseous CO2 real-time determination inside FFP2 facemasks. The system consists of an opto-chem. sensor combined with a flexible, battery-less, near-field-enabled tag with resolution and limit of detection of 103 and 140 ppm resp., and sensor lifetime of 8 h, which is comparable with recommended FFP2 facemask usage times. We include a custom smartphone application for wireless powering, data processing, alert management, results displaying and sharing. Through performance tests during daily activity and exercise monitoring, we demonstrate its utility for non-invasive, wearable health assessment and its potential applicability for preclin. research and diagnostics.

Nature Communications published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Name: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Perez de Vargas-Sansalvador, I. M. published the artcileA new light emitting diode-light emitting diode portable carbon dioxide gas sensor based on an interchangeable membrane system for industrial applications, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Analytica Chimica Acta (2011), 699(2), 216-222, database is CAplus and MEDLINE.

A CO₂ measurement system (0-100%) based on a paired emitter-detector diode arrangement as a colorimetric detector is described. Two different configurations were tested. Configuration 1 (opposite side configuration), where a secondary inner filter effect accounted for CO₂ sensitivity, involved absorption of phosphorescence emitted from a CO₂-insensitive luminophore by an acid-base indicator. Configuration 2, where the luminophore-containing membrane was removed, simplified the sensing membrane which now only contained the acid-base indicator. Also, 2 different instrumental configurations were assessed, using a paired emitter/detector diode system consisting of 2 light-emitting diodes (LED) where one diode was used as the light source (emitter) and the other diode was used in reverse bias mode as the light detector. The first configuration used a green LED as emitter and a red LED as detector; the second configuration used 2 identical red LED as emitter and detector. The system was characterized for sensitivity, dynamic response, reproducibility, stability, and temperature influence. Results showed configuration 2 had a better CO₂ response in terms of sensitivity.

Analytica Chimica Acta published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Perez de Vargas-Sansalvador, Isabel M. published the artcileWater based-ionic liquid carbon dioxide sensor for applications in the food industry, Synthetic Route of 596-01-0, the publication is Sensors and Actuators, B: Chemical (2017), 302-309, database is CAplus.

A new water-based sensor for carbon dioxide containing an ionic liquid is presented. The sensor is based on the acidity of the CO₂ mol. The sensor incorporates an ionic liquid in the matrix, which enhances CO₂ solubility, and minimising the response and recovery times of the sensor. The entire concentration range (0-100%) of CO₂ in water has been studied. The sensor is more sensitive at low CO₂ concentrations as is usual in this kind of optical sensor. As the sensor is intended for smart food packaging, one of the most important characteristics is stability, and this has been studied under different conditions of light, temperature and relative humidity. The sensor was found to be stablef or more than 14 days, which is the period of use for the intended application. Pork chops were packed at 4 °C and the production of CO₂ studied in conjunction with total bacterial counts over a period of 14 days. The results show that the concentration of CO₂ dioxide increases in time, in correlation with bacterial counts. As the threshold of CO₂ content for human consumption of this meat is 20%, the sensor has been optimized for detection around this concentration

Sensors and Actuators, B: Chemical published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Synthetic Route of 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Escobedo, P. published the artcileFlexible Passive near Field Communication Tag for Multigas Sensing, Product Details of C28H18O4, the publication is Analytical Chemistry (Washington, DC, United States) (2017), 89(3), 1697-1703, database is CAplus and MEDLINE.

In this work we present a full-passive flexible multigas sensing tag for the determination of oxygen, carbon dioxide, ammonia, and relative humidity readable by a smart-phone. This tag is based on near field communication (NFC) technol. for energy harvesting and data transmission to a smart-phone. The gas sensors show an optic response that is read through high-resolution digital color detectors. A white LED is used as the common optical excitation source for all the sensors. Only a reduced electronics with very low power consumption is required for the reading of the optical responses and data transmission to a remote user. An application for the Android operating system has been developed for the power supplying and data reception from the tag. The responses of the sensors have been calibrated and fitted to simple functions, allowing a fast prediction of the gases concentration Cross-sensitivity has also been evaluated, finding that in most of the cases it is negligible or easily correctable using the rest of the readings. The election of the target gases has been due to their importance in the monitoring of modified atm. packaging. The resolutions and limits of detection measured are suitable for such kinds of applications.

Analytical Chemistry (Washington, DC, United States) published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Product Details of C28H18O4.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem