Li, Hong Xu’s team published research in Molecules in 23 | CAS: 56317-21-6

Molecules published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Formula: C14H10O4.

Li, Hong Xu published the artcileIdentification of anti-melanogenesis constituents from morus alba l. leaves, Formula: C14H10O4, the publication is Molecules (2018), 23(10), 1-11, database is CAplus and MEDLINE.

The individual parts of Morus alba L. including root bark, branches, leaves, and fruits are used as a cosmetic ingredient in many Asian countries. This study identified several anti-melanogenesis constituents in a 70% ethanol extract of M. alba leaves. The Et acetate fraction of the initial ethanol extract decreased the activity of tyrosinase, a key enzyme in the synthetic pathway of melanin. Twelve compounds were isolated from this fraction and their structures were identified based on spectroscopic spectra. Then, the authors investigated the anti-melanogenesis effects of the isolated compounds in B16-F10 mouse melanoma cells. Compounds 3 and 8 significantly inhibited not only melanin production but also intracellular tyrosinase activity in alpha-melanocyte-stimulating-hormone (a-MSH)-induced B16-F10 cells in a dose-dependent manner. These same compounds also inhibited melanogenesis-related protein expression such as microphthalmia-associated transcription factor (MITF), tyrosinase, and tyrosinase-related protein-1 (TRP-1). Compound 3 modulated the cAMP-responsive element-binding protein (CREB) and p38 signaling pathways in a-MSH-activated B16-F10 melanoma cells, which resulted in the anti-melanogenesis effects. These results suggest that compound 3, isolated from M. alba leaves, could be used to inhibit melanin production via the regulation of melanogenesis-related protein expression.

Molecules published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Formula: C14H10O4.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Riviere, Celine’s team published research in Bioorganic & Medicinal Chemistry Letters in 20 | CAS: 56317-21-6

Bioorganic & Medicinal Chemistry Letters published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Safety of 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Riviere, Celine published the artcileNew stilbene dimers against amyloid fibril formation, Safety of 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, the publication is Bioorganic & Medicinal Chemistry Letters (2010), 20(11), 3441-3443, database is CAplus and MEDLINE.

Twenty stilbene derivatives and moracin M extracted from natural products were tested against amyloid-β peptide (Aβ) aggregation. Results of stilbene monomer derivatives indicated that interaction with resveratrol and piceid was specific. Concerning oligomers, scirpusin A and ε-viniferin glucoside demonstrated a strong inhibition of the aggregation process.

Bioorganic & Medicinal Chemistry Letters published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Safety of 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Hashmi, A. Stephen K.’s team published research in Advanced Synthesis & Catalysis in 351 | CAS: 69626-75-1

Advanced Synthesis & Catalysis published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Name: 2-Iodobenzofuran.

Hashmi, A. Stephen K. published the artcileGold Catalysis: Anellated Heterocycles and Dependency of the Reaction Pathway on the Tether Length, Name: 2-Iodobenzofuran, the publication is Advanced Synthesis & Catalysis (2009), 351(17), 2855-2875, database is CAplus.

A series of furan-yne substrates with an arylalkynylamide substructure were prepared and subjected to catalytic amounts of phosphanegold(I) complexes. With two carbon atoms in the tether between the arylalkynylamide and the furan subunits, the formation of benzoanellated heterocycles was observed, and a number of interesting fused dihydroindole frameworks, e.g., I, could be accessed in this way. With three carbon atoms in the tether, the outcome was quite different, cyclopentadiene derivatives anellated to tetrahydropyridine rings, e.g., II, were isolated. The two different pathways suggested are supported by calculations regarding the selectivity-determining step.

Advanced Synthesis & Catalysis published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Name: 2-Iodobenzofuran.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Sorensen, S. P. L.’s team published research in Biochemische Zeitschrift in 24 | CAS: 596-01-0

Biochemische Zeitschrift published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C15H14N2, Name: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Sorensen, S. P. L. published the artcileA New Indicator, α-Naphtholphthalein, with Color Change near the Neutral Point, Name: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Biochemische Zeitschrift (1910), 381-6, database is CAplus.

The substance is made by the method of Grabowski (Ber., 4, 725). It shows a good color change at an H ion concentrate of 10-7.26 to 10-8.68. Proteins interfere with the end reaction.

Biochemische Zeitschrift published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C15H14N2, Name: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Chakrabarty, Suman’s team published research in Chemical Science in 10 | CAS: 69626-75-1

Chemical Science published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, COA of Formula: C8H5IO.

Chakrabarty, Suman published the artcileFacile access to functionalized chiral secondary benzylic boronic esters via catalytic asymmetric hydroboration, COA of Formula: C8H5IO, the publication is Chemical Science (2019), 10(18), 4854-4861, database is CAplus and MEDLINE.

Allylic and homoallylic phosphonates bearing an aryl or heteroaryl substituent at the γ- or δ-position undergo rhodium-catalyzed asym. hydroboration by pinacolborane to give functionalized chiral secondary benzylic boronic esters in yields up to 86% and enantiomer ratios up to 99 : 1. Compared to minimally-functionalized terminal and 1,1-disubstituted vinyl arenes, there are relatively few reports of efficient catalytic asym. hydroboration (CAHB) of more highly functionalized internal alkenes. Phosphonate substrates bearing a variety of common heterocyclic ring systems, including furan, indole, pyrrole and thiophene derivatives, as well as those bearing basic nitrogen substituents (e.g., morpholine and pyrazine) are tolerated, although donor substituents positioned in close proximity of the alkene can influence the course of the reaction. Stereoisomeric (E)- and (Z)-substrates afford the same major enantiomer of the borated product. Deuterium-labeling studies reveal that rapid (Z)- to (E)-alkene isomerization accounts for the observed (E/Z)-stereoconvergence during CAHB. The synthetic utility of the chiral boronic ester products is illustrated by stereospecific C-B bond transformations including stereoretentive electrophile promoted 1,2-B-to-C migrations, stereoinvertive SE2 reactions of boron-ate complexes with electrophiles, and stereoretentive palladium- and rhodium-catalyzed cross-coupling protocols.

Chemical Science published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, COA of Formula: C8H5IO.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Matsuki, Yuki’s team published research in Nature Communications in 12 | CAS: 69626-75-1

Nature Communications published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Related Products of benzofurans.

Matsuki, Yuki published the artcileAryl radical-mediated N-heterocyclic carbene catalysis, Related Products of benzofurans, the publication is Nature Communications (2021), 12(1), 3848, database is CAplus and MEDLINE.

There have been significant advancements in radical reactions using organocatalysts in modern organic synthesis. Recently, NHC-catalyzed radical reactions initiated by single electron transfer processes have been actively studied. However, the reported examples have been limited to catalysis mediated by alkyl radicals. In this article, the NHC organocatalysis mediated by aryl radicals has been achieved. The enolate form of the Breslow intermediate derived from an aldehyde and thiazolium-type NHC in the presence of a base undergoes single electron transfer to an aryl iodide, providing an aryl radical. The catalytically generated aryl radical could be exploited as an arylating reagent for radical relay-type arylacylation of styrenes and as a hydrogen atom abstraction reagent for α-amino C(sp3)-H acylation of secondary amides.

Nature Communications published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Related Products of benzofurans.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Korenman, Ya. I.’s team published research in Journal of Analytical Chemistry (Translation of Zhurnal Analiticheskoi Khimii) in 53 | CAS: 596-01-0

Journal of Analytical Chemistry (Translation of Zhurnal Analiticheskoi Khimii) published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Application In Synthesis of 596-01-0.

Korenman, Ya. I. published the artcileTitrimetric determination of aromatic acids in nonaqueous concentrates, Application In Synthesis of 596-01-0, the publication is Journal of Analytical Chemistry (Translation of Zhurnal Analiticheskoi Khimii) (1998), 53(12), 1125-1130, database is CAplus.

The extraction of aromatic acids by hydrophilic solvents from aqueous solutions in the absence and the presence of salts was studied. Efficient extraction systems are proposed as media for nonaqueous titrations Procedures for the sep. titrimetric, potentiometric, conductometric, and photometric determination of aromatic acids in nonaqueous concentrates were developed.

Journal of Analytical Chemistry (Translation of Zhurnal Analiticheskoi Khimii) published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Application In Synthesis of 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Hedvall, J. A.’s team published research in Arkiv foer Kemi, Mineralogi och Geologi in 17A | CAS: 596-01-0

Arkiv foer Kemi, Mineralogi och Geologi published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Hedvall, J. A. published the artcilePhotoadsorption effects in the system pigment-fluid phase, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Arkiv foer Kemi, Mineralogi och Geologi (1943), 17A(No. 11), 11 pp., database is CAplus.

The adsorption by red and black HgS of phenolphthalein from aqueous EtOH solution and by CdS of α-naphtholphthalein from similar solutions has been investigated under varying light conditions. Light has little effect on adsorption by black HgS but red HgS adsorbs six times as much phthalein in light as in darkness. This difference is ascribed to the different electronic structures of red and black HgS. Black HgS and irradiated red HgS are conductors, whereas in darkness red HgS is an insulator. CdS adsorbs phthalein much more when irradiated than in darkness. In each case adsorption in darkness is increased by presence of excess of S in the sulfide, A parallel is drawn between these photoadsorption effects and the Becquerel or photovoltaic effect.

Arkiv foer Kemi, Mineralogi och Geologi published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Tran, Huynh Nguyen Khanh’s team published research in Fitoterapia in 120 | CAS: 56317-21-6

Fitoterapia published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C5H9IO2, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Tran, Huynh Nguyen Khanh published the artcileAnti-inflammatory activities of compounds from twigs of Morus alba, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, the publication is Fitoterapia (2017), 17-24, database is CAplus and MEDLINE.

Five new compounds, 10-oxomornigrol F (1), (7′′R)-(-)-6-(7′′-hydroxy-3′′,8′′-dimethyl-2′′,8′′-octadien-1′′-yl)apigenin (2), ramumorin A (3), ramumorin B (4), and (4S,7S,8R)-trihydroxyoctadeca-5Z-enoic acid (5), together with 31 known compounds (6-36), were isolated from the twigs of Morus alba (Moraceae). The chem. structures of these compounds were established using spectroscopic analyses, 1D and 2D NMR, high-resolution electrospray ionization mass spectrometry (HRESIMS), and Mosher′s methods. The anti-inflammatory activities of the compounds were evaluated by investigating their ability to inhibit lipopolysaccharide (LPS)-induced nitric oxide (NO) production in macrophage RAW 264.7 cells. Compounds 1, 2, 13, 17, 19, 25-28, and 32 showed inhibitory effects with IC50 values ranging from 2.2 to 5.3 μg/mL. Compounds 1, 2, 17, 25, and 32 reduced LPS-induced inducible nitric oxide synthase (iNOS) expression in a concentration-dependent manner. In addition, pretreating the cells with compound 1, 17, and 32 significantly suppressed LPS-induced expression of cyclooxygenase-2 (COX-2) protein.

Fitoterapia published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C5H9IO2, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Garcia-Dominguez, Patricia’s team published research in Journal of the American Chemical Society in 138 | CAS: 69626-75-1

Journal of the American Chemical Society published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Product Details of C8H5IO.

Garcia-Dominguez, Patricia published the artcileAu-Pd Bimetallic Catalysis: The Importance of Anionic Ligands in Catalyst Speciation, Product Details of C8H5IO, the publication is Journal of the American Chemical Society (2016), 138(10), 3266-3269, database is CAplus and MEDLINE.

Synergistic gold-palladium catalytic processes have been intensively sought during the past decade, because the combination of the carbophilic Lewis acidity of Au with the redox properties of Pd within a catalytic cycle particularly appealing for the synthesis of novel functionalized compounds We demonstrate here the feasibility of a Au-Pd bimetallic catalytic system based on the generation of competent Au and Pd species by anionic ligand exchange. This strategy enabled the preparation of a variety of substituted butenolides in a simple and efficient way.

Journal of the American Chemical Society published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Product Details of C8H5IO.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem