Day: November 25, 2022

He, Jiahong published the artcileInsight into the corrosion inhibition property of Artocarpus heterophyllus Lam leaves extract, Computed Properties of 56317-21-6, the publication is Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) (2021), 260-270, database is CAplus.

In this work, the method (water extraction way) was uesd to acquire Artocarpus heterophyllus Lam leaves extract (AHLLE). We refer to the relevant references on the composition of Artocarpus heterophyllus Lam leaves and perform Fourier IR spectroscopy anal. for AHLLE. It can be concluded that AHLLE contains 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one (DPD), (2R,3R)-2-(2,4-dihydroxyphenyl)-3 ,5,7-trihydroxychroman-4-one (DPT), 3-(4-hydroxyphenyl)acrylic acid (HPT), and 5-(6-hydroxybenzofuran-2-yl)benzene-1,3-diol (HBB). Quantum chem. calculations (QCC) data and mol. dynamics (MD) simulations results show that DPD, DPT, HPT, and HBB all have the potential of excellent corrosion inhibitors. Scanning electron microscope (SEM) results and at. force microscope (AFM) test results show that after adding AHLLE to H2SO4 environment, the copper surface is still correspondingly flat. In addition, the results of electrochem. experiments indicate that the AHLLE is 500 ppm, the anti-corrosion efficiency obtained from electrochem. impedance spectroscopy data can reach 97.3%. With the temperature augments to 313 K, the corrosion inhibition nature of AHLLE can still be maintained to 97%. AHLLE is adsorbed onto the Cu surface and belongs to Langmuir monolayer adsorption.

Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Computed Properties of 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Wang, Ping published the artcilePhenylpropanoids and diphenylethene compounds from roots and rhizomes of Smilax scobinicaulis, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, the publication is Zhongguo Zhongyao Zazhi (2013), 38(10), 1531-1535, database is CAplus and MEDLINE.

The chem. constituents were separated and purified from the roots and rhizomes of Smilax scobinicaulis by various chromatog. methods including silica gel, Sephadex LH-20. Their structures were obtained and identified as resveratrol-3-O-β-D-glucopyranosyl-(1->3)-β-D-glucopyranoside(1), resveratrol(2), δ-viniferin(3), Et caffeate(4), 1-O-caffeoyl glycerol(5), 1-O-p-coumaroyl glycerol(6), 1-O-feruloyl glycerol(7), grossamide(8), moracin M(9) on the anal. of spectroscopic data. Compound 1 was a new compound and compounds 3-5, 8, 9 were separated from this plant for the first time.

Zhongguo Zhongyao Zazhi published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C9H8O4, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Negishi, Ei-ichi published the artcileDirect synthesis of heteroarylethynes via palladium-catalyzed coupling of heteroaryl halides with ethynylzinc halides. Its application to an efficient synthesis of a thiophenelactone from Chamaemelum nobile L, Computed Properties of 69626-75-1, the publication is Heterocycles (1997), 209-214, database is CAplus.

A variety of terminal alkynes containing a heteroaryl group can be directly and selectively synthesized by the Pd-catalyzed coupling of heteroaryl iodides or bromides with ethynylzinc halides. Various compounds of this class containing furan, thiophene, and pyridine have been prepared, and the procedure has been applied to an efficient and selective synthesis of a thiophenelactone from Chamaemelum nobile L.

Heterocycles published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Computed Properties of 69626-75-1.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Zhang, Fuyi published the artcileGeneral and efficient one-pot synthesis of novel sugar/heterocyclic(aryl) 1,2-diketones from sugar terminal alkynes by Sonogashira/tetra-n-butylammonium permanganate oxidation, HPLC of Formula: 69626-75-1, the publication is Carbohydrate Research (2015), 41-51, database is CAplus and MEDLINE.

A new approach for one-pot synthesis of novel sugar/heterocyclic(aryl) 1,2-diketones has been achieved by the reaction of various sugar terminal alkynes with heterocyclic(aryl) iodides at room temperature This one-pot protocol includes Sonogashira coupling and mild n-Bu₄NMnO₄ oxidation reaction. This method is mild, general and efficient. Fifty-six examples have been given and the sugar/heterocyclic(aryl) 1,2-diketones were obtained in 71-94% yields. The sugar terminal alkynes include 9 structurally different sugars in pyranose, furanose, and acyclic form which have various protecting groups, sensitive groups, and sterically bulky substituents. The heterocyclic(aryl) iodides include sterically bulky heterocyclic compounds and iodobenzenes with electron-donating, electron-neutral, and electron-withdrawing substituents.

Carbohydrate Research published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C10H16Br3N, HPLC of Formula: 69626-75-1.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Wu, Kai published the artcileTransition-Metal-Free C(sp²)-C(sp²) Cross-Coupling of Diazo Quinones with Catechol Boronic Esters, Name: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, the publication is Angewandte Chemie, International Edition (2020), 59(37), 16202-16208, database is CAplus and MEDLINE.

A transition-metal-free C(sp²)-C(sp²) bond formation reaction by the cross-coupling of diazo quinones with catechol boronic esters was developed. With this protocol, a variety of biaryls and alkenyl phenols were obtained in good to high yields under mild conditions [e.g., ortho-diazo quinone I + catechol boronic ester II → III (94%) using K₂CO₃ as base and MeCN/DCM mixed solvent]. The reaction tolerates various functionalities and is applicable to the derivatization of pharmaceuticals and natural products. The synthetic utility of the method was demonstrated by the short synthesis of multi-substituted triphenylenes and three bioactive natural products, honokiol, moracin M, and stemofuran A. Mechanistic studies and d. functional theory (DFT) calculations revealed that the reaction involves attack of the boronic ester by a singlet quinone carbene followed by a 1,2-rearrangement through a stepwise mechanism. Safety: diazo quinones are potentially explosive.

Angewandte Chemie, International Edition published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C7H8FNO2S, Name: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

He, Xue-mei published the artcileChemical constituents from the root bark of Morus atropurpurea, Computed Properties of 56317-21-6, the publication is Xiandai Shipin Keji (2014), 30(6), 219-228, 300, database is CAplus.

Mulberry root bark (Sang Bai Pi) was a kind of traditional Chinese medicine which showed hypotensive, antiviral bacteriostatic and anti-inflammatory activities. In order to explore the material basis of pharmacol. activity of mulberry root bark, the chem. constituents of the root bark from Moms atropurpurea was studied in this paper. Fifteen compounds were isolated from the root bark by silica gel, Sephadex LH-20, ODS and PHPLC column chromatog. Their structures were identified by physicochem. properties and spectral anal. as kuwanon A (1), kuwanon B (2), kuwanon C (3), kuwanon T (4), cyclomorusin (5), moracin M (6), moracin O (7), moracin P (8), mulberrofuran L (9), albanin A (10), australone A (11), 5′-(1”’,1”’-dimethylallyl)-8-(3″,3″-dimethylallyl)-2′,4′,5,7-tetrahydroxyfla-vone (12), 5,7-dihydroxycoumarin (13), oxyresceratrol (14) and β-daucosterol (15), resp. Fifteen compounds contained eight prenylflavonoids, four 2-arylbenzofuran, one coumarin, one stilbene and one sterol. Moreover, compounds 1-4 and 7-13 were firstly found from Moms atropurpurea.

Xiandai Shipin Keji published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Computed Properties of 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Wen, Chang published the artcileHighly Efficient Synthesis of 2-Substituted Benzo[ b ]furan Derivatives from the Cross-Coupling Reactions of 2-Halobenzo[ b ]furans with Organoalane Reagents, COA of Formula: C8H5IO, the publication is Synthesis (2021), 53(20), 3847-3861, database is CAplus.

A highly efficient and simple route for the synthesis of benzo[ b]furans was developed by palladium-catalyzed cross-coupling reaction of 2-halobenzo[ b]furans with aryl, alkynyl, and alkylaluminum reagents. Various 2-aryl-, 2-alkynyl-, and 2-alkyl benzo[ b]furans was obtained in 23-97% isolated yields using 2-3 mol% PdCl 2/4-6 mol% XantPhos as the catalyst under mild reaction conditions. The aryls beared electron-donating or electron-withdrawing groups in 2-halobenzo[ b]furans gave products in 40-97% isolated yields. In addition, aluminum reagents containing thienyl, furanyl, trimethylsilanyl, and benzyl groups worked efficiently with 2-halobenzo[ b]furans as well, and three bioactive mols. with benzo[ b]furans skeleton were synthesized. Furthermore, the broad substrates scope and the typical maintenance of vigorous efficiency on gram scale made this protocol a potentially practical method to synthesize benzo[ b]furans. On the basis of the exptl. results, a possible catalytic cycle was proposed.

Synthesis published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C22H32O2, COA of Formula: C8H5IO.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Mann, Inderjit S. published the artcileTransition metal-directed synthesis of moracin M, a phytoalexin of Morus alba Linn, Safety of 2-Iodobenzofuran, the publication is Tetrahedron (1991), 47(37), 7981-90, database is CAplus.

2-(5-Resorcinyl)benzofurans have been synthesized by the Pd-catalyzed cross-coupling of 2-trimethylstannyl- or 2-bromozincbenzofurans with functionalized 5-iodoresorcinols. These were synthesized by the triisopropylsilyloxy-directed remote (C-5) lithiation/iodination of the O,O-bis(triisopropylsilyl)resorcinoltricarbonylchrhomium(0) complex. The method was applied to the synthesis of moracin M (I).

Tetrahedron published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Safety of 2-Iodobenzofuran.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Czyz, M. L. published the artcileA visible-light photocatalytic thiolation of aryl, heteroaryl and vinyl iodides, Category: benzofurans, the publication is Organic & Biomolecular Chemistry (2018), 16(9), 1543-1551, database is CAplus and MEDLINE.

The general catalytic synthesis of aryl and vinyl thioethers from readily available halides remains a challenge. Herein we report a unified method for the thiolation of aryl and vinyl iodides with dialkyl disulfides using visible light photoredox catalysis. A range of thioether products bearing diverse functional groups can be accessed in high yield and with excellent chemoselectivity. We demonstrate the versatility of this method through the expedient synthesis of a family of thioether-rich natural products. A detailed investigation of the photocatalytic mechanism is presented from both steady-state and time-resolved luminescent quenching as well as transient absorption spectroscopy experiments

Organic & Biomolecular Chemistry published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Category: benzofurans.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Liu, Huitao published the artcileQuantitative structure-property relationship study on the determination of binding constant by fluorescence quenching, Application In Synthesis of 596-01-0, the publication is Central European Journal of Chemistry (2009), 7(1), 59-65, database is CAplus.

Models to predict binding constant (logK) to bovine serum albumin (BSA) should be very useful in the pharmaceutical industry to help speed up the design of new compounds, especially as far as pharmacokinetics is concerned. We present here an extensive list of logK binding constants for thirty-five compounds to BSA determined by florescence quenching from the literature. These data have allowed us the derivation of a quant. structure-property relationship (QSPR) model to predict binding constants to BSA of compounds on the basis of their structure. A stepwise multiple linear regression (MLR) was performed to build the model. The statistical parameter provided by the MLR model (R = 0.9200, RMS = 0.3305) indicated satisfactory stability and predictive ability for the model. Using florescence quenching spectroscopy, we also exptl. determined the binding constants to BSA for two bioactive components in traditional Chinese medicines. Using the proposed model it was possible to predict the binding constants for each, which were in good agreement with the exptl. results. This QSPR approach can contribute to a better understanding of structural factors of the compounds responsible for drug-protein interactions, and be useful in predicting the binding constants of other compounds

Central European Journal of Chemistry published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Application In Synthesis of 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem