He, Jiahong’s team published research in Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) in 102 | CAS: 56317-21-6

Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Computed Properties of 56317-21-6.

He, Jiahong published the artcileInsight into the corrosion inhibition property of Artocarpus heterophyllus Lam leaves extract, Computed Properties of 56317-21-6, the publication is Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) (2021), 260-270, database is CAplus.

In this work, the method (water extraction way) was uesd to acquire Artocarpus heterophyllus Lam leaves extract (AHLLE). We refer to the relevant references on the composition of Artocarpus heterophyllus Lam leaves and perform Fourier IR spectroscopy anal. for AHLLE. It can be concluded that AHLLE contains 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one (DPD), (2R,3R)-2-(2,4-dihydroxyphenyl)-3 ,5,7-trihydroxychroman-4-one (DPT), 3-(4-hydroxyphenyl)acrylic acid (HPT), and 5-(6-hydroxybenzofuran-2-yl)benzene-1,3-diol (HBB). Quantum chem. calculations (QCC) data and mol. dynamics (MD) simulations results show that DPD, DPT, HPT, and HBB all have the potential of excellent corrosion inhibitors. Scanning electron microscope (SEM) results and at. force microscope (AFM) test results show that after adding AHLLE to H2SO4 environment, the copper surface is still correspondingly flat. In addition, the results of electrochem. experiments indicate that the AHLLE is 500 ppm, the anti-corrosion efficiency obtained from electrochem. impedance spectroscopy data can reach 97.3%. With the temperature augments to 313 K, the corrosion inhibition nature of AHLLE can still be maintained to 97%. AHLLE is adsorbed onto the Cu surface and belongs to Langmuir monolayer adsorption.

Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Computed Properties of 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Wang, Ping’s team published research in Zhongguo Zhongyao Zazhi in 38 | CAS: 56317-21-6

Zhongguo Zhongyao Zazhi published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C9H8O4, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Wang, Ping published the artcilePhenylpropanoids and diphenylethene compounds from roots and rhizomes of Smilax scobinicaulis, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, the publication is Zhongguo Zhongyao Zazhi (2013), 38(10), 1531-1535, database is CAplus and MEDLINE.

The chem. constituents were separated and purified from the roots and rhizomes of Smilax scobinicaulis by various chromatog. methods including silica gel, Sephadex LH-20. Their structures were obtained and identified as resveratrol-3-O-β-D-glucopyranosyl-(1->3)-β-D-glucopyranoside(1), resveratrol(2), δ-viniferin(3), Et caffeate(4), 1-O-caffeoyl glycerol(5), 1-O-p-coumaroyl glycerol(6), 1-O-feruloyl glycerol(7), grossamide(8), moracin M(9) on the anal. of spectroscopic data. Compound 1 was a new compound and compounds 3-5, 8, 9 were separated from this plant for the first time.

Zhongguo Zhongyao Zazhi published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C9H8O4, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Wu, Kai’s team published research in Angewandte Chemie, International Edition in 59 | CAS: 56317-21-6

Angewandte Chemie, International Edition published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C7H8FNO2S, Name: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Wu, Kai published the artcileTransition-Metal-Free C(sp2)-C(sp2) Cross-Coupling of Diazo Quinones with Catechol Boronic Esters, Name: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, the publication is Angewandte Chemie, International Edition (2020), 59(37), 16202-16208, database is CAplus and MEDLINE.

A transition-metal-free C(sp2)-C(sp2) bond formation reaction by the cross-coupling of diazo quinones with catechol boronic esters was developed. With this protocol, a variety of biaryls and alkenyl phenols were obtained in good to high yields under mild conditions [e.g., ortho-diazo quinone I + catechol boronic ester IIIII (94%) using K2CO3 as base and MeCN/DCM mixed solvent]. The reaction tolerates various functionalities and is applicable to the derivatization of pharmaceuticals and natural products. The synthetic utility of the method was demonstrated by the short synthesis of multi-substituted triphenylenes and three bioactive natural products, honokiol, moracin M, and stemofuran A. Mechanistic studies and d. functional theory (DFT) calculations revealed that the reaction involves attack of the boronic ester by a singlet quinone carbene followed by a 1,2-rearrangement through a stepwise mechanism. Safety: diazo quinones are potentially explosive.

Angewandte Chemie, International Edition published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C7H8FNO2S, Name: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

He, Xue-mei’s team published research in Xiandai Shipin Keji in 30 | CAS: 56317-21-6

Xiandai Shipin Keji published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Computed Properties of 56317-21-6.

He, Xue-mei published the artcileChemical constituents from the root bark of Morus atropurpurea, Computed Properties of 56317-21-6, the publication is Xiandai Shipin Keji (2014), 30(6), 219-228, 300, database is CAplus.

Mulberry root bark (Sang Bai Pi) was a kind of traditional Chinese medicine which showed hypotensive, antiviral bacteriostatic and anti-inflammatory activities. In order to explore the material basis of pharmacol. activity of mulberry root bark, the chem. constituents of the root bark from Moms atropurpurea was studied in this paper. Fifteen compounds were isolated from the root bark by silica gel, Sephadex LH-20, ODS and PHPLC column chromatog. Their structures were identified by physicochem. properties and spectral anal. as kuwanon A (1), kuwanon B (2), kuwanon C (3), kuwanon T (4), cyclomorusin (5), moracin M (6), moracin O (7), moracin P (8), mulberrofuran L (9), albanin A (10), australone A (11), 5′-(1”’,1”’-dimethylallyl)-8-(3″,3″-dimethylallyl)-2′,4′,5,7-tetrahydroxyfla-vone (12), 5,7-dihydroxycoumarin (13), oxyresceratrol (14) and β-daucosterol (15), resp. Fifteen compounds contained eight prenylflavonoids, four 2-arylbenzofuran, one coumarin, one stilbene and one sterol. Moreover, compounds 1-4 and 7-13 were firstly found from Moms atropurpurea.

Xiandai Shipin Keji published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Computed Properties of 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Wang, Zhiren’s team published research in Journal of Medicinal Chemistry in 58 | CAS: 56317-21-6

Journal of Medicinal Chemistry published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C16H12O, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Wang, Zhiren published the artcileDesign, Synthesis, and Evaluation of Orally Available Clioquinol-Moracin M Hybrids as Multitarget-Directed Ligands for Cognitive Improvement in a Rat Model of Neurodegeneration in Alzheimer’s Disease, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, the publication is Journal of Medicinal Chemistry (2015), 58(21), 8616-8637, database is CAplus and MEDLINE.

A novel series of clioquinol-moracin hybrids were designed and synthesized by fusing the pharmacophores of clioquinol and moracin M, and their activities as multitarget-directed ligands against Alzheimer’s disease were evaluated. Biol. activity results demonstrated that these hybrids possessed significant inhibitory activities against phosphodiesterase 4D (PDE4D) and Aβ aggregation as well as remarkable antioxidant effects and excellent blood-brain barrier permeability. The optimal compound, I (WBQ5187), exhibited excellent PDE4D inhibitory potency (IC50 = 0.32 μM), significant antioxidant effects, appropriate biometal chelating functions, and interesting properties that modulated self- and metal-induced Aβ aggregation. Two-dimensional NMR studies revealed that I had significant interactions with Aβ1-42 at the R5, H6, H14, Q15, and F20 residues. Furthermore, this typical hybrid possessed preeminent neuroprotective effects against inflammation in microglial cells. Most importantly, oral administration of I·HCl demonstrated marked improvements in cognitive and spatial memory in a rat model of Alzheimer’s disease and protected hippocampal neurons from necrosis.

Journal of Medicinal Chemistry published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C16H12O, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Li, Ruilin’s team published research in Phytomedicine in 92 | CAS: 56317-21-6

Phytomedicine published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Li, Ruilin published the artcileA combined network pharmacology and molecular biology approach to investigate the active ingredients and potential mechanisms of mulberry (Morus alba L.) leaf on obesity, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, the publication is Phytomedicine (2021), 153714, database is CAplus and MEDLINE.

As one of traditional Chinese medicine, mulberry leaf is abundant in diverse active ingredients and widely used for the treatment of metabolic disease and its complications. However, there are a few of reports on its application in the prevention and treatment of obesity. And the mol. mechanism on the anti-obesity of mulberry leaf are unknown till now. The present study aimed to evaluate the potential ingredients and targets of mulberry leaf and uncover the anti-obesity mechanisms by using the network pharmacol. tactics and verify its effect by biol. experiments Active ingredients and key targets of mulberry leaf, genes related to obesity were screened through public database. Based on the results of network pharmacol., the flavonoids-enriched fraction of mulberry leaf (MLF) was extracted and composition of this fraction was identified. After that, HepG2 cells model of lipid accumulation was established for verifying the effect of MLF and related mechanisms. A total of 37 active ingredients in mulberry leaf, 192 predicted biol. targets and 8813 obesity-related targets were determined, of which 180 overlapping targets might have obvious curative effects on obesity. The networks showed that mulberry leaf might play a role through key targets, such as AKT, MAPK and IL-6, and regulated PI3K-Akt signaling pathway. Based on HPLC-ESI-QQQ-MS anal., 13 constituents of MLF were identified, including 9 flavonoids. Furthermore, HepG2 cells model of lipid accumulation was established. The results indicated that MLF treatment could down-regulate the secretion of inflammatory cytokines, as well as clearly inhibited lipid droplets formation and alleviated TC, TG, HDL-C and LDL-C levels. Pos. effect was observed on hypolipidemic efficacy due to the regulation of PI3K/Akt/Bcl-xl pathway, as indicated by the amelioration of PI3K, Akt and Bcl-xl gene and protein expression. This study firstly systematically disclose the multi-ingredients, multi-targets mechanisms of mulberry leaf on obesity by using network pharmacol. approach, and validate in HepG2 cells that the protective effect of MLF against obesity involved both inflammation response and lipid metabolism involving PI3K/Akt/Bcl-xl signaling pathway. It provides indications for further mechanistic research of mulberry leaf and also for the development as a potential candidate for the therapy for obese patients.

Phytomedicine published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Pflieger, Aude’s team published research in PLoS One in 8 | CAS: 56317-21-6

PLoS One published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, SDS of cas: 56317-21-6.

Pflieger, Aude published the artcileNatural stilbenoids isolated from grapevine exhibiting inhibitory effects against HIV-1 integrase and eukaryote MOS1 transposase in vitro activities, SDS of cas: 56317-21-6, the publication is PLoS One (2013), 8(11), e81184/1-e81184/13, 13 pp., database is CAplus and MEDLINE.

Polynucleotidyl transferases are enzymes involved in several DNA mobility mechanisms in prokaryotes and eukaryotes. Some of them such as retroviral integrases are crucial for pathogenous processes and are therefore good candidates for therapeutic approaches. To identify new therapeutic compounds and new tools for investigating the common functional features of these proteins, we addressed the inhibition properties of natural stilbenoids deriving from resveratrol on two models: the HIV-1 integrase and the eukaryote MOS-1 transposase. Two resveratrol dimers, leachianol F and G, were isolated for the first time in Vitis along with fourteen known stilbenoids: E-resveratrol, E-piceid, E-pterostilbene, E-piceatannol, (+)- E-ε-viniferin, E-ε-viniferinglucoside, E-scirpusin A, quadragularin A, ampelopsin A, pallidol, E-miyabenol C, E-vitisin B, hopeaphenol, and isohopeaphenol and were purified from stalks of Vitis vinifera (Vitaceae), and moracin M from stem bark of Milliciaexelsa (Moraceae). These compounds were tested in in vitro and in vivo assays reproducing the activity of both enzymes. Several mols. presented significant inhibition on both systems. Some of the mols. were found to be active against both proteins while others were specific for one of the two models. Comparison of the differential effects of the mols. suggested that the compounds could target specific intermediate nucleocomplexes of the reactions. Addnl. E-pterostilbene was found active on the early lentiviral replication steps in lentiviruses transduced cells. Consequently, in addition to representing new original lead compounds for further modeling of new active agents against HIV-1 integrase, these mols. could be good tools for identifying such reaction intermediates in DNA mobility processes.

PLoS One published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, SDS of cas: 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Ma, Fang’s team published research in Biological & Pharmaceutical Bulletin in 39 | CAS: 56317-21-6

Biological & Pharmaceutical Bulletin published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Quality Control of 56317-21-6.

Ma, Fang published the artcileAnti-HSV activity of Kuwanon X from Mulberry leaves with genes expression inhibitory and HSV-1 induced NF-κB deactivated properties, Quality Control of 56317-21-6, the publication is Biological & Pharmaceutical Bulletin (2016), 39(10), 1667-1674, database is CAplus and MEDLINE.

Six stilbene derivatives isolated from Mulberry leaves including Kuwanon X, Mulberrofuran C, Mulberrofuran G, Moracin C, Moracin M 3′-O-b-glucopyranoside and Moracin M were found to have antiviral effects against herpes simplex virus type 1 and 2 (HSV-1 and HSV-2) at different potencies except for Mulberrofuran G. Kuwanon X exhibited the greatest activity against HSV-1 15577 and clin. strains and HSV-2 strain 333 with IC50 values of 2.2, 1.5 and 2.5μg/mL, resp. Further study revealed that Kuwanon X did not inactivate cell-free HSV-1 particles, but inhibited cellular adsorption and penetration of HSV-1 viral particles. Following viral penetration, Kuwanon X reduced the expression of HSV-1 IE and L genes, and decreased the synthesis of HSV-1 DNA. Furthermore, it was demonstrated that Kuwanon X inhibited the HSV-1-induced nuclear factor (NF)-κB activation through blocking the nuclear translocation and DNA binding of NF-κB. These results suggest that Kuwanon X exerts anti-HSV activity through multiple modes and could be a potential candidate for the therapy of HSV infection.

Biological & Pharmaceutical Bulletin published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Quality Control of 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Zhou, Siqi’s team published research in Food & Function in 11 | CAS: 56317-21-6

Food & Function published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C7H3Cl2F3O2S, Product Details of C14H10O4.

Zhou, Siqi published the artcileA chondroprotective effect of moracin on IL-1β-induced primary rat chondrocytes and an osteoarthritis rat model through Nrf2/HO-1 and NF-κB axes, Product Details of C14H10O4, the publication is Food & Function (2020), 11(9), 7935-7945, database is CAplus and MEDLINE.

Osteoarthritis (OA) is a common joint disease characterized by cartilage degeneration and inflammation. Although moracin is known to play a role in anti-inflammation and anti-oxidation in several inflammatory diseases, its anti-inflammatory effect on OA remains largely unknown. Therefore, in order to explore the role of moracin in OA, we investigated the anti-inflammatory effect of moracin on interleukin (IL)-β-induced rat chondrocytes in vitro and surgically induced OA rat models in vivo. Rat chondrocytes were pretreated using moracin (0, 5, 10, 15μmol L-1) and then stimulated with IL-β (10 ng ml-1). Results showed that moracin reduced the expression of IL-1β-induced nitric oxide (NO), prostaglandin E2 (PGE2), tumor necrosis factor-α (TNF-α), IL-6, inducible nitric oxide synthase (iNOS), and cyclooxygenase (COX)-2 in both rat chondrocytes and cell culture supernatants. Besides, IL-1β-induced degradation of aggrecan and collage II, and the high expression of matrix metalloproteinase-13 (MMP-13) and a disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS)-5 were also reversed by moracin. Moreover, moracin inhibited the translocation of p65 from the cytoplasm to nucleus induced by IL-1β and activated the Nrf2/HO-1 signaling pathway in chondrocytes. In OA rat models, moracin prevented cartilage of rats from destruction. All these findings above indicated that moracin could be a potentially effective drug for treating OA.

Food & Function published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C7H3Cl2F3O2S, Product Details of C14H10O4.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Dej-adisai, Sukanya’s team published research in Tropical Journal of Pharmaceutical Research in 15 | CAS: 56317-21-6

Tropical Journal of Pharmaceutical Research published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Computed Properties of 56317-21-6.

Dej-adisai, Sukanya published the artcileDetermination of phytochemical compounds, and tyrosinase inhibitory and antimicrobial activities of bioactive compounds from Streblus ilicifolius (s vidal) corner, Computed Properties of 56317-21-6, the publication is Tropical Journal of Pharmaceutical Research (2016), 15(3), 497-506, database is CAplus.

Purpose: To determine the phytochem. content, and tyrosinase inhibitory and antimicrobial activities of the wood from S treblus ilicifolius (S. Vidal) Corner Methods: The dried wood of S. ilicifolius (8.70 kg) was extracted by maceration to give petroleum ether, Et acetate, ethanol and water extracts, resp. Dopachrome method was used to determine antityrosinase activity. Agar disk diffusion and modified broth microdilution methods were used to determine antimicrobial activity. Chromatog. techniques were used for phytochem. investigation. The structures elucidation of isolated compounds were identified by phys. properties and spectroscopic data including UV, IR, NMR and MS data and confirmed by comparison with previously reports. Results: The ethanol extract exhibited tyrosinase inhibition and antimicrobial activity against the Grampos. bacteria, Staphylococcus epidermidis and S. aureus. Phytochem. investigation showed five compounds, namely, (E)-2,4-dihydroxy-3-(3,7-dimethyl-2,6-octadienyl) benzaldehyde (1), phydroxybenzoic acid Me ester (2), umbelliferone (3), moracin M (4), trans-resveratrol (5). Compound 4 exhibited tyrosinase inhibition with half maximal inhibitory concentration (IC50) of 67.69 μg/mL, while compound 1 displayed strong activity against S. epidermidis, S. aureus and methicillin-resistant S. aureus (MRSA) with min. inhibitory concentration (MIC) of 8, 4 and 8 μg/mL, resp. and min. bactericidal concentration (MBC) of 32, 16 and 64 μg/mL, resp. Conclusion: This is the first report of the biol. activities and phytochem. composition of S. ilicifolius and the results indicate the high potentials of the plant for com. applications such as in facial whitening and anti-acne cream.

Tropical Journal of Pharmaceutical Research published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Computed Properties of 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem