An article Photoregulated fluxional fluorophores for live-cell super-resolution microscopy with no apparent photobleaching WOS:000461311900002 published article about INTRAMOLECULAR SPIROCYCLIZATION; MOLECULES; NANOSCOPY in [Halabi, Elias A.; Rivera-Fuentes, Pablo] Swiss Fed Inst Technol, Lab Organ Chem, CH-8093 Zurich, Switzerland; [Pinotsi, Dorothea] Swiss Fed Inst Technol, Sci Ctr Opt & Electron Microscopy, CH-8093 Zurich, Switzerland in 2019, Cited 42. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. Formula: C8H6O2
Photoswitchable molecules have multiple applications in the physical and life sciences because their properties can be modulated with light. Fluxional molecules, which undergo rapid degenerate rearrangements in the electronic ground state, also exhibit switching behavior. The stochastic nature of fluxional switching, however, has hampered its application in the development of functional molecules and materials. Here we combine photoswitching and fluxionality to develop a fluorophore that enables very long (>30 min) time-lapse single-molecule localization microscopy in living cells with minimal phototoxicity and no apparent photobleaching. These long time-lapse experiments allow us to track intracellular organelles with unprecedented spatiotemporal resolution, revealing new information of the three-dimensional compartmentalization of synaptic vesicle trafficking in live human neurons.
Formula: C8H6O2. About Isobenzofuran-1(3H)-one, If you have any questions, you can contact Halabi, EA; Pinotsi, D; Rivera-Fuentes, P or concate me.