Discovery of 196799-45-8

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Bicyclic derivative inhibitor, as well as preparation method and application thereof (by machine translation)

The present invention relates to a bicyclic derivative inhibitor, a preparation method thereof and an application . and particularly, relates to a compound (I) represented by general formula, a preparation method thereof, a pharmaceutical composition, containing the compound and application A of the compound as acetyl coenzyme (Acetyl – CoA carboxylase,ACC) carboxylase, inhibitor, in the treatment of fatty acid metabolic disorders. (by machine translation)

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Benzofuran – Wikipedia,
Benzofuran | C8H1303O – PubChem

The important role of 2-Methylbenzofuran

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The effects of heteroaryl ring on the photochromism of diarylethenes with a naphthalene moiety

Three new asymmetrical naphthalene-containing diarylethenes with different heteroaryl groups have been synthesized to investigate the heteroaryl effects on their properties. The three diarylethenes exhibited distinctive photochromism with good thermal stability, which may be attributed to the different heteroaryl effects. Their cycloreversion quantum yields increased in the order of 2-methylbenzofuran < 2-methylbenzothiophene < 1,2-dimethylindole, while the cyclization quantum yields exhibited a reverse trend. Compared to indole and benzothiophene, the benzofuran moiety could effectively shift the absorption maximum to a shorter wavelength and notably enhance the cyclization quantum yield and fluorescence quantum yield of the diarylethene. The results indicated that the category of heteroaryl groups played a vital role during the process of photoisomerization of naphthalene-containing diarylethene derivatives. One of the oldest and most widely used commercial enzyme inhibitors is aspirin, COA of Formula: C9H8O, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 4265-25-2

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Benzofuran – Wikipedia,
Benzofuran | C8H316O – PubChem

Final Thoughts on Chemistry for 2-(Benzofuran-3-yl)acetic acid

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Condensed pyridine bases. Synthesis and reactions of benzofuro[2,3-c] indeno[2,1-e]-, benzothieno[2,3-c]indeno[2,1-e]-, benzofuro-[3,2-c]indeno[2,1-e] – and thieno[2,3:4?,5?]-thieno[3,2-c]indeno[2,1-e]pyridines

Condensation of hetarene carboxaldehydes with phthalide gave 2-(3-hydroxy-1-oxoinden-2-yl)benzo[b]furan and 2-(3-hydroxy-1-oxoinden-2-yl)-5- ethylthieno[2,3-b]thiophene. Starting from hetaryl acetic acids gave 3-(3-hydroxy-1-oxoinden-2-yl)benzo[b]furan and 3-(3-hydroxy-1-oxoinden-2-yl) benzo[b]thiophene. Acylation of 3-hydroxy-1-oxoinden-2-yl-substituted heterocycles using acetic anhydride in the presence of 70% HClO4 leads to the formation of pentacyclic pyrilium salts. Pentacyclic indenopyridines are prepared by treating the pyrilium salts with ammonia. The reaction of the carbonyl group in the indenopyridines with hydroxylamine, hydrazine hydrate, and in reduction using NaBH4 has been studied.

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Benzofuran – Wikipedia,
Benzofuran | C8H2680O – PubChem

Simple exploration of 4265-16-1

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Reference of 4265-16-1, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.4265-16-1, Name is Benzo[b]furan-2-carboxaldehyde, molecular formula is C9H6O2. In a article£¬once mentioned of 4265-16-1

Iridium-catalyzed Synthesis of Saturated N-Heterocycles from Aldehydes and SnAP Reagents with Continuous Flow Photochemistry

Commercially available tin amine protocol (SnAP) reagents provide a simple approach to the synthesis of a wide variety of saturated N-heterocycles from aldehydes. In this report, we disclose that the copper(II) promoter and hexafluoroisopropanol can be replaced by photocatalytic conditions using Ir[dF(CF3)ppy]2(dtbbpy)PF6 in CH3CN. Continuous flow photochemical conditions provide a clean, scalable approach to valuable products including morpholines, piperazines, thiomorpholines, diazepanes, and oxazepanes from aldehyde starting materials.

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Benzofuran – Wikipedia,
Benzofuran | C8H871O – PubChem

Awesome and Easy Science Experiments about Benzofuran-3-carbaldehyde

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Palladium-catalyzed asymmetric benzylation of 3-aryl oxindoles

Herein we report palladium-catalyzed asymmetric benzylic alkylation with 3-aryl oxindoles as prochiral nucleophiles. Proceeding analogously to asymmetric allylic alkylation, asymmetric benzylation occurs in high yield and enantioselectivity for a variety of unprotected 3-aryl oxindoles and benzylic methyl carbonates using chiral bisphosphine ligands. This methodology represents a novel asymmetric carbon-carbon bond formation between a benzyl group and a prochiral nucleophile to generate a quaternary center.

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Benzofuran – Wikipedia,
Benzofuran | C8H1216O – PubChem

Simple exploration of 652-39-1

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MACROCYCLIC HEPATITIS C PROTEASE INHIBITORS

The present invention provides novel macrocyclic compounds that mimic peptide substrates of the hepatitis C viral protease and inhibit the viral protease, more particularly as inhibitors of the NS3 serine protease from hepatitis C virus. Methods for synthesis of the compounds are also provided. The compounds find utility as antiviral agents directed at hepatitis C. The invention further provides methods of employing such inhibitors, alone or in combination with other therapeutic agents, to treat hepatitis C infection in a subject in need of such treatment.

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Benzofuran – Wikipedia,
Benzofuran | C8H2464O – PubChem

Awesome Chemistry Experiments For 519018-52-1

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NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF

A compound represented by the formula (I): wherein each symbol is as defined in the specification, and a salt thereof have a GPR40 receptor activation action and is useful as an insulin secretagogue or a prophylactic or therapeutic drug for diabetes and the like

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Benzofuran – Wikipedia,
Benzofuran | C8H3592O – PubChem

Extracurricular laboratory:new discovery of Benzo[b]furan-2-carboxaldehyde

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Radical Cation Cyclopropanations via Chromium Photooxidative Catalysis

The chromium photocatalyzed cyclopropanation of diazo reagents with electron-rich alkenes is described. The transformation occurs under mild conditions and features specific distinctions from traditional diazo-based cyclopropanations (e.g., avoiding beta-hydride elimination, chemoselectivity considerations, etc.). The reaction appears to work most effectively using chromium catalysis, and a number of decorated cyclopropanes can be accessed in generally good yields.

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Benzofuran – Wikipedia,
Benzofuran | C8H1029O – PubChem

Simple exploration of 4-Fluoroisobenzofuran-1,3-dione

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BENZODIOXANE DERIVATIVES AND THEIR PHARMACEUTICAL USE

Compounds of formula (I): wherein Ra and Rb are as defined in the claims, exhibit alpha2C antagonistic activity and are thus useful as alpha2C antagonists.

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Benzofuran – Wikipedia,
Benzofuran | C8H2481O – PubChem

Awesome Chemistry Experiments For 1563-38-8

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Related Products of 1563-38-8, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1563-38-8, Name is 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol, molecular formula is C10H12O2. In a Patent£¬once mentioned of 1563-38-8

A g budweiser carboxylated semi-antigenic synthetic method of (by machine translation)

The invention “a g budweiser carboxylated semi-antigen synthesis method”, relates to a bio-chemical technology. This invention is a novel Kebaiwei carboxylated semi-antigen synthesis method, the synthesis step is simple and effective, high yield, avoiding the traditional triphosgene synthesis method for use in a large amount the harmfulness of phosgene and toluene. In order to the benzofuranol as the starting material, the reaction of esterification and aminolysis, introduce a containing 4 arm chain the carboxy-terminus of the carbon and, forming carboxylated semi-antigen. The artificial antigen preparation Kebaiwei active ester method, ultraviolet-visible spectroscopy scanning and immune animal experiment shows that good preparation of the present invention the immunogenicity of the antigen. Hapten and of the invention can be totally used in artificial antigen immune analysis Kebaiwei, to meet the domestic needs of the detection of the residual budweiser 6g, application prospect. (by machine translation)

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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H2326O – PubChem