The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 6-Fluoronicotinonitrile(SMILESS: N#CC1=CC=C(F)N=C1,cas:3939-12-6) is researched.COA of Formula: C6H4O3. The article 《Arylation, Vinylation, and Alkynylation of Electron-Deficient (Hetero)arenes Using Iodonium Salts》 in relation to this compound, is published in Organic Letters. Let’s take a look at the latest research on this compound (cas:3939-12-6).
Arylation, vinylation, and alkynylation of electron-deficient arenes and heteroarenes have been achieved by chemoselective C-H zincation followed by copper-catalyzed coupling reactions using iodonium salts. This approach offers a direct and general access to a wide scope of (hetero)biaryls as well as alkenylated and alkynylated heteroarenes under mild conditions. It is particularly useful and valuable for the rapid and modular synthesis of diverse (hetero)aryl compounds, as demonstrated in the synthesis of transient receptor potential vanilloid 1 (TRPV1) antagonists and angiotensin II receptor type 1 (AT1 receptor) antagonists.
Compound(3939-12-6)COA of Formula: C6H3FN2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(6-Fluoronicotinonitrile), if you are interested, you can check out my other related articles.
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem