Tag: 610-93-5

610-93-5, 6-Nitroisobenzofuran-1(3H)-one is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,610-93-5

General procedure: The catalytic reduction of nitro aromatics was conducted in a 25 mlTelfon-lined stainless steel autoclave with magnetic stirring. In a typicalprocess, 6 mmol nitroarene, and desired amounts of reducing agent andsolvents were introduced in the reactor. The autoclave was transferredinto a water bath at the set temperature with an accuracy of better than0.2 C for ?0.5 h. Then, 10 mg catalyst was added into the reactionmixture and started the reduction at a stirring rate of 450 rpm. After thereaction, the catalyst was rapidly separated by ltration. n-Decane(500 muL) as standard was added into the ltrate and was dried withanhydrous Na 2 SO 4 . The products were analyzed by gas chromato-graphy-mass spectrometry (GC-MS) (Shimadzu GCMS-QP2010 Plus)and GC (Varian CP-3800) with a capillary column (column VF-1 ms,15 m, 0.25 mm, 0.25 mum) and a ame ionization detector (FID).

The synthetic route of 610-93-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Huang, Haigen; Liang, Xiangcheng; Wang, Xueguang; Sheng, Yao; Chen, Chenju; Zou, Xiujing; Lu, Xionggang; Applied Catalysis A: General; vol. 559; (2018); p. 127 – 137;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem

610-93-5, 6-Nitroisobenzofuran-1(3H)-one is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of compounds 12 (10 mmol) and 10% (mass fraction) Pd/C (0.20 g) in MeOH (20 mL) was subjected to standard hydrogenolysis condition at atmospheric pressure (balloon) and room temperature. The progress of the reaction was monitored by TLC. After completion of the reactions, the reaction mixture was filtered off and the filtrate was evaporated on a rotary evaporator to afford the crude products 13, which were used directly in the next step without further purification. Yield: 87%, Mp: 186-187 C. 1H-NMR (CDCl3, 600 MHz), d: 7.28(s, 1H, ArH), 7.11-7.07(m, 1H, ArH), 7.05(dd, J = 8.1Hz, 2.1Hz, 1H, ArH), 5.25(s, 2H), 3.95(s, 2H, NH2). 5110 X. Hu et al. 123

The synthetic route of 610-93-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Hu, Xia-min; Cui, Zhi-wen; Dong, Wei; Zhu, Yue; Gao, Cheng-zhi; Xu, Shi-qiang; Yuan, Qiong; Yu, Zhi-jun; Min, Zhen-li; Research on Chemical Intermediates; vol. 44; 9; (2018); p. 5107 – 5122;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem

610-93-5, 6-Nitroisobenzofuran-1(3H)-one is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To a screw top vial (5 mL) under N2 containing freshly distilled toluene (0.6 mL) were successively added an aromatic nitro compound (0.60 mmol), InI3 (14.9 mg, 0.030 mmol), and TMDS (318 muL, 1.80 mmol). After the vial was sealed with a cap that contained a PTFE septum, the mixture was stirred at 60 C (bath temperature), and monitored via TLC analysis. Sat. aq NaHCO3 solution (5 mL) was added to the resultant mixture, which was then extracted with EtOAc (3 ¡Á 6 mL). The combined organic phases were dried over anhydrous Na2SO4, filtered, and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (n-hexane-EtOAc, 9:1 to 4:1) to afford the corresponding aniline derivative.

As the paragraph descriping shows that 610-93-5 is playing an increasingly important role.

Reference£º
Article; Sakai, Norio; Asama, Shun; Konakahara, Takeo; Ogiwara, Yohei; Synthesis; vol. 47; 20; (2015); p. 3179 – 3185;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem