Tag: 244.094

Yao, Wubing et al. published their research in Organometallics in 2016 | CAS: 519054-55-8

2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Reference of 519054-55-8

Cobalt-catalyzed borylation of aryl halides and pseudohalides was written by Yao, Wubing;Fang, Huaquan;Peng, Sihan;Wen, Huanan;Zhang, Lei;Hu, Aiguo;Huang, Zheng. And the article was included in Organometallics in 2016.Reference of 519054-55-8 This article mentions the following:

We report the first Co-catalyzed borylation of aryl halides and pseudohalides with bis(pinacolato)diboron (B2pin2). The synthesis of two new Co(II) complexes of oxazolinylferrocenylphosphine ligands 1-R2P-2-(4-Me-2-Ox) (2-Ox = 2-oxazolinyl; L1, R = Ph, L2, R = iPr) and their cobalt complexes [(Ln)CoCl2] (2a, R = Ph, 2b, R = iPr) is described. Crystal structures of 2a,b were determined Upon activation with LiMe, the Co complex catalyzes the borylation reactions of aryl bromides, iodides, sulfonates, arenediazonium salts, and even aryl chlorides under mild conditions, providing the borylated products ArBpin in excellent to moderate yields and with high functional group tolerance. In the experiment, the researchers used many compounds, for example, 2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8Reference of 519054-55-8).

2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Reference of 519054-55-8

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Liu, Yunxia et al. published their research in Organic Letters in 2022 | CAS: 519054-55-8

2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Application of 519054-55-8

Electromagnetic Mill Promoted Mechanochemical Solvent-Free Palladium-Catalyzed Borylation of Aryl Bromides was written by Liu, Yunxia;Li, Xin;Liu, Qing;Li, Xinjin;Liu, Hui. And the article was included in Organic Letters in 2022.Application of 519054-55-8 This article mentions the following:

The electromagnetic mill (EMM) promoted mechanochem. solvent-free Pd-catalyzed borylation of aryl bromides using low Pd catalyst loading (0.05-0.5 mol %) was realized. This protocol exhibits many advantages, such as broad substrate scope, good functional group tolerance, short reaction times, no addnl. heating, and practical gram-scale synthesis. This EMM system not only showed excellent prospects for industrial application but also unlocked broad areas of solvent-free solid-state metal-catalyzed syntheses. In the experiment, the researchers used many compounds, for example, 2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8Application of 519054-55-8).

2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Application of 519054-55-8

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Jin, Shengfei et al. published their research in Journal of the American Chemical Society in 2020 | CAS: 519054-55-8

2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.COA of Formula: C14H17BO3

Visible Light-Induced Borylation of C-O, C-N, and C-X Bonds was written by Jin, Shengfei;Dang, Hang. T.;Haug, Graham C.;He, Ru;Nguyen, Viet D.;Nguyen, Vu T.;Arman, Hadi D.;Schanze, Kirk S.;Larionov, Oleg V.. And the article was included in Journal of the American Chemical Society in 2020.COA of Formula: C14H17BO3 This article mentions the following:

Aryl phosphates, arylammonium salts and aryl halides were borylated with B2pin2 in photochem. substitution reaction catalyzed by phenothiazines, yielding aryl pinacolboranes and aryltrifluoroborates. Boronic acids are centrally important functional motifs and synthetic precursors. Visible light-induced borylation may provide access to structurally diverse boronates, but a broadly efficient photocatalytic borylation method that can effect borylation of a wide range of substrates, including strong C-O bonds, remains elusive. Herein, we report a general, metal-free visible light-induced photocatalytic borylation platform that enables borylation of electron-rich derivatives of phenols and anilines, chloroarenes, as well as other haloarenes. The reaction exhibits excellent functional group tolerance, as demonstrated by the borylation of a range of structurally complex substrates. Remarkably, the reaction is catalyzed by phenothiazine, a simple organic photocatalyst with MW < 200 that mediates the previously unachievable visible light-induced single electron reduction of phenol derivatives with reduction potentials as neg. as approx. – 3 V vs. SCE by a proton-coupled electron transfer mechanism. Mechanistic studies point to the crucial role of the photocatalyst-base interaction. In the experiment, the researchers used many compounds, for example, 2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8COA of Formula: C14H17BO3).

2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.COA of Formula: C14H17BO3

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Jin, Shengfei et al. published their research in Journal of the American Chemical Society in 2020 | CAS: 519054-55-8

2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.COA of Formula: C14H17BO3

Visible Light-Induced Borylation of C-O, C-N, and C-X Bonds was written by Jin, Shengfei;Dang, Hang. T.;Haug, Graham C.;He, Ru;Nguyen, Viet D.;Nguyen, Vu T.;Arman, Hadi D.;Schanze, Kirk S.;Larionov, Oleg V.. And the article was included in Journal of the American Chemical Society in 2020.COA of Formula: C14H17BO3 This article mentions the following:

Aryl phosphates, arylammonium salts and aryl halides were borylated with B2pin2 in photochem. substitution reaction catalyzed by phenothiazines, yielding aryl pinacolboranes and aryltrifluoroborates. Boronic acids are centrally important functional motifs and synthetic precursors. Visible light-induced borylation may provide access to structurally diverse boronates, but a broadly efficient photocatalytic borylation method that can effect borylation of a wide range of substrates, including strong C-O bonds, remains elusive. Herein, we report a general, metal-free visible light-induced photocatalytic borylation platform that enables borylation of electron-rich derivatives of phenols and anilines, chloroarenes, as well as other haloarenes. The reaction exhibits excellent functional group tolerance, as demonstrated by the borylation of a range of structurally complex substrates. Remarkably, the reaction is catalyzed by phenothiazine, a simple organic photocatalyst with MW < 200 that mediates the previously unachievable visible light-induced single electron reduction of phenol derivatives with reduction potentials as neg. as approx. – 3 V vs. SCE by a proton-coupled electron transfer mechanism. Mechanistic studies point to the crucial role of the photocatalyst-base interaction. In the experiment, the researchers used many compounds, for example, 2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8COA of Formula: C14H17BO3).

2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.COA of Formula: C14H17BO3

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem