Electromagnetic Mill Promoted Mechanochemical Solvent-Free Palladium-Catalyzed Borylation of Aryl Bromides was written by Liu, Yunxia;Li, Xin;Liu, Qing;Li, Xinjin;Liu, Hui. And the article was included in Organic Letters in 2022.Application of 519054-55-8 This article mentions the following:
The electromagnetic mill (EMM) promoted mechanochem. solvent-free Pd-catalyzed borylation of aryl bromides using low Pd catalyst loading (0.05-0.5 mol %) was realized. This protocol exhibits many advantages, such as broad substrate scope, good functional group tolerance, short reaction times, no addnl. heating, and practical gram-scale synthesis. This EMM system not only showed excellent prospects for industrial application but also unlocked broad areas of solvent-free solid-state metal-catalyzed syntheses. In the experiment, the researchers used many compounds, for example, 2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8Application of 519054-55-8).
2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Application of 519054-55-8
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem