Category: 519054-55-8

Yao, Wubing et al. published their research in Organometallics in 2016 | CAS: 519054-55-8

2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Reference of 519054-55-8

Cobalt-catalyzed borylation of aryl halides and pseudohalides was written by Yao, Wubing;Fang, Huaquan;Peng, Sihan;Wen, Huanan;Zhang, Lei;Hu, Aiguo;Huang, Zheng. And the article was included in Organometallics in 2016.Reference of 519054-55-8 This article mentions the following:

We report the first Co-catalyzed borylation of aryl halides and pseudohalides with bis(pinacolato)diboron (B2pin2). The synthesis of two new Co(II) complexes of oxazolinylferrocenylphosphine ligands 1-R2P-2-(4-Me-2-Ox) (2-Ox = 2-oxazolinyl; L1, R = Ph, L2, R = iPr) and their cobalt complexes [(Ln)CoCl2] (2a, R = Ph, 2b, R = iPr) is described. Crystal structures of 2a,b were determined Upon activation with LiMe, the Co complex catalyzes the borylation reactions of aryl bromides, iodides, sulfonates, arenediazonium salts, and even aryl chlorides under mild conditions, providing the borylated products ArBpin in excellent to moderate yields and with high functional group tolerance. In the experiment, the researchers used many compounds, for example, 2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8Reference of 519054-55-8).

2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Reference of 519054-55-8

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Liu, Yunxia et al. published their research in Organic Letters in 2022 | CAS: 519054-55-8

2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Application of 519054-55-8

Electromagnetic Mill Promoted Mechanochemical Solvent-Free Palladium-Catalyzed Borylation of Aryl Bromides was written by Liu, Yunxia;Li, Xin;Liu, Qing;Li, Xinjin;Liu, Hui. And the article was included in Organic Letters in 2022.Application of 519054-55-8 This article mentions the following:

The electromagnetic mill (EMM) promoted mechanochem. solvent-free Pd-catalyzed borylation of aryl bromides using low Pd catalyst loading (0.05-0.5 mol %) was realized. This protocol exhibits many advantages, such as broad substrate scope, good functional group tolerance, short reaction times, no addnl. heating, and practical gram-scale synthesis. This EMM system not only showed excellent prospects for industrial application but also unlocked broad areas of solvent-free solid-state metal-catalyzed syntheses. In the experiment, the researchers used many compounds, for example, 2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8Application of 519054-55-8).

2-(Benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 519054-55-8) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Application of 519054-55-8

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem