Tag: 200-300

Harada, Nobuyuki; Masuda, Kiyoshi; Nakamura, Jun-ich; Uyama, Hiroshi published their research in Polymer Journal (Tokyo, Japan) in 2021. The article was titled 《Fabrication and evaluation of durable, optically clear, and self-disinfecting films》.Name: 1,3-Diphenylisobenzofuran The article contains the following contents:

Phenoxy-substituted phthalocyanine zinc (PPcZn) was synthesized and used as a photosensitizer to prepare a variety of self-disinfecting films by incorporating it into a cellulose acetate (CA) film at various concentrations The generation of singlet oxygen (1O2) from the films containing PPcZn irradiated with visible light was detected by a film containing 1,3-diphenylisobenzofuran (DPBF). The rate of 1O2 generation followed a pseudofirst-order kinetic model. Antiviral activity was confirmed under visible light irradiation using Bacteriophage Qβ. The film exhibited superior water resistance, photostability, mech. strength, and sustained 1O2 production over 6 mo under continuous exposure to room light. These data show the promise of this film in real-life applications as self-disinfecting surfaces. In addition to this study using 1,3-Diphenylisobenzofuran, there are many other studies that have used 1,3-Diphenylisobenzofuran(cas: 5471-63-6Name: 1,3-Diphenylisobenzofuran) was used in this study.

1,3-Diphenylisobenzofuran(cas: 5471-63-6) can be used as a fluorescent probe for detection of superoxide anion radical (O2−) inside the membrane lipid layer by DPBF fluorescence quenching method. 1,3-Diphenylisobenzofuran(DPBF) can be used to study the single crystal molecular structure and solution photophysical properties of DPBF.Name: 1,3-Diphenylisobenzofuran

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Sapkal, Suryakant B.; Shelke, Kiran F.; Shingate, Bapurao B.; Shingare, Murlidhar S. published their research in Chinese Chemical Letters on December 31 ,2010. The article was titled 《An efficient synthesis of benzofuran derivatives under conventional/non-conventional method》.Formula: C12H12O4 The article contains the following contents:

1-Methyl-3-Et imidazolium bromide [meim]Br/basic alumina (Al2O3) has been found to promote the cyclocondensation of chloroacetone/chloroethyl acetate with salicylaldehydes under conventional as well as microwave irradiation to yield benzofuran derivatives, e.g. I (R = Me, OEt). In the part of experimental materials, we found many familiar compounds, such as Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0Formula: C12H12O4)

Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0) belongs to benzofurans.Formula: C12H12O4Benzofurans containing one furan ring that have been implicated as psychoactive recreational drugs include 6-(2-aminopropyl)benzofuran (6-APB), 5-(2-aminopropyl)benzofuran (5-APB), 5-(2-ethylaminopropyl)benzofuran (5-EAPB), and 5-methylaminopropylbenzofuran (5-MAPB).

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Wang, Xiao-Hui; Wei, Xiao-Fei; Liu, Jin-Hua; Yang, Wei; Liu, Yuan-An; Cheng, Kun; He, Xiao-Ying; Fu, Xiu-Li; Zhang, Yu; Zhang, Hong-Xin published an article in 2021. The article was titled 《Chlorin e6-1,3-diphenylisobenzofuran polymer hybrid nanoparticles for singlet oxygen-detection photodynamic abaltion》, and you may find the article in Methods and Applications in Fluorescence.Recommanded Product: 5471-63-6 The information in the text is summarized as follows:

Adual-functional nanosysterm is developed by means of Chlorin e6 (Ce6) as photosensitizer and 1,3- Diphenylisobenzofuran (DPBF) as fluorescent singlet oxygen (1O2) probe. Under 660 nmlaser irradation, Ce6 exhibites efficient 1O2 generation, and subsequently the production of 1O2 is assessed by the ratiometric fluorescence of PFO and DPBF under one-photon and two-photon excitation mode. The nanoparticles with excellent biocompatibility can be internalized into Hela cells and applied for tumor treatment. For intracellular PDT, the nanoparticles perform a high phototoxicity, while the PDT proccess can be evaluated in time by monitoring fluorescence signals of DPBF. This theranostic nanosysterm provides a facile strategy to fabricate 1O2-detection PDT, which can realize accurate and efficient photodynamic therapy based on singlet oxygen detection. In the part of experimental materials, we found many familiar compounds, such as 1,3-Diphenylisobenzofuran(cas: 5471-63-6Recommanded Product: 5471-63-6)

1,3-Diphenylisobenzofuran(cas: 5471-63-6) can be used as a fluorescent probe for detection of superoxide anion radical (O2−) inside the membrane lipid layer by DPBF fluorescence quenching method. 1,3-Diphenylisobenzofuran(DPBF) can be used as quencher during the photoinactivation of TA-3 mouse mammary carcinoma cells containing hematoporphyrin.Recommanded Product: 5471-63-6

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

HPLC of Formula: 50551-57-0On October 1, 2010 ,《Novel imidazoline compounds as partial or full agonists of D2-like dopamine receptors inspired by I2-imidazoline binding sites ligand 2-BFI》 was published in Bioorganic & Medicinal Chemistry. The article was written by Giorgioni, Gianfabio; Ambrosini, Dario; Vesprini, Cristian; Hudson, Alan; Nasuti, Cinzia; Di Stefano, Antonio; Sozio, Piera; Ciampi, Osele; Costa, Barbara; Martini, Claudia; Carrieri, Antonio; Carbonara, Giuseppe; Enzensperger, Christoph; Pigini, Maria. The article contains the following contents:

Based on the well known biol. versatility of the imidazoline nucleus, we prepared the novel derivatives 3a-k inspired by 2-BFI scaffold to assess imidazoline mols. as D2-like dopamine receptor ligands. Conservative chem. modifications of the lead structure, such as the introduction of an hydroxy group in the aromatic ring alone or associated with N-benzyl substitution, provided partial (3f)(I) or nearly full (3e and 3h) agonists, all endowed with D2-like potency comparable to that of dopamine. The experimental part of the paper was very detailed, including the reaction process of Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0HPLC of Formula: 50551-57-0)

Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0) belongs to benzofurans.HPLC of Formula: 50551-57-0Benzofurans containing one furan ring that have been implicated as psychoactive recreational drugs include 6-(2-aminopropyl)benzofuran (6-APB), 5-(2-aminopropyl)benzofuran (5-APB), 5-(2-ethylaminopropyl)benzofuran (5-EAPB), and 5-methylaminopropylbenzofuran (5-MAPB).

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

COA of Formula: C12H12O4On October 15, 2008 ,《Aminostyrylbenzofuran derivatives as potent inhibitors for Aβ fibril formation》 was published in Bioorganic & Medicinal Chemistry Letters. The article was written by Byun, Ji Hun; Kim, HyeYun; Kim, YoungSoo; Mook-Jung, Inhee; Kim, Dong Jin; Lee, Won Koo; Yoo, Kyung Ho. The article contains the following contents:

The synthesis of a novel series of aminostyrylbenzofurans I (R1, R2 = H, Br, Cl, F, I, OH, OMe; R3 = NH2, NHMe, NMe2; R4 = H, OMe) and their inhibitory activities for Aβ fibril formation were described. All the synthesized compounds were evaluated by thioflavin T (ThT) assay and displayed potent inhibitory activities for Aβ fibril formation. Among them, compounds I (R1 = R4 = H; R2 = OMe; R3 = NMe2) and I (R1 = OMe, R2 = R4 = H; R3 = NHMe) exhibited excellent inhibitory activities (IC50 = 0.07 and 0.08 μM, resp.) than those of Curcumin (IC50 = 0.80 μM) and IMSB (IC50 = 8.00 μM) as reference compounds Both compounds were selected as promising candidates for further biol. evaluation. In the part of experimental materials, we found many familiar compounds, such as Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0COA of Formula: C12H12O4)

Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0) belongs to benzofurans.COA of Formula: C12H12O4Benzofurans containing one furan ring that have been implicated as psychoactive recreational drugs include 6-(2-aminopropyl)benzofuran (6-APB), 5-(2-aminopropyl)benzofuran (5-APB), 5-(2-ethylaminopropyl)benzofuran (5-EAPB), and 5-methylaminopropylbenzofuran (5-MAPB).

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

《Gold nanoshells coated 5-aminolevulinic liposomes for photothermal-photodynamic antitumor therapy》 was written by Jiang, Yifei; Liu, Yang; Fang, Siyuan; Ji, Min. SDS of cas: 5471-63-6 And the article was included in Journal of Nanoscience and Nanotechnology in 2020. The article conveys some information:

In this study, a novel antitumor system was designed on the basis of photodynamic therapy and photothermal therapy using gold nanoshells coated 5-aminolevulinic acid (5-ALA) liposomes (GNALs). As a widely used photosensitizer prodrug, 5-aminolevulinic acid (5-ALA)-derived protoporphyrin IX (PpIX) can accumulate to a higher level in tumors than in normal tissues. Protoporphyrin IX (PpIX) initiates a series of cytotoxic reactions after irradiation of target tissue with a measured dose of light with appropriate wavelength, which may be dependent on the generation of reactive oxygen species. Gold nanoshells can strongly absorb NIR lasers at the same time, and can generate hyperthermia to provide photothermic effects. Gold nanoshells coated 5-ALA-Liposomes (GNALs) exhibit a uniform-sized spherical shape of 185.8±0.91 nm, with a zeta potential of 33±1.6 mV. Liposomes with specific sizes ranging from 100 to 200 nm can escape into the tumor interstitial tissue and accumulate preferentially in tumor tissue owing to the EPR effect. In addition, NIR light-excited nanosystems significantly promoted antitumor effects in this study compared to single photodynamic therapy. It was also found that the increased temperature promoted inhibition rate of SKOV3 cells. The novel drug delivery system shows great potential in photothermal-photodynamic antitumor therapy. In the experiment, the researchers used 1,3-Diphenylisobenzofuran(cas: 5471-63-6SDS of cas: 5471-63-6)

1,3-Diphenylisobenzofuran(cas: 5471-63-6) can be used as a fluorescent probe for detection of superoxide anion radical (O2−) inside the membrane lipid layer by DPBF fluorescence quenching method. 1,3-Diphenylisobenzofuran(DPBF) can be used as quencher during the photoinactivation of TA-3 mouse mammary carcinoma cells containing hematoporphyrin.SDS of cas: 5471-63-6

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

The author of 《Benzofurans. LIV. New access to hydroxybenzofurans》 were Rene, Loic; Royer, Rene. And the article was published in Bulletin de la Societe Chimique de France in 1973. Category: benzofurans The author mentioned the following in the article:

Hydroxybenzofurans were prepared in overall yields I 70, II 60, III 30, IV 55%, by cyclizing methoxysalicylaldehydes with ClCH2CO2Et to a mixture of Et methoxycoumarilate, methoxycoumarilic acid, and methoxybenzofuran. The coumarilic acid derivatives were decarboxylated with Cu in quinoline and the methoxybenzofurans were demethylated by pyridine-HCl. The experimental process involved the reaction of Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0Category: benzofurans)

Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0) belongs to benzofurans.Category: benzofuransBenzofurans containing one furan ring that have been implicated as psychoactive recreational drugs include 6-(2-aminopropyl)benzofuran (6-APB), 5-(2-aminopropyl)benzofuran (5-APB), 5-(2-ethylaminopropyl)benzofuran (5-EAPB), and 5-methylaminopropylbenzofuran (5-MAPB).

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

In 1975,Bulletin de la Societe Chimique de France included an article by Rene, Loic; Buisson, Jean P.; Royer, Rene. Application In Synthesis of Ethyl 6-methoxybenzofuran-2-carboxylate. The article was titled 《Reactions induced by pyridinium halides. XX. First examples of dealkylation by pyridinium hydrochloride in quinoline》. The information in the text is summarized as follows:

Benzofuranols I-VI (R = R1 = H, R2 = H, Me) were prepared in improved yields by demethylating I-VI (R1 = Me) with pyridine-HCl in quinoline. I-VI (R1 = Me) were prepared by formylating coumarilic acid esters, hydrolyzing I-VI (R = CO2Me, CO2Et, R1 = Me), and decarboxylating I-VI (R = CO2H). In addition to this study using Ethyl 6-methoxybenzofuran-2-carboxylate, there are many other studies that have used Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0Application In Synthesis of Ethyl 6-methoxybenzofuran-2-carboxylate) was used in this study.

Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0) belongs to benzofurans.Application In Synthesis of Ethyl 6-methoxybenzofuran-2-carboxylateBenzofurans containing one furan ring that have been implicated as psychoactive recreational drugs include 6-(2-aminopropyl)benzofuran (6-APB), 5-(2-aminopropyl)benzofuran (5-APB), 5-(2-ethylaminopropyl)benzofuran (5-EAPB), and 5-methylaminopropylbenzofuran (5-MAPB).

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

《A bacteria-triggered wearable colorimetric band-aid for real-time monitoring and treating of wound healing》 was written by Dong, Mengna; Sun, Xinyu; Li, Lihua; He, Kunyi; Wang, Jiao; Zhang, Hui; Wang, Li. Computed Properties of C20H14OThis research focused onwearable colorimetric band aid wound healing bacterial infection; Film-based band-aid; PDT/PTT; Wearable; Wound healing; pH-sensing. The article conveys some information:

Early diagnosis of bacterial infection and tracking of treatment effect are of great importance for developing a “”sense-and-treat”” integrated system. Herein, we developed a bacteria-triggered, portable, wearable and colorimetric film-based band-aid (FBA) for closed-loop monitoring and light-controlled therapy of wound infection. FBA with high photothermal conversion efficiency of 52.56% was prepared by wrapping Bi2S3 nanoflowers (BS NFs) loaded with rhodium nanoparticles (Rh NPs) and bromothymol blue (BTB) into LB agar film, integrating bacteria-triggered color change, photothermal/photodynamic therapy (PTT/PDT) synergistic bactericidal therapy and agar-based band aid in one intelligent system. Initially, FBA effectively simulates the pH sensing mechanism, and monitors the occurrence of bacterial infections within 5 min through color changes of Staphylococcus aureus (S. aureus) from blue to yellow and Escherichia coli (E. coli) from yellow to blue. Addnl., the short-term and controlled antibacterial strategy of “”one light dual-mode responses”” (photothermal and photodynamic responses) was implemented with the introduce of near-IR (NIR). Ultimately, the effectiveness of FBA was fully validated in the monitoring and treating of S. aureus-infected mouse wounds. Notably, the designed FBA decisively abandoned off-target side effects maximizing the treatment effect and nakedly tracking therapeutic situation in real time, contributing an effective antibacterial alternative strategy for reducing the use of antibiotics. To the best of our knowledge, such integrated system is still unreported on film-fixed model. In view of the advantages of the low cost and convenience of the simple device, the integrated design is expected to provide a solution for the development of a closed-loop biomedical system combining diagnosis and treatment. In the experimental materials used by the author, we found 1,3-Diphenylisobenzofuran(cas: 5471-63-6Computed Properties of C20H14O)

1,3-Diphenylisobenzofuran(cas: 5471-63-6) is a fluorescent dye. 1,3-Diphenylisobenzofuran is the model compound in studies of singlet fission.Computed Properties of C20H14O

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

In 2022,Wang, Ya-Ning; Zhang, Wen-Shu; Liu, Xiao-Peng; Wei, Yun-Yun; Xu, Zhang-Run published an article in Colloids and Surfaces, B: Biointerfaces. The title of the article was 《A nanohybrid of Prussian blue supported by boracic acid-modified g-C3N4 for Raman recognition of cell surface sialic acid and photothermal/photodynamic therapy》.SDS of cas: 5471-63-6 The author mentioned the following in the article:

Theranostic nanoplatforms with accurate diagnosis and effective therapy show a bright prospect for tumor treatments. Herein, a novel boracic acid-modified graphite carbon nitride and Prussian blue nanohybrid (PB@B-g-3N4) was developed, which provides sialic acid-targeted Raman recognition and synergistic photothermal/photodynamic therapy in the near-IR region. Owing to the specific interaction between boracic acid and sialic acid and Raman response at 2157 cm-1 of PB, the nanohybrids exhibit high specificity and Raman sensitivity for detection of the overexpressed sialic acid on tumor cells. Moreover, the photothermal conversion efficiency of PB@B-g-3N4 is as high as 47.0% with 808 nm laser irradiation due to the enhanced absorbance of PB@B-g-3N4. PB@B-g-3N4 also possesses excellent photodynamic activity, which is attributed to the energy transfer of PB (type I) and electron transfer between PB and B-g-3N4 (type II). This nanotheranostic agent for Raman recognition of cancer markers and synergistic photothermal/photodynamic therapy holds great potential for the development of efficient theranostic nanoplatforms. The experimental part of the paper was very detailed, including the reaction process of 1,3-Diphenylisobenzofuran(cas: 5471-63-6SDS of cas: 5471-63-6)

1,3-Diphenylisobenzofuran(cas: 5471-63-6) can be used as a fluorescent probe for detection of superoxide anion radical (O2−) inside the membrane lipid layer by DPBF fluorescence quenching method. 1,3-Diphenylisobenzofuran(DPBF) can be used as quencher during the photoinactivation of TA-3 mouse mammary carcinoma cells containing hematoporphyrin.SDS of cas: 5471-63-6

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem