Tag: 200-300

Direct amine-functionalization of γ-Fe₂O₃ nanoparticles was written by Rocher, V.;Manerova, J.;Kinnear, M.;Evans, D. J.;Francesconi, M. G.. And the article was included in Dalton Transactions in 2014.Related Products of 38183-12-9 This article mentions the following:

A novel and simple preparation of amine-modified γ-Fe₂O₃ nanoparticles is described. The presence of amine groups on the surface, instead of hydroxyl groups, will allow conjugation of biol. active mols. to the Fe oxide nanoparticles without the need for a size increasing SiO₂ shell. Also, the outer amine-layer increases the temperature of the γ-Fe₂O₃ to α-Fe₂O₃ structural transition in a similar way to previously reported cationic substitutions. This may suggest the formation of an oxide-nitride outer layer. Re-dispersion of the amine-modified γ-Fe₂O₃ nanoparticles gave stable ferrofluids. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Related Products of 38183-12-9).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Related Products of 38183-12-9

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Development of luminol-fluorescamine-PVP chemiluminescence system and its application to sensitive tyrosinase determination was written by Wang, Chao;Chen, Yequan;Snizhko, Dmytro;Du, Fangxin;Ma, Xiangui;Lou, Baohua;Li, Jianping;Xu, Guobao. And the article was included in Talanta in 2020.COA of Formula: C17H10O4 This article mentions the following:

Fluorescamine is a popular fluorescent probe. We report for the first time that luminol chemiluminescence (CL) can be enhanced by fluorescamine in the presence of PVP. The CL intensity of luminol-fluorescamine-PVP is about 26 times stronger than that of luminol. Both the removal of oxygen and the addition of superoxide dismutase (SOD) decrease CL intensity, thiourea and NaN₃ have little effect on CL intensities, indicating that O^â€?₂ is critical for CL. Interestingly, o-quinone generated from phenol by tyrosinase obviously inhibited the CL intensity. Inspired by such quenching effect on the luminol-fluorescamine-PVP CL system, a sensitive CL sensing for the determination of tyrosinase activity was developed. The method can detect tyrosinase in the range of 0.07-1.5μg mL^-1 (0.19-4.02 U mL^-1) with the detection limit of 0.035μg mL^-1 (0.094 U mL^-1). Moreover, this method exhibits satisfied recoveries for the spiked human serum samples. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9COA of Formula: C17H10O4).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.COA of Formula: C17H10O4

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Fluorescamine-based fluorophore for spectrofluorimetric determination of heptaminol in human plasma; application to spiked human plasma was written by Omar, Mahmoud A.;Nagy, Dalia M.;Halim, Monica E.. And the article was included in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 2020.Safety of 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione This article mentions the following:

An innovative approach to determine heptaminol spectrofluorimetrically was developed, determining the optimum conditions needed, then validated for determination of heptaminol in its pure form, its tablets and in spiked human plasma. The presented method is based on the reaction between fluorescamine reagent with the primary amine group found in heptaminol, using a borate buffer at pH 9.0 that yields a highly fluorescent product, fluorescence was measured at 471 nm after excitation at 393 nm. The linearity of the constructed calibration curve was (75-850 ng/mL) with LOD and LOQ values 23.85 and 72.29 ng/mL resp. The method was validated following the International Council for Harmonisation (ICH) guidelines indicating good accuracy and precision. Finally, the presented approach was adapted for in vitro study of heptaminol in spiked human plasma with a mean percentage recovery 100.52 ± 1.19% as well as in its tablets with a mean percentage recovery 99.47 ± 1.25%. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Safety of 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Safety of 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Comparative studies of synthesis of symmetric 2,6-di(benzofuran-2-yl)-4-phenylpyridine derivatives via pyrylium tetrafluoroborate salt and 1,5-dione derivatives was written by Kumar, D. B. Aruna;Desai, Nivedita R.;Krishnaswamy, G.;Sreenivasa, S.;Mahadevan, K. M.. And the article was included in Indian Journal of Chemistry in 2015.Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone This article mentions the following:

Two pathways for the synthesis of sym. 2,6-di(benzofuran-2-yl)-4-arylpyridines I (R¹ = H, Br; R² = Ph, 4-ClC₆H₄, 4-MeOC₆H₄, 4-O₂NC₆H₄) from the corresponding 5-R¹-substituted 2-acetylbenzofurans and aromatic aldehydes R²CHO were evaluated. In the method A, boron trifluoride etherate-assisted condensation of acetylbenzofurans with aldehydes gave the corresponding 4-aryl-2,6-bis(benzofuranyl)pyrylium tetrafluoroborates which were converted in the compounds I by ring opening/recyclization in the presence of ammonium acetate at room temperature In the method B, grinding the reactants under basic conditions in the minimal amount of MeCN afforded the corresponding 1,5-di(benzofuranyl)-3-arylpentane-1,5-diones which reacted with ammonium acetate in acetic acid under reflux to give the compounds I. The method B proceeded under mild reaction conditions in a shorter reaction time and generally provided higher product yields compared to the method A. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone).

1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Synthesis and antimicrobial activity of new heterocyclic compound containing 5-bromobenzofuran was written by Baaiu, Basma Saad;Abdelsalam, Mansour. And the article was included in Journal of Modern Chemistry & Chemical Technology in 2020.Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone This article mentions the following:

Several pyridine derivatives were synthesized via reaction of 2-acetyl 5-bromobenzofuran and 1,3-diphenyl-1 H-pyrazole-4-carbaldehyde gave chalcone which was exploited as a starting material. Structures of newly synthesized derivatives were confirmed by elemental anal., spectral data, chem. transformation and alternative synthetic route whenever possible. Also, the newly synthesized derivatives were screened towards some microorganism. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone).

1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Trypanocidal diamidines with four rings in one or two ring systems was written by Dann, Otto;Volz, Gerda;Demant, Ekke;Pfeifer, Wolfgang;Bergen, Gerhard;Fick, Helmut;Walkenhorst, Ekkehard. And the article was included in Justus Liebigs Annalen der Chemie in 1973.Reference of 38220-75-6 This article mentions the following:

The amidinobenzothienoindole I [R = C(:N+H2)NH2 Cl-] was prepared by reaction of 3-acetoxy-5-bromobenzo-[b]thiophene with 3-BrC6H4NHNH2 and converting the resulting bromide I (R = Br) via the nitrile I (R = CN). The hexahydrochrysene II [R = C(:N+H2)NH2Cl-, X = H2] was prepared starting from its dioxo analog II (R = H, X = O) by nitration via the dinitro compound II (R = NO2, X = O) and appropriate conversions. Similarly prepared was the hexadehydro analog of II. The benzofuranylindoles III [R = C(:N+H2)NH2Cl-, x = 5 or 6] were prepared by reaction of 2-acetyl-5-bromobenzofuran with y-BrC6H4NHNH2 (y = 3 or 4), cyclization of the resulting hydrazone, and conversion of R = Br into R = C(:N+H2)NH2Cl-. The naphthylbenzothiophene IV [R = C(:N+H2)NH2Cl-] was prepared by ring closure of 3-RC6H4SCH2COX1Br (R = Me, X1 = 2,6-naphthylene) via IV (R = CN). Similarly, the naphthothiophene V was prepared by ring closure of BrX1SCH2COC6H4Br-4. The bis(benzofuranyl)methane VI [Z = CH2, X = X1 = O, R = C(:N+H2)NH2C1-, R1 = H] was prepared by reaction of 2-(2-bromoacetyl)-5-bromobenzofuran with 5,2-Br(HO)C6H3CHO and reduction of the keto groups. Wittig reaction led to the analogs VI (Z = CH:CH, CH:CMe, CH2CH2, or CH2CHMe; X, X1 = O or S; R1 = H or Me). The trypanocidal properties of the diamidines are impaired due to the rigidity of the skeleton and its enlargement. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Reference of 38220-75-6).

1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Reference of 38220-75-6

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Dual-mode multicolored photonic crystal patterns enabled by ultraviolet-responsive core-shell colloidal spheres was written by Gao, Zewen;Huang, Chao;Yang, Dian;Zhang, Hanbing;Guo, Jinbao;Wei, Jie. And the article was included in Dyes and Pigments in 2018.Name: 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione This article mentions the following:

The authors developed a new kind of dual-mode multicolored photonic crystals (PCs), which could be used as a new type of dye, and achieved multicolored patterns. This kind of PCs can exhibit not only distinct structural colors due to Bragg’s law of diffraction but also nonstructural colors due to fluorescence. The authors used UV-responsive colloidal spheres synthesized by polymerization of semi-continuous emulsions to assemble the PCs. In this synthesis, the fluorescent precursors with carbamate groups were locally restricted to the shell of prepared spheres. UV irradiation can induce photo-decomposition of the carbamate groups in the fluorescent precursors, generating amino groups in the process. This process allowed the assembled PCs to exhibit fluorescence through treatment with fluorescamine. The authors prepared 2-dimensional (2D) multicolored photonic patterns of different sizes, with both reflection and fluorescence modes. These patterns were prepared either by vertical deposition under selective UV irradiation, or by spray coating. The authors fabricated 3-dimensional (3D) multicolored photonic patterns using 3D templates, as well as through spray coating. The results expand the concept of responsive PCs, and offer potential applications for multicolored photonic crystal patterns (PC patterns) in the field of optical storage, color displays, and anti-counterfeiting. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Name: 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Name: 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Conjugates of Immunoglobulin-Binding Protein and Gold Nanoparticle: Determination of Composition and Application in Immunochromatographic Analysis of Sulfonylamide was written by Sotnikov, D. V.;Barshevskaya, L. V.;Zherdev, A. V.;Dzantiev, B. B.. And the article was included in Applied Biochemistry and Microbiology in 2022.COA of Formula: C17H10O4 This article mentions the following:

A new method for determining the composition of protein-nanoparticle conjugates is proposed in this paper that uses fluorescamine as a fluorescent marker. This method allows obtaining high accuracy results and is characterized by minimal duration and laboriousness. Conjugates of gold nanoparticles with streptococcal protein G were characterized by composition and Ig-binding properties. The optimal concentrations of protein G and gold nanoparticles with an average diameter of 25 nm were found to be 8μg/mL and 2.5 nM (OD₅₂₀ = 5), resp. The obtained conjugates were used for the developed immunochromatog. anal. of the antibiotic sulfonylamide as a relevant contaminant that is controlled in food products. Indirect labeling of specific antibodies allowed using crude rabbit antiserum in the anal. The visual and instrumental detection limits of sulfonylamide were 100 ng/mL and 0.3 ng/mL, resp. The time of the assay was 10 min. The developed assay was tested for the characterization of honey samples. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9COA of Formula: C17H10O4).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.COA of Formula: C17H10O4

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

A novel spectrofluorimetric method for the determination of calcitonin in ampuls through derivatization with fluorescamine was written by Kocdan, Deniz;Basan, Hasan. And the article was included in Luminescence in 2013.Product Details of 38183-12-9 This article mentions the following:

In this study, a simple, sensitive, and selective spectrofluorimetric method was developed for the determination of salmon calcitonin (sCT) in ampuls. The method is based on the reaction between sCT and fluorescamine at pH 8.5 in borate buffer, resulting in a highly fluorescent derivative Fluorescence of derivatized sCT solutions was measured by setting the excitation and emission monochromators and slit widths to 390, 484, and 10 nm, resp. Several derivatization parameters were optimized. A calibration graph was constructed using standard solutions of the derivatized calcitonin in the range 0.5-6.0 μg/mL. Limit of detection and limit of quantification values were determined to be 0.124 and 0.372 μg/mL, resp. The proposed method was successfully applied for the determination of sCT in com. available ampuls. High recovery values (101.0-102.0%), and a low relative standard deviation (RSD %) value (5.3-5.4) proved the accuracy and precision of the proposed method. An isocratic reversed-phase high-performance liquid chromatog. (HPLC) method, as a reference, was also developed for the determination of sCT. A reversed-phase Nucleosil C₁₈ column (250 mm × 4.6 mm i.d., 10 μm particle size, 120 Å pore size) was used and the detector was set at 210 nm. Statistical comparison of the results of the 2 methods showed clearly that there was no significant difference between them. Copyright © 2012 John Wiley & Sons, Ltd. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Product Details of 38183-12-9).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.Product Details of 38183-12-9

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

PLGA protein nanocarriers with tailor-made fluorescence/MRI/PET imaging modalities was written by Zhang, Yajie;Garcia-Gabilondo, Miguel;Grayston, Alba;Feiner, Irene V. J.;Anton-Sales, Irene;Loiola, Rodrigo A.;Llop, Jordi;Ramos-Cabrer, Pedro;Barba, Ignasi;Garcia-Dorado, David;Gosselet, Fabien;Rosell, Anna;Roig, Anna. And the article was included in Nanoscale in 2020.Application of 38183-12-9 This article mentions the following:

Designing theranostic nanocarriers with high protein payload and multimodality tracking without cross interferences between the different imaging probes and the delicate protein cargo is challenging. Here, chem. modifications of poly(lactic-co-glycolic acid) (PLGA) to produce nanocapsules (NCs) that incorporate several imaging moieties are reported. The biocompatible and biodegradable PLGA-NCs can be endowed with a magnetic resonance imaging (MRI) reporter, two fluorescence imaging probes (blue/NIR) and a positron emission tomog. (PET) reporter. The modular integration of these imaging moieties into the shell of the NCs is successfully achieved without affecting the morphochem. properties of the nanocarrier or the protein loading capacity. In vivo biodistribution of the NCs is monitored by MRI, PET and NIRF and the results from different techniques are analyzed comparatively. The viabilities of two different human endothelial cells in vitro show no toxicity for NC concentration up to 100μg mL^-1. The morbidity of mice for 2 wk after systemic administration and the hepatic/pancreatic enzymes at the plasma level indicate their in vivo biosafety. In summary, the new theranostic PLGA nanoplatform presented here shows versatile in vitro/in vivo multimodal imaging capabilities, excellent biosafety and over 1 wt% protein loading. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Application of 38183-12-9).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Application of 38183-12-9

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem