Comparative studies of synthesis of symmetric 2,6-di(benzofuran-2-yl)-4-phenylpyridine derivatives via pyrylium tetrafluoroborate salt and 1,5-dione derivatives was written by Kumar, D. B. Aruna;Desai, Nivedita R.;Krishnaswamy, G.;Sreenivasa, S.;Mahadevan, K. M.. And the article was included in Indian Journal of Chemistry in 2015.Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone This article mentions the following:
Two pathways for the synthesis of sym. 2,6-di(benzofuran-2-yl)-4-arylpyridines I (R1 = H, Br; R2 = Ph, 4-ClC6H4, 4-MeOC6H4, 4-O2NC6H4) from the corresponding 5-R1-substituted 2-acetylbenzofurans and aromatic aldehydes R2CHO were evaluated. In the method A, boron trifluoride etherate-assisted condensation of acetylbenzofurans with aldehydes gave the corresponding 4-aryl-2,6-bis(benzofuranyl)pyrylium tetrafluoroborates which were converted in the compounds I by ring opening/recyclization in the presence of ammonium acetate at room temperature In the method B, grinding the reactants under basic conditions in the minimal amount of MeCN afforded the corresponding 1,5-di(benzofuranyl)-3-arylpentane-1,5-diones which reacted with ammonium acetate in acetic acid under reflux to give the compounds I. The method B proceeded under mild reaction conditions in a shorter reaction time and generally provided higher product yields compared to the method A. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone).
1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem