In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 125-20-2, name is Thymolphthalein, introducing its new discovery. name: Thymolphthalein
A specific fluorescent probe for zinc ion based on thymolphthalein and it’s application in living cells
Many diseases are connected with chemical substances, zinc ion is most important ion in chemical substances, because zinc ion (Zn2+) has been shown extensively involved in various physiological and pathological processes. In this work, thymolphthalein with good biocompatibility was introduced, the probe was constructed with interweaved benzimidazole and phenol from into the fluorophore system, hydroxyl and amino creating a multipoint binding pocket, which zinc can coordinate in a cooperative breaking Excited-State Intramolecular Proton Transfer, ESIPT. The fluorescence of this probe adding Zn2+ showed an obvious ?turn on? in a quick response within 5 s. In addition, the probe had a good selectivity for zinc ion over other analytes. Furthermore, we also studied the fluorescence imaging of probe in the presence of Zn2+ in living A549 cells.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 125-20-2, and how the biochemistry of the body works.name: Thymolphthalein
Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H4311O – PubChem