Palladium-Catalyzed Intramolecular C-H Arylation of Arenes Using Tosylates and Mesylates as Electrophiles was written by Nervig, Christine S.;Waller, Peter J.;Kalyani, Dipannita. And the article was included in Organic Letters in 2012.Application In Synthesis of Naphtho[2,1-b]benzofuran This article mentions the following:
This paper describes a method for the palladium catalyzed intramol. C-H arylation using tosylates and mesylates as electrophiles. E.g., in presence of Pd(OAc)2, 1,2-bis(dicyclohexylphosphino)ethane, Cs2CO3, and CsOPiv, C-H arylation of tosylate I gave 88% fused furan (II). The transformation is efficient for the synthesis of various heterocyclic motifs including furans, carbazoles, indoles, and lactams. Addnl., a protocol for the one-pot sequential tosylation/arylation of phenol derivatives is presented. In the experiment, the researchers used many compounds, for example, Naphtho[2,1-b]benzofuran (cas: 205-39-0Application In Synthesis of Naphtho[2,1-b]benzofuran).
Naphtho[2,1-b]benzofuran (cas: 205-39-0) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Application In Synthesis of Naphtho[2,1-b]benzofuran
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem