496-16-2, 2,3-Dihydrobenzo[b]furan is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(1) 7-Formyl-2,3-dihydrobenzofuran 108 ml of an n-butyllithium solution (2.1M) in hexane and 26.7 g (230 mmol) of tetramethylethylenediamine (TMEDA) are introduced into a 1 liter round-bottomed flask. The mixture is stirred at room temperature for 15 minutes and 23 g (190 mmol) of 2,3-dihydrobenzofuran are added. The mixture is stirred for 4 hours at 35 C., cooled to -78 C. and 13.9 g (190 mmol) of dimethylformamide are added. The temperature is allowed to return to 20 C., 500 ml of water are added and extraction is carried out with ethyl acetate (3*200 ml). The organic phases are combined, dried and concentrated under vacuum. The residue is purified by silica flash chromatography (elution: 5% ethyl acetate in petroleum ether). 9.85 g (Yield: 35%) of 7-formyl-2,3-dihydrobenzofuran are obtained–M.p.: 55 C.
496-16-2, As the paragraph descriping shows that 496-16-2 is playing an increasingly important role.
Reference£º
Patent; Synthelabo; US6063810; (2000); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem