81742-10-1, 3,6-Dichlorotrimellitic Anhydride is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
81742-10-1, 4-(naphth-2-yl)-2-fluoro-1,3-dihydroxybenzene 14 (760 mg, 2.988 mmol) obtained from Example 3, anhydrous 2,5-dichlorotrimellitic acid 23 (780 mg, 2.988 mmol, PE Applied Biosystems, Foster City, CA (AB) Part No. 361892), nitrobenzene (5 mL), and aluminum chloride in nitrobenzene (15 mL, 1 M, Aldrich Chemical) were mixed and the mixture was stirred at room temperature for 16 hours. The reaction mixture was added to ice water (100 mL) and was poured into a magnetically stirred mixture of ethyl acetate (100 mL), 10% HCl (100 mL) was added, and aluminum salt was dissolved. The organic layer was washed with water (100 mL ¡Á 2) and washed with brine (100 mL ¡Á 1), dried over sodium sulfate, filtered, and the solvent was removed. The product was obtained as an isomeric mixture. The product was purified by silica gel column chromatography (silica gel,10% methanol in dichloromethane mobile phase) to obtain the desired slow moving isomer 340 mg (22%) .
The synthetic route of 81742-10-1 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; APPLIED BIOSYSTEMS Ltd. LIABILITY COMPANY; BENSON, SCOTT CONRAD; MENCHEN, STEVEN MICHAEL; THEISEN, PETER DAVID; UPADHYA, KRISHNA GAJANAN; HAUSER, JOAN DALE; (37 pag.)JP2015/57478; (2015); A;,
Benzofuran – Wikipedia
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