Category: benzofurans

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Formula: C10H8O3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 41019-56-1, Name is Methyl benzofuran-4-carboxylate, molecular formula is C10H8O3

The present invention relates to compounds of formula (I) including any stereochemically isomeric form thereof, or pharmaceutically acceptable salts thereof, for the treatment of tuberculosis.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Formula: C10H8O3, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 41019-56-1

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H2799O – PubChem

Electric Literature of 805250-17-3, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 805250-17-3, Name is Methyl 2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate, molecular formula is C11H12O4. In a Article，once mentioned of 805250-17-3

The free fatty acid receptor 1 (FFA1 or GPR40) and peroxisome proliferator-activated receptor delta (PPARdelta) have attracted a lot of attention due to their role in promoting insulin secretion and sensibility, respectively, which are two major features of diabetes. Therefore, the dual FFA1/PPARdelta agonists would increase insulin secretion and sensibility by FFA1 and PPARdelta activation. In this study, we hybrid FFA1 agonist AM-4668 with PPARdelta agonist GW501516, leading to the identification of orally bioavailable dual agonist 32, which revealed high selectivity over other PPARs. Moreover, compound 32 exhibited good pharmacokinetic profiles with high plasma concentration, sustained half-life and low clearance in vivo. During the hypoglycemic test, a dual agonist 32 enhanced the tolerance of ob/ob mice for glucose loading in a dose-dependent manner. Our results suggest that dual FFA1/PPARdelta agonist could be a valuable therapy for type 2 diabetes.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 805250-17-3. In my other articles, you can also check out more blogs about 805250-17-3

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3561O – PubChem

Related Products of 72985-23-0, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 72985-23-0, 6-Methylisobenzofuran-1(3H)-one, introducing its new discovery.

Pesticidal compounds of formula (I) wherein R¹, R², R³ and R4 are independently selected from hydrogen, cyano, halogen, lower alkyl optionally substituted by halogen, lower alkoxy optionally substituted by halogen, lower alkenyl optionally substituted by halogen; amino and mono- or di-(lower alkyl) amino;, R6 is oxygen or sulphur;, R7, R8 and R¹0 are independently selected from hydrogen, halogen, cyano, lower alkyl optionally substituted by halogen, lower alkoxy optionally substituted by halogen, lower thioalkoxy optionally substituted by halo; and, R9 is lower alkyl substituted by halogen or lower alkenyl optionally substituted by halogen. The preparation of these compounds together with their use in combatting insect, acarine and nemotode pests is also described.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 72985-23-0. In my other articles, you can also check out more blogs about 72985-23-0

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1345O – PubChem

Reference of 24673-56-1, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 24673-56-1, 3-Methylbenzofuran-2-carboxylic acid, introducing its new discovery.

A cobalt-catalyzed decarboxylative cross-coupling reaction of (hetero)aryl carboxylic acids with benzothiazoles or benzoxazoles is reported. This represents a first example of metal-catalyzed decarboxylative C-H heteroarylation of benzo-fused heterocycles. The transformation provides a convenient route, with good yields and functional group tolerance, to various important arylheteroaryl and unsymmetrical biheteroaryl structural motifs.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Reference of 24673-56-1. In my other articles, you can also check out more blogs about 24673-56-1

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H2757O – PubChem

496-41-3, Name is Benzofuran-2-carboxylic acid, belongs to benzofurans compound, is a common compound. Formula: C9H6O3In an article, once mentioned the new application about 496-41-3.

The synthesis and antimicrobial activity of a new series of 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazole derivatives 3-12 were described. The in vitro antimicrobial activity of the compounds was determined against some Gram-positive, Gram-negative bacteria and fungi and their drug-resistant isolates in comparison with standard drugs. Antimicrobial results indicated that the synthesized compounds possessed a broad spectrum of activity with MIC values 500-15.625 mug/ml. In the series, the most active compound against Candida krusei and Candida albicans isolate is 8 with MIC value 31.25 mug/ml. However, it is one dilution less potent than the compared fluconazole. Some of the screened compounds exhibit significant activity, having MIC value as 31.25 mug/ml in Pseudomonas aeruginosa having same activity as Rifampicin. Furthermore, considering the worth of developing new antibacterial agents against drug-resistant P. aeruginosa the present study explores the structure-activity relationship analysis of 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles using 3D-common features pharmacophore hypotheses approach.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1721O – PubChem

Reference of 27404-31-5, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.27404-31-5, Name is 2-(Benzofuran-3-yl)ethanamine, molecular formula is C10H11NO. In a Article，once mentioned of 27404-31-5

An efficient and versatile synthesis of a polycyclic diazinic system starting from oxazine has been developed using a two-step Michael/retro Michael and cyclization sequence. The substrates were synthesized with good to high yields giving rapid access to molecular diversity.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1600O – PubChem

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. category: benzofuran, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 1563-38-8, name is 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol. In an article，Which mentioned a new discovery about 1563-38-8

The invention relates to the technical field of pharmaceuticals, and provides a substituted aryl tetracyclic antifungal compound and pharmaceutically acceptable salts. The substituted aryl tetracyclic antifungal compound is as shown in a structural formula of the description. The invention further provides a preparation method of the compound and an application of the compound in preparing antifungal medicaments.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H2324O – PubChem

Related Products of 496-41-3, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 496-41-3, Name is Benzofuran-2-carboxylic acid, molecular formula is C9H6O3. In a Article，once mentioned of 496-41-3

Coordination complexes of transition metal cations (CoII, NiII, CuII and ZnII) containing coumarilate and N,N?-diethylnicotinamide were synthesized. The structural characterization and thermal behaviour analysis of novel samples synthesized were conducted through elemental analysis, magnetic susceptibility, solid-state UV?Vis, direct and injection probe mass spectra, FTIR spectra, thermoanalytic TG-DTG/DTA and single crystal X-ray diffraction methods. The structural details of single crystals of [Co(dena)2(H2O)4](coum)2 (I) and [Cu(coum)2(dena)2(H2O)2] (III) complexes were resolved completely. Moreover, the results of analysis obtained for [Ni(coum)2(dena)2(H2O)2] (II) and [Zn(dena)2(H2O)4](coum)2 (IV) complexes were interpreted considering the samples with crystal structures defined and made assumptions about the structural details. It was determined that the complex of CoII metal cation has salt-type structure and the coordination number of metal is accomplished to six as the sum of 4 mol of water and also 2 mol of N,N?-diethylnicotinamide ligands in trans position located within the coordination sphere. It was observed that 2 mol of coumarilate anions are located outside the coordination sphere and have stabilized to the charge (2+) of metal. The CuII complex has totally molecular structure, and the coordination sphere of metal cation was 6 as the sum of 2 mol of water, 2 mol of N,N?-diethylnicotinamide and 2 mol of monoanionic monodentate coumarilate ligands. All ligands have been located in ?trans position. The geometry of both complex structures is distorted octahedral. It is assumed that the NiII complex structure is isostructural with CuII complex structure and also does ZnII complex with CoII structure. It was determined that the decomposition products obtained from thermal analysis are the oxides of related metal cations.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 496-41-3. In my other articles, you can also check out more blogs about 496-41-3

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1780O – PubChem

Related Products of 64169-67-1, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.64169-67-1, Name is 1-(4-Fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile, molecular formula is C15H10FNO. In a Patent，once mentioned of 64169-67-1

A process for producing the compound represented by the formula (II) which comprises reacting the compound represented by the formula (I) with oxalyl chloride; and a process for producing the compound represented by the formula (III) which comprises a step in which the compound represented by the formula (I) is reacted with oxalyl chloride to obtain the compound represented by the formula (II) and a step in which the compound represented by the formula (II) is reacted with a 3-dimethylaminopropyl halide.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 64169-67-1

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3877O – PubChem

Application of 496-41-3, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 496-41-3, Benzofuran-2-carboxylic acid, introducing its new discovery.

A method for the direct lithiation of terminal alkynes and heterocycles with subsequent carboxylation in a continuous flow format was developed. This method provides carboxylic acids at ambient conditions within less than five seconds with only little excess of the organometallic base and CO2. This journal is the Partner Organisations 2014.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 496-41-3. In my other articles, you can also check out more blogs about 496-41-3

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1927O – PubChem