Electric Literature of 805250-17-3, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 805250-17-3, Name is Methyl 2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate, molecular formula is C11H12O4. In a Article，once mentioned of 805250-17-3
The free fatty acid receptor 1 (FFA1 or GPR40) and peroxisome proliferator-activated receptor delta (PPARdelta) have attracted a lot of attention due to their role in promoting insulin secretion and sensibility, respectively, which are two major features of diabetes. Therefore, the dual FFA1/PPARdelta agonists would increase insulin secretion and sensibility by FFA1 and PPARdelta activation. In this study, we hybrid FFA1 agonist AM-4668 with PPARdelta agonist GW501516, leading to the identification of orally bioavailable dual agonist 32, which revealed high selectivity over other PPARs. Moreover, compound 32 exhibited good pharmacokinetic profiles with high plasma concentration, sustained half-life and low clearance in vivo. During the hypoglycemic test, a dual agonist 32 enhanced the tolerance of ob/ob mice for glucose loading in a dose-dependent manner. Our results suggest that dual FFA1/PPARdelta agonist could be a valuable therapy for type 2 diabetes.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 805250-17-3. In my other articles, you can also check out more blogs about 805250-17-3
Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3561O – PubChem