Category: benzofurans

Rapid determination of seven synthetic dyes in casual snacks based on packed-fibers solid-phase extraction coupled with HPLC-DAD was written by Han, Qing;Sun, Ying;Shen, Kangwei;Yan, Yan;Kang, Xuejun. And the article was included in Food Chemistry in 2021.Product Details of 16423-68-0 This article mentions the following:

Based on packed-fiber solid-phase extraction and HPLC-DAD, a simple anal. method for the determination of seven synthetic dyes has been successfully developed. Polystyrene/polypyrrole (PS/PPy) fibers were obtained via electro-spinning of polystyrene skeletal nanofibers, followed by the oxidation with FeCl3 to trigger the polymerization of pyrrole and the deposition of polypyrrole coatings on PS fibrous skeleton fibers. The relationship between the extraction performance of the fibers and the electrospinning process at different humidities was investigated based on morphol. study and BET surface area. In the extraction process, purification, concentration, and desorption could be accomplished in one step. The established method exhibited good sensitivity, selectivity, reproducibility, and good efficiency for synthetic dyes in casual snacks (preserved fruit, flavored yogurt, and fruity hard candy) samples. With optimal conditions, the LODs (S/N = 3) were 2.4 to 21.09 ng mL-1, and linearities were acceptable in liquid matrix and solid matrixes. The recoveries were 93.9-103.9%. In the experiment, the researchers used many compounds, for example, Sodium 2′,4′,5′,7′-tetraiodo-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-bis(olate) (cas: 16423-68-0Product Details of 16423-68-0).

Sodium 2′,4′,5′,7′-tetraiodo-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-bis(olate) (cas: 16423-68-0) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Product Details of 16423-68-0

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Synthesis of 2,2,7,7-tetramethyl-2,3,6,7-tetrahydrobenzo[1,2-b:6,5-b’]difuran derivatives was written by Ouyang, Yu-di;Wu, Dao-xin;Zang, Yang-ling;Luo, Xian-fu;Zhou, Yong;Mao, Chun-hui. And the article was included in Jingxi Huagong Zhongjianti in 2012.Application of 1563-38-8 This article mentions the following:

By using 2,2,7,7-tetramethyl-2,3,6,7-tetrahydrobenzo[1,2-b:6,5-b’]difuran, a byproduct formed during the preparation of 2,3-dihydro-2,2-dimethyl-7-benzofuranol, as the starting materials, three novel derivatives were synthesized via reactions of ring opening, Friedel-Craft and nucleophilic reaction. The target compounds were confirmed with ¹H NMR and MS. In the experiment, the researchers used many compounds, for example, 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8Application of 1563-38-8).

2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Application of 1563-38-8

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Synthesis of crystal violet lactone with urea technology was written by Tan, Tao;Bao, Chuanping;Ding, Yigang;Ding, Xiaojuan;Hu, Xiong. And the article was included in Yingyong Huagong in 2007.Recommanded Product: 1552-42-7 This article mentions the following:

LCVL was prepared by heating a certain ratio of urea, p-dimethylaminobenzaldehyde and N,N-dimethylaniline mixed and refluxed in the hydrochloric acid and under the protection of nitrogen at about 80° for 0.5 h, then reacted 5.5 h in the presence of m-dimethylaminobenzoic acid at about 93°C with 65% yield of LCVL. With potassium ferricyanide used as catalyst, LCVL dissolved in sodium hydroxide was oxidized to CVL by inpouring the air for 18 h. The yield of CVL was 90.50%. In the experiment, the researchers used many compounds, for example, Crystal violet lactone (cas: 1552-42-7Recommanded Product: 1552-42-7).

Crystal violet lactone (cas: 1552-42-7) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Recommanded Product: 1552-42-7

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Fraxinellone alleviates kidney fibrosis by inhibiting CUG-binding protein 1-mediated fibroblast activation was written by Zheng, Bingfeng;Yuan, Manman;Wang, Shenglan;Tan, Yang;Xu, Yizhu;Ye, Jing;Gao, Yanjie;Sun, Xueqing;Wang, Tianyi;Kong, Lingdong;Wu, Xingxin;Xu, Qiang. And the article was included in Toxicology and Applied Pharmacology in 2021.Formula: C14H16O3 This article mentions the following:

Chronic Kidney Disease (CKD) is a serious threat to human health. In addition, kidney fibrosis is a key pathogenic intermediate for the progression of CDK. Moreover, excessive activation of fibroblasts is key to the development of kidney fibrosis and this process is difficult to control. Notably, fraxinellone is a natural compound isolated from Dictamnus dasycarpus and has a variety of pharmacol. activities, including hepatoprotective, anti-inflammatory and anti-cancer effects. However, the effect of fraxinellone on kidney fibrosis is largely unknown. The present study showed that fraxinellone could alleviate folic acid-induced kidney fibrosis in mice in a dose dependent manner. Addnl., the results revealed that fraxinellone could effectively down-regulate the expression of CUGBP1, which was highly up-regulated in human and murine fibrotic renal tissues. Furthermore, expression of CUGBP1 was selectively induced by the Transforming Growth Factor-beta (TGF-β) through p38 and JNK signaling in kidney fibroblasts. On the other hand, downregulating the expression of CUGBP1 significantly inhibited the activation of kidney fibroblasts. In conclusion, these findings demonstrated that fraxinellone might be a new drug candidate and CUGBP1 could be a promising target for the treatment of kidney fibrosis. In the experiment, the researchers used many compounds, for example, (3R,3aR)-3-(Furan-3-yl)-3a,7-dimethyl-3a,4,5,6-tetrahydroisobenzofuran-1(3H)-one (cas: 28808-62-0Formula: C14H16O3).

(3R,3aR)-3-(Furan-3-yl)-3a,7-dimethyl-3a,4,5,6-tetrahydroisobenzofuran-1(3H)-one (cas: 28808-62-0) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Formula: C14H16O3

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Plasma CXCL9 and CXCL10 at allograft injury predict chronic lung allograft dysfunction was written by Shino, Michael Y.;Todd, Jamie L.;Neely, Megan L.;Kirchner, Jerry;Frankel, Courtney W.;Snyder, Laurie D.;Pavlisko, Elizabeth N.;Fishbein, Gregory A.;Schaenman, Joanna M.;Mason, Kristen;Kesler, Karen;Martinu, Tereza;Singer, Lianne G.;Tsuang, Wayne;Budev, Marie;Shah, Pali D.;Reynolds, John M.;Williams, Nikki;Robien, Mark A.;Palmer, Scott M.;Weigt, S. Sam;Belperio, John A.. And the article was included in American Journal of Transplantation in 2022.Formula: C17H20O6 This article mentions the following:

Histopathol. lung allograft injuries are putative harbingers for chronic lung allograft dysfunction (CLAD). However, the mechanisms responsible are not well understood. CXCL9 and CXCL10 are potent chemoattractants of mononuclear cells and potential propagators of allograft injury. We hypothesized that these chemokines would be quantifiable in plasma, and would associate with subsequent CLAD development. In this prospective multicenter study, we evaluated 721 plasma samples for CXCL9/CXCL10 levels from 184 participants at the time of transbronchial biopsies during their first-year post-transplantation. We determined the association between plasma chemokines, histopathol. injury, and CLAD risk using Cox proportional hazards models. We also evaluated CXCL9/CXCL10 levels in bronchoalveolar lavage (BAL) fluid and compared plasma to BAL with respect to CLAD risk. Plasma CXCL9/CXCL10 levels were elevated during the injury patterns associated with CLAD, acute rejection, and acute lung injury, with a dose-response relationship between chemokine levels and CLAD risk. Importantly, there were strong interactions between injury and plasma CXCL9/CXCL10, where histopathol. injury associated with CLAD only in the presence of elevated plasma chemokines. We observed similar associations and interactions with BAL CXCL9/CXCL10 levels. Elevated plasma CXCL9/CXCL10 during allograft injury may contribute to CLAD pathogenesis and has potential as a minimally invasive immune monitoring biomarker. In the experiment, the researchers used many compounds, for example, (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid (cas: 24280-93-1Formula: C17H20O6).

(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid (cas: 24280-93-1) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.Formula: C17H20O6

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Metabolomics reveals inosine 5′-monophosphate is increased during mice adipocyte browning was written by Takahashi, Haruya;Tokura, Motohiro;Kawarasaki, Satoko;Nagai, Hiroyuki;Iwase, Mari;Nishitani, Kento;Okaze, Haruka;Mohri, Shinsuke;Ito, Tetsuro;Ara, Takeshi;Jheng, Huei-Fen;Nomura, Wataru;Kawada, Teruo;Inoue, Kazuo;Goto, Tsuyoshi. And the article was included in Journal of Biological Chemistry in 2022.Related Products of 24280-93-1 This article mentions the following:

Adipocyte browning is one of the potential strategies for the prevention of obesity-related metabolic syndromes, but it is a complex process. Although previous studies make it increasingly clear that several transcription factors and enzymes are essential to induce browning, it is unclear what dynamic and metabolic changes occur in induction of browning. Here, we analyzed the effect of a beta-adrenergic receptor agonist (CL316243, accelerator of browning) on metabolic change in mice adipose tissue and plasma using metabolome anal. and speculated that browning is regulated partly by IMP (IMP) metabolism To test this hypothesis, we investigated whether Ucp-1, a functional marker of browning, mRNA expression is influenced by IMP metabolism using immortalized adipocytes. Our study showed that mycophenolic acid, an IMP dehydrogenase inhibitor, increases the mRNA expression of Ucp-1 in immortalized adipocytes. Furthermore, we performed a single administration of mycophenolate mofetil, a prodrug of mycophenolic acid, to mice and demonstrated that mycophenolate mofetil induces adipocyte browning and miniaturization of adipocyte size, leading to adipose tissue weight loss. These findings showed that IMP metabolism has a significant effect on adipocyte browning, suggesting that the regulator of IMP metabolism has the potential to prevent obesity. In the experiment, the researchers used many compounds, for example, (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid (cas: 24280-93-1Related Products of 24280-93-1).

(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid (cas: 24280-93-1) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Related Products of 24280-93-1

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Additive manufactured macroporous chambers facilitate large volume soft tissue regeneration from adipose-derived extracellular matrix was written by Zhang, Guo;Ci, Hai;Ma, Chenggong;Li, Zhipeng;Jiang, Wenbin;Chen, Lifeng;Wang, Zhenxing;Zhou, Muran;Sun, Jiaming. And the article was included in Acta Biomaterialia in 2022.HPLC of Formula: 1461-15-0 This article mentions the following:

Breast tissue engineering is a promising alternative intervention for breast reconstruction. Due to their low immunogenicity and well-preserved adipogenic microenvironment, decellularized adipose tissue (DAT) can potentially regenerate adipose tissue in vivo. However, the volume of adipose tissue regenerated from DAT can hardly satisfy the demand for breast reconstruction. Tissue engineering chamber (TEC) is an effective technique for generation of large adipose tissue volumes However, TEC applications necessitate reoperation to remove non-degradable plastic chambers and harvest autologous tissue flaps, which prolongs the operation time and causes potential damage to donor sites. We improved the TEC strategy by combining bioresorbable polycaprolactone (PCL) chambers and decellularized adipose tissues (DAT). A miniaturized porous PCL chamber was fabricated based on scaling differences between human and rabbit chests, and basic fibroblast growth factor (bFGF)-loaded DAT successfully prepared In rabbit models, a highly vascularized adipose tissue that nearly filled up the PCL chamber (5 mL) was generated de novo from 0.5 mL bFGF-loaded DAT. The newly formed tissue had significantly high expressions of adipogenic genes, compared to the endogenous adipose tissue. The concept described here can be exploited for breast tissue engineering. Decellularized adipose tissue (DAT), which provides infiltrated cells adipogenic microenvironment, can potentially regenerate adipose tissue in vivo. Nevertheless, the volume of regenerated adipose tissue is insufficient to repair large sized tissue defect. Tissue engineering chamber (TEC) could provide a protective space for in situ regeneration of large volume tissue. Herein, a new strategy by combining biodegradable polycaprolactone chambers and basic fibroblast growth factor-loaded decellularized adipose tissue is proposed. In rabbit model, newly formed adipose tissue regenerated from DAT successfully filled the dome shaped chamber with ten folds higher volume than DAT, which is proportionally similar to women breast. This work highlighted the importance of adipogenic microenvironment and protective space for adipose tissue regeneration. In the experiment, the researchers used many compounds, for example, 2,2′,2”,2”’-(((3′,6′-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-2′,7′-diyl)bis(methylene))bis(azanetriyl))tetraacetic acid (cas: 1461-15-0HPLC of Formula: 1461-15-0).

2,2′,2”,2”’-(((3′,6′-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-2′,7′-diyl)bis(methylene))bis(azanetriyl))tetraacetic acid (cas: 1461-15-0) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.HPLC of Formula: 1461-15-0

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Enhanced photo-catalytic efficiency through dual-functional ZIF based materials: Fabrication and application as a degradation of organic dyes was written by Li, Xuelian;Raza, Saleem;Liu, Changkun. And the article was included in Journal of the Taiwan Institute of Chemical Engineers in 2021.Recommanded Product: Sodium 2′,4′,5′,7′-tetraiodo-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-bis(olate) This article mentions the following:

Photocatalytic technol. is considered the most promising green technol. for the degradation and removal of organic pollutants. In this paper, an innovative multifunctional photocatalytic material has been successfully prepared The zeolitic-imidazolate-framework-67 (ZIF-67) was first synthesized by an easy and green approach. Then, a polydopamine (PDA) mid-layer was incorporated on its surface via dopamine self-polymerization, which not only serves as a stable linking agent, but also increases the amount of visible light captured and reduces the recombination of photogenerated electron-hole pairs. After the hydrolysis and hydrothermal process of tetra-Bu orthotitanate, the TiO₂ nanoparticles were uniformly grafted on the surface, and finally, the hollow ZIF-67@PDA@TiO₂ was successfully obtained. The prepared H-ZIF-67@PDA@TiO₂ photocatalyst was characterized by various techniques, and further used for the photo degradation of a variety of dyes in wastewater in the presence of visible light. A degradation rate of almost 100% was achieved for Acid Fuchsin and Congo Red within 40 min, followed by Erythrosine B and Rose Bengal with a 99% degradation rate within 150 min. Moreover, the ZIF-67-based photocatalyst exhibited high stability and recyclability and maintained an excellent photocatalytic performance during continued cycling. Furthermore, the superoxide radical (•O^–₂) and the hydroxyl radical (•OH) were the primary and secondary reactive species during photodegradation Overall, the excellent performance of this simple photocatalyst was clearly demonstrated, and its numerous advantages, such as low energy consumption, low cost, non-toxicity, and environmental friendliness, showing promising potential for its practical implementation. In the experiment, the researchers used many compounds, for example, Sodium 2′,4′,5′,7′-tetraiodo-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-bis(olate) (cas: 16423-68-0Recommanded Product: Sodium 2′,4′,5′,7′-tetraiodo-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-bis(olate)).

Sodium 2′,4′,5′,7′-tetraiodo-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-bis(olate) (cas: 16423-68-0) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Recommanded Product: Sodium 2′,4′,5′,7′-tetraiodo-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-bis(olate)

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Establishment of HPLC fingerprint of Sophora tonkinensis var. polyphylla from Guangxi and comparison of concordance with HPLC fingerprint of S. tonkinensis was written by Liu, Ji-cheng;Lu, Sen-hua;Xie, Wei;Lu, Wen-jie. And the article was included in Zhongguo Shiyan Fangjixue Zazhi in 2014.Formula: C22H22O10 This article mentions the following:

Objective: To establish the HLPC fingerprint method of Sophora tonkinensis var. polyphylla, to provide the reference for scientific evaluation and quality control of S. tonkinensis var. polyphylla herb, and to provide the reference data for the homol. study of Sophora tonkinensis var. polyphylla and S. tonkinensis through comparing the fingerprints. Method: An HPLC method was used. An Agilent Eclipse XDB-C₁₈ (4.6 mm × 250 mm, 5 μm) column was adopted, and the mobile phase consisted of acetonitrile and 0.05 mol·L^-1 potassium dihydrogen phosphate solution (adjusted with triethylamine pH 6.4) with a gradient elution. The flow rate was 1.0 mL·min^-1, the column temperature was 30°C, and the detection wavelength was 215 nm. A ‘Chromatog. Fingerprint Evaluation System 2004A Edition’ software was used for data processing. Result: The establishment fingerprint of S. tonkinensis var. polyphylla had 14 common peaks and 7 peaks of them were identified using the reference retention time and UV-DAD detector extracted spectra dual qual. indicators. Most of the compare similarities of fingerprints of each batch herb were above 0.90, in line with the requirements of fingerprint technol. research. Compared with the fingerprint of S. tonkinensis var. polyphylla and S. tonkinensis, the similarity was above 0.90. Conclusion: The precision, stability and reproducibility of the established method were good. The method could be effectively used for the quality control of S. tonkinensis var. polyphylla herb and provide a scientific basis for the development and use of the herb. It could be inferred that S. tonkinensis var. polyphylla and S. tonkinensis had similar ingredients and close relationships from the comparison study of their fingerprints. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-2-(((6aR,12aR)-6a,12a-Dihydro-6H-[1,3]dioxolo[4′,5′:5,6]benzofuro[3,2-c]chromen-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 6807-83-6Formula: C22H22O10).

(2S,3R,4S,5S,6R)-2-(((6aR,12aR)-6a,12a-Dihydro-6H-[1,3]dioxolo[4′,5′:5,6]benzofuro[3,2-c]chromen-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 6807-83-6) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Formula: C22H22O10

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Selective Enzymatic Degradation of Self-Assembled Particles from Amphiphilic Block Copolymers Obtained by the Combination of N-Carboxyanhydride and Nitroxide-Mediated Polymerization was written by Habraken, Gijs J. M.;Peeters, Marloes;Thornton, Paul D.;Koning, Cor E.;Heise, Andreas. And the article was included in Biomacromolecules in 2011.Quality Control of 2,5-Dioxopyrrolidin-1-yl 3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-carboxylate This article mentions the following:

Combining controlled radical polymerizations and a controlled polypeptide synthetic technique, such as N-carboxyanhydride (NCA) ring-opening polymerization, enables the generation of well-defined block copolymers to be easily accessible. Here we combine NCA polymerization with the nitroxide-mediated radical polymerization of poly(Bu acrylate) (PBA) and polystyrene (PS), using a TIPNO and SG1-based bifunctional initiator to create a hybrid block copolymer. The polypeptide block consists of (block) copolymers of poly(L-glutamic acid) embedded with various quantities of L-alanine. The formed superstructures (vesicles and micelles) of the block copolymers possessed varying degrees of enzyme responsiveness when exposed to elastase and thermolysin, resulting in controlled enzymic degradation dictated by the polypeptide composition The PBA containing block copolymers possessing 50% L-alanine in the polypeptide block showed a high degradation response compared to polymers containing lower L-alanine quantities. The particles stabilized by copolypeptides with L-alanine near the hydrophobic block showed full degradation within 4 days. Particles containing polystyrene blocks revealed no appreciable degradation under the same conditions, highlighting the specificity of the system and the importance of synthetic polymer selection. However, when the degradation temperature was increased to 70 °C, degradation could be achieved due to the higher block copolymer exchange between the particle and the solution A number of novel biohybrid structures are disclosed that show promise as enzyme-responsive materials with potential use as payload release vehicles, following their controlled degradation by specific, target, enzymes. In the experiment, the researchers used many compounds, for example, 2,5-Dioxopyrrolidin-1-yl 3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-carboxylate (cas: 92557-80-7Quality Control of 2,5-Dioxopyrrolidin-1-yl 3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-carboxylate).

2,5-Dioxopyrrolidin-1-yl 3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-carboxylate (cas: 92557-80-7) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.Quality Control of 2,5-Dioxopyrrolidin-1-yl 3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-carboxylate

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem