Category: benzofurans

143878-29-9, Name is Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate, belongs to benzofurans compound, is a common compound. COA of Formula: C12H12ClNO4In an article, once mentioned the new application about 143878-29-9.

The invention discloses a process for the alkylation of active methylene compounds. The method comprises the following steps: step A: lively methano-compound will be added to the inorganic alkali -1st polar organic solvent in the mixed system, to be reaction mixture formed; step B:in to be reaction mixture by adding the alkylating agent, the filtrate filtered to get after the reaction, to remove the solvent in the filtrate alkylation chirpy methano-compound obtained. The above-mentioned method, active methylene compounds with inorganic alkali as proton of the reagent composition, not only can ensure in its lively methano-compound alpha-hydrogen getting rid of effects, but also can the vivid methano-compound in the alkylation reaction carried out under relatively mild conditions, to improve the safety of the reaction. At the same time, relatively low price of inorganic base, the alkylation reaction of the production cost is reduced. (by machine translation)

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H4059O – PubChem

Related Products of 1199-07-1, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 1199-07-1, 3-Methylbenzofuran-2-carbaldehyde, introducing its new discovery.

The first example of PdII-catalyzed gamma-C(sp3)?H functionalization of aliphatic and benzoheteroaryl aldehydes has been developed using a transient ligand and an external ligand, concurrently. A wide array of gamma-arylated aldehydes were readily accessed without preinstalling internal directing groups. The catalytic mechanism was studied by performing deuterium-labelling experiments, which indicated that the gamma-C(sp3)?H bond cleavage is the rate-limiting step during the reaction process. This reaction could be performed on a gram scale, and also demonstrated its potential application in the synthesis of new mechanofluorochromic materials with blue-shifted mechanochromic properties.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 1199-07-1. In my other articles, you can also check out more blogs about 1199-07-1

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1570O – PubChem

Chemistry is traditionally divided into organic and inorganic chemistry. Safety of 5-Methoxybenzofuran-3(2H)-one, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 39581-55-0

3-Oxo-2,3-dihydrobenzo[b]furans, -thiophenes and -selenophenes 1a-c afforded the bromo-aldehydes 2 under Vilsmeier-Haack-Arnold conditions. Palladium-catalysed aryl-aryl coupling of 2 with o-formyl-phenylboronic acid allowed the formation of dialdehydes 3 which underwent McMurry cyclisation or pinacol condensation to yield polycyclic aromatic derivatives 4 or the dihydroxylated compounds 5.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H2236O – PubChem

4265-25-2, Name is 2-Methylbenzofuran, belongs to benzofurans compound, is a common compound. Recommanded Product: 4265-25-2In an article, once mentioned the new application about 4265-25-2.

The invention relates to a benzofuran compound of the preparation method. The preparation method comprises the following steps: the furyl compound, acetic acid and Lewis acid catalyst in the reaction container, for 80 – 160 C reaction under the condition 0.5 – 24 h, separation and purification, to get the benzofuran compound. The present invention provides a preparation method of the furan compound to the raw materials of reaction, to acetic acid aqueous solution as the solvent, to Lewis acid as catalyst, the mild reaction temperature (80 – 160 C) lower, through the one-step reaction for directly obtaining a benzofuran compound. The present invention provides the preparation method based on the raw material furan compound of structure and functional group, the synthesis of the corresponding structure and functional group of the benzofuran compound, the raw material components is simple, convenient operation of technique; wherein in order to furan synthetic benzofuran in the process, the resulting benzofuran selectivity as high as 99%, and has industrial application prospect. (by machine translation)

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Benzofuran – Wikipedia,
Benzofuran | C8H10O – PubChem

Chemistry is traditionally divided into organic and inorganic chemistry. Recommanded Product: 4265-25-2, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 4265-25-2

A new approach for the cyclopenta[b]annulation of heteroarenes through metal-free and directing-group-free gamma?[C(sp3)?H] functionalization and intramolecular hydroalkylation of ynones has been developed. In an unprecedented event, nucleophilic addition of an organophosphine to the designed ynones triggers gamma?[C(sp3)?H] functionalization, leading to the formation of heteroaryl-based ortho-quinodimethane (oQDM) intermediates that undergo carbocyclization to provide cyclopentannulated heteroarenes in good yields and excellent stereoselectivities. Deuterium-labeling experiments substantiated the proposed reaction mechanism as well as the speculated epimerization.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H250O – PubChem

Related Products of 496-41-3, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 496-41-3, Benzofuran-2-carboxylic acid, introducing its new discovery.

The present invention discloses a method for the preparation of carboxylic acid comprising contacting beta-ketosulfone of Formula (I) with nitrous acid.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 496-41-3. In my other articles, you can also check out more blogs about 496-41-3

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1624O – PubChem

Chemistry is traditionally divided into organic and inorganic chemistry. Formula: C8H7NO2, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 57319-65-0

A novel visible-light photocatalytic difluoromethylselenolation of aryl amines via in situ generation of aryldiazonium salts was achieved using Se-(difluoromethyl) 4-methylbenzenesulfonoselenoate, which was synthesized for the first time. The reagent is readily accessible and shelf-stable. The metal-free reaction conditions and the broad substrate scope provide a green protocol for the efficient and rapid introduction of the difluoromethylselenylether group.

If you are interested in 57319-65-0, you can contact me at any time and look forward to more communication. Formula: C8H7NO2

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1397O – PubChem

Synthetic Route of 189035-22-1, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.189035-22-1, Name is 6-Bromo-2,3-dihydrobenzofuran, molecular formula is C8H7BrO. In a Patent，once mentioned of 189035-22-1

Provided is a compound having an AMPA receptor function enhancing action, and useful as a prophylactic or therapeutic drug for depression, schizophrenia, Alzheimer’s disease, attention deficit hyperactivity disorder (ADHD) and the like. The compound represented by formula (I): wherein each symbol is as defined in the DESCRIPTION, or a salt thereof has an AMPA receptor function enhancing action, and is useful as a prophylactic or therapeutic frug for depression, schizophrenia, Alzheimer’s disease or attention deficit hyperactivity disorder (ADHD) and the like.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 189035-22-1

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3407O – PubChem

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 64175-51-5, name is 2-(Benzofuran-3-yl)acetic acid, introducing its new discovery. Safety of 2-(Benzofuran-3-yl)acetic acid

The electrochemical reduction of a series of 2-haloaryl ethers containing allyl and propargyl groups under CO2 allows the synthesis of benzofuranacetic acid derivatives. This novel intramolecular cyclization- carboxylation reaction is carried out in single-compartment cells and is catalyzed by [Ni(cyclam)Br2].

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H2675O – PubChem

Reference of 4265-25-2, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 4265-25-2, molcular formula is C9H8O, introducing its new discovery.

The direct alkynylation of benzofurans was achieved for the first time using the hypervalent iodine reagent 1-[(triiso-propylsilyl)ethynyl]-1,2- benziodoxol-3(1H)-one (TIPS-EBX) based on the cooperative effect between a gold catalyst and a zinc Lewis acid. High selectivity was observed for C2-alkynylation of benzofurans substituted with alkyl, aryl, halogen and ether groups. The reaction was also successful in the case of the more complex drug 8-methoxypsoralen (8-MOP).

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 4265-25-2 is helpful to your research. Reference of 4265-25-2

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H179O – PubChem