143878-29-9, Name is Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate, belongs to benzofurans compound, is a common compound. COA of Formula: C12H12ClNO4In an article, once mentioned the new application about 143878-29-9.
The invention discloses a process for the alkylation of active methylene compounds. The method comprises the following steps: step A: lively methano-compound will be added to the inorganic alkali -1st polar organic solvent in the mixed system, to be reaction mixture formed; step B:in to be reaction mixture by adding the alkylating agent, the filtrate filtered to get after the reaction, to remove the solvent in the filtrate alkylation chirpy methano-compound obtained. The above-mentioned method, active methylene compounds with inorganic alkali as proton of the reagent composition, not only can ensure in its lively methano-compound alpha-hydrogen getting rid of effects, but also can the vivid methano-compound in the alkylation reaction carried out under relatively mild conditions, to improve the safety of the reaction. At the same time, relatively low price of inorganic base, the alkylation reaction of the production cost is reduced. (by machine translation)
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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H4059O – PubChem