Category: 61090-37-7

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Application In Synthesis of 2,3-Dihydrobenzofuran-4-amine, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 61090-37-7, name is 2,3-Dihydrobenzofuran-4-amine. In an article£¬Which mentioned a new discovery about 61090-37-7

Synthetic method of ramelteamine (by machine translation)

The invention discloses a synthetic method of ramelteon. To the method, an aryl ammonia 4 – compound is converted into an aryl iodide compound under the action of a palladium catalyst, an inorganic base, a phosphine ligand, a norbornene derivative and an additive under the action of a palladium catalyst, an inorganic base, a phosphine ligand, a norbornene derivative and an additive 26%. Compared with the prior art, the synthetic method disclosed by the invention is capable of obtaining 4 – the target molecule rapamycin only through three steps from the commercially available commercially available compound Uamino-2, 3-dihydrobenzofuran, the synthesis steps are greatly shortened compared with other process routes, the steps are few, and the safety is high. (by machine translation)

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 61090-37-7, help many people in the next few years.Application In Synthesis of 2,3-Dihydrobenzofuran-4-amine

Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H477O – PubChem

61090-37-7, One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time.In a article, authors is Marburg, S., mentioned the application of 61090-37-7, Name is 2,3-Dihydrobenzofuran-4-amine, molecular formula is C8H9NO

A Short Efficient Synthesis of 4-Amino-2,3-dihydrobenzofuran

A new, practical synthesis of 4-amino-2,3-dihydrobenzofuran is described.Chlorination and a Sandmeyer reaction of the title compound are also reported.

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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H482O – PubChem

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 61090-37-7, In a patent£¬Which mentioned a new discovery about 61090-37-7

BENZOTHIAZOLE DERIVATIVES AS DYRK1 INHIBITORS

The present invention relates to compounds of Formula (I), which are DYRK1A and/or DYRK1B inhibitors,and their use in the treatment of neurodegenerative disorders such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), metabolic disorders such as Metabolic Syndrome or diabetes mellitus, and cancer.

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, 61090-37-7, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 61090-37-7

Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H476O – PubChem

61090-37-7, 2,3-Dihydrobenzofuran-4-amine is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of 2,3-dihydro-4-benzofuranamine (72.3 g, 0.54 mol), hydroxylamine hydrochloride (131.3 g, 1.8 mol), conc. hydrochloric acid (45 mL) and water (1265 mL) was stirred at room temperature for 30 min. A solution of chloral hydrate (98.2 g, 0.59 mol) in water (1265 mL) was added followed by solid sodium sulphate (767 g, 5.4 mol) and the reaction was heated to reflux for 1 h. The reaction was cooled to room temperature and the solid was collected by filtration. The solid was suspended in ethyl acetate (250 mL) and water (250 mL) and then extracted with ethyl acetate (3*250 mL). The organic extracts were combined, dried (magnesium sulphate) and concentrated in vacuo to afford the title compound (41 g, 38%) as a pale brown solid; NMR (400 MHz, DMSO-d6) deltaH 3.12 (2H, t, J 9.0 Hz), 4.52 (2H, t, J 8.5 Hz), 6.58 (1H, d, J 8.0 Hz), 7.06 (1H, t, J 8.5 Hz), 7.14 (1H, d, J 8.5 Hz), 7.7 (1H, s), 9.66 (1H, br s), 12.19 (1H, br s); IR numax (Nujol)/cm-1 3389, 3160, 2923, 1661, 1620, 1607, 1540, 1453, 1238, 1060, 1029, 982 and 780., 61090-37-7

The synthetic route of 61090-37-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; VERNALIS RESEARCH LIMITED; US2005/187282; (2005); A1;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.61090-37-7,2,3-Dihydrobenzofuran-4-amine,as a common compound, the synthetic route is as follows.

61090-37-7, Hydrochloric acid (9.0 g) was added dropwise to a solution of 2,3-dihydrobenzofuran-4-amine (16.3 mmol) and acetic acid (9.0 g) in acetonitrile (200 mL) at 0 C. A solution of sodium nitrite (22.0 mmol) in water (2 mL) was subsequently added and the mixture was maintained for 30 min at 0 C.Sulfur dioxide gas was passed through the reaction mixture for 2 h whereupon a solution of copper(II) chloride dihydrate (20.0 mmol) in water (3 mL) was added. Sulfur dioxide gas was passed through the reaction mixture for an additional 2 h. The reaction mixture was allowed to warm to rt and was maintained for 16 h. The reaction mixture was diluted with ice water (200 mL) and the resulting mixture was extracted with ethyl acetate (300 mL). The organic layer was washed with water (200 mL), dried (sodium sulfate), and concentrated. The residue was purified by Flash chromatography (1/70 ethyl acetate/petroleum ether) to provide 2,3-dihydrobenzofuran-4-sulfonyl chloride in 40% yield as a yellow solid. Data: 1H NMR (CDCl3) delta 7.40 (d, 1H), 7.30 (d, 1H), 7.10 (d, 1H), 4.70 (m, 2H), 3.60 (m, 2H). LC/MS (ES) m/z 283 [M+C5H11N2-C1+H]+.

As the paragraph descriping shows that 61090-37-7 is playing an increasingly important role.

Reference£º
Patent; MEMORY PHARMACEUTICALS CORPORATION; WO2009/23844; (2009); A2;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem

61090-37-7,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.61090-37-7,2,3-Dihydrobenzofuran-4-amine,as a common compound, the synthetic route is as follows.

Dimethyl acetylene DICARBOXYLATE A3 (0.16 mL, 1.33 MMOL) was added to solution of aniline H5 (0. 18 g, 1.33 MMOL) in MeOH (3.0 mL) at R. T. The solution was heated at reflux for 3 h., cooled to R. T. and a saturated NAZI solution was added. The mixture was extracted with EtOAc (3x) and the combined organic layers were then dried, filtered and concentrated followed by purification by flash column chromatography (9: 1 to 1 : 1 hex : EtOAc) to afford the desired olefin H6 (0.29 g, 78%).

As the paragraph descriping shows that 61090-37-7 is playing an increasingly important role.

Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH & CO KG; WO2004/103996; (2004); A1;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem