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The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I): wherein R1, R2, R5, Q, G, Ar, m, and n are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

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Benzofuran – Wikipedia,
Benzofuran | C8H458O – PubChem

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The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I): wherein R1, R2, Ar, m and n are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

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HEPATITIS C INHIBITOR COMPOUNDS

Compounds of formula (I): wherein B, X, R3, L0, L1, L2, R2, R1 and RC are defined herein. The compounds are useful as inhibitors of HCV NS3 protease for the treatment of hepatitis C viral infection.

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Benzofuran – Wikipedia,
Benzofuran | C8H468O – PubChem

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A Short Efficient Synthesis of 4-Amino-2,3-dihydrobenzofuran

A new, practical synthesis of 4-amino-2,3-dihydrobenzofuran is described.Chlorination and a Sandmeyer reaction of the title compound are also reported.

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4′-AMINO CYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY

The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I): formula (I) wherein Cy is selected from formula (Il) and wherein R1, R2, R3, Q, G, Ar, m, n and p are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

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Benzofuran – Wikipedia,
Benzofuran | C8H475O – PubChem

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Tricyclic furo-quinazolinones

Anti-inflammatories and analgesics of the formula SPC1 Wherein X y is –OCH2 CH2 — or –CH2 CH2 O–, R is lower alkyl, allyl or cycloalkylalkyl and R’ is phenyl or phenyl monosubstituted by halo, alkyl, alkoxy or trifluoromethyl, Are prepared by oxidation of the corresponding dihydro intermediates.

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Benzofuran – Wikipedia,
Benzofuran | C8H460O – PubChem

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Quinolines as a novel structural class of potent and selective PDE4 inhibitors: Optimisation for oral administration

Crystallography-driven optimisation of a lead derived from similarity searching of the GSK compound collection resulted in the discovery of a series of quinoline derivatives that were highly potent and selective inhibitors of PDE4 with a good pharmacokinetic profile in the rat. Quinolines 43 and 48 have potential as oral medicines for the treatment of COPD.

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Benzofuran – Wikipedia,
Benzofuran | C8H481O – PubChem

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SULFONIMIDAMIDE COMPOUNDS AS INHIBITORS OF INTERLEUKIN-1 ACTIVITY

The present disclosure relates to novel sulfonimidamide compounds and related compounds and their use in treating a disorder responsive to modulation of cytokines such as IL-1beta and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process. (I)

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Benzofuran – Wikipedia,
Benzofuran | C8H469O – PubChem

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3′ SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY

The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I): wherein Q, R1, R4, m and Ar are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

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Benzofuran – Wikipedia,
Benzofuran | C8H463O – PubChem

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Indoline derivatives as 5-HT2C receptor agonists

A series of 1-(1-indolinyl)-2-propylamines was synthesised and evaluated as 5-HT2C receptor agonists for the treatment of obesity. The general methods of synthesis of the precursor indoles are described. The functional efficacy and radioligand binding data for all of the compounds at 5-HT 2 receptor subtypes are reported. A number of compounds were found to reduce food intake in rats after oral administration.

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Benzofuran – Wikipedia,
Benzofuran | C8H479O – PubChem